Yield10 Bioscience Researcher Dr. Frank Skraly to Present at the Plant Biology 2018 Conference
July 17 2018 - 8:00AM
Yield10 Bioscience, Inc. (Nasdaq:YTEN), a Company developing new
technologies to create step-change improvements in crop yield to
enhance global food security, announced that Frank Skraly, Ph.D.,
Senior Director of Metabolic Engineering, is presenting today at
the Plant Biology 2018 Conference, the annual meeting of the
American Society of Plant Biologists (ASPB). In Dr. Skraly’s
presentation, titled “Transporter manipulation in food crops for
increased yield,” he will discuss key aspects of Yield10’s
technology platform highlighting two case studies describing the
use of modeling carbon metabolism in crops to project crop yield
gene targets and outcomes. The Plant Biology 2018 Conference is
being held July 14-18 in Montreal, Canada.
Dr. Skraly will describe the use of advanced metabolic modeling
techniques as a means to model plant metabolism to identify and
evaluate potential yield targets. During his presentation, Dr.
Skraly will discuss two case studies. The first case models the
mechanism of action for the novel yield trait C3003. The second
case models the yield effect of a complex multi-gene pathway based
on a synthetic carbon fixation pathway. Research suggests that the
models can be used to project the range of yield improvement that
can be attained with a crop yield gene target and compares the
modeling results with experimental data from greenhouse or field
studies using Yield10’s Camelina platform.
CCP1 is a gene found in certain algal species and is induced
under low CO2 conditions. Yield10’s C3003 novel yield trait
gene is based on CCP1. Yield10 has previously reported that
expression of C3003 in Camelina has increased seed yield in a range
from 7% to 23% under field conditions. The modeling outlined in the
presentation explains why CCP1 may increase the efficiency of
carbon fixation and result in yield improvements of approximately
20%. The modeling also suggests that CCP1 may benefit seed
metabolism and identifies additional gene targets with the
potential to further improve the yield impact of C3003. Yield10 is
currently optimizing the deployment of C3003 and testing the trait
in field tests of Camelina, canola and soybean.
Yield10 researchers engineered a complex multi-gene pathway into
Camelina seeds to create an additional carbon fixation pathway.
Modeling projects that the engineered pathway should increase the
maximum theoretical seed yield in the engineered Camelina plants by
212%. Greenhouse results obtained for the pathway deployed in the
best performing Camelina plants included increases in seed yield of
173%, 216% and 228%. These results were published in Plant
Cell Reports in June 2018.
“Our modeling of new yield traits has been well correlated to
the experimental results obtained under greenhouse conditions or in
the field using our Camelina platform,” said Dr. Skraly. “The
modeling is providing us with insights for deploying new seed yield
traits and trait combinations that may boost seed yield by a
significant margin over seed available commercially
today.”
“Frank’s presentation highlights our metabolic engineering
approach and the unique perspective it can provide to develop new
ways to tackle the challenge of crop yield,” said Kristi Snell,
Ph.D., Chief Science Officer of Yield10 Bioscience. “This research
is extremely valuable in many respects, most importantly with
identifying new gene targets that may increase seed yield in
commercial row crops. This approach has produced a rich pipeline of
targets for Yield10 and we look forward to identifying additional
targets to boost crop yield.”
A copy of Dr. Skraly’s slide deck is available on the Yield10
Bioscience website.
About Yield10
Bioscience
Yield10 Bioscience, Inc. is focused on developing new
technologies to achieve step-change improvements in crop yield to
enhance global food security. Yield10 has an extensive track record
of innovation based around optimizing the flow of carbon in living
systems. Yield10 is leveraging its technology platforms and
unique knowledge base to design precise alterations to gene
activity and the flow of carbon in plants to produce higher yields
with lower inputs of land, water or fertilizer. Yield10 is
advancing several yield traits it has developed in crops such as
Camelina, canola, soybean and rice. Yield10 is headquartered in
Woburn, MA and has an Oilseeds Center of Excellence in Saskatoon,
Canada.
For more information about the company, please visit
www.yield10bio.com.
(YTEN-G)
Safe Harbor for Forward-Looking
Statements
This press release contains forward-looking statements which are
made pursuant to the safe harbor provisions of Section 27A of the
Securities Act of 1933, as amended, and Section 21E of the
Securities Exchange Act of 1934, as amended. The forward-looking
statements in this release do not constitute guarantees of future
performance. Investors are cautioned that statements in this press
release which are not strictly historical, including, without
limitation, the use of technology, including metabolic modeling
techniques, to successfully identify targets and develop systems to
increase crop yield, the amounts by which crop yield may be
increased, if at all, the predictability of modeling outcomes for
yield traits, the results of field tests of C3003 with Camelina,
canola and soybean and the predictive value of the Camelina
platform, constitute forward-looking statements. Such
forward-looking statements are subject to a number of risks and
uncertainties that could cause actual results to differ materially
from those anticipated, including the risks and uncertainties
detailed in Yield10 Bioscience's filings with the Securities and
Exchange Commission. Yield10 assumes no obligation to update any
forward-looking information contained in this press release or with
respect to the matters described
herein.
Contacts: Yield10
Bioscience:Lynne H. Brum, (617) 682-4693, LBrum@yield10bio.com
Investor Relations: Amato and Partners,
LLCadmin@amatoandpartners.com
Media Inquiries: Eric FischgrundFischtank Marketing and
PReric@fischtankpr.com
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