MOORESTOWN, N.J., April 6, 2021 /PRNewswire/ -- Tabula Rasa
HealthCare, Inc (TRHC) (NASDAQ: TRHC), a leading healthcare
technology company advancing the safe use of medications, today
announced publication of a research article, "Longitudinal
Association of a Medication Risk Score With Mortality Among
Ambulatory Patients Acquired Through Electronic Health Record Data"
in the Journal of Patient Safety (JPS).
The study, conducted by the DARTNet Institute and the Department
of Clinical Pharmacy, Skaggs School
of Pharmacy and Pharmaceutical Sciences, University of
Colorado in collaboration with TRHC's Precision
Pharmacotherapy Research and Development Institute, found the
risk of death increased with higher medication risk scores (MRS).
These results suggest that pharmaceutical interventions for
those with an elevated MRS could significantly improve medication
safety.
The appropriate use of medications is critical to avoid
harm. The study establishes TRHC's MedWise Risk Score™ as the
new, innovative standard for measuring risk that medication
regimens pose.
"This study provides evidence that the medication risk score can
be an effective predictor of mortality risk due to adverse drug
events (ADEs)," said TRHC Chair and CEO Calvin H. Knowlton, Ph.D. "TRHC's MedWise
Risk Score gives clients, physicians and pharmacists a crucial
clinical decision tool to identify and reduce medication risk,
helping to save lives and keep patients healthier."
The study used electronic health record (EHR) data from more
than 427,000 patients from multiple U.S. healthcare organizations
to calculate medication risk scores, using TRHC's proprietary
MedWise® technology. Higher MRS has been correlated to
increased ADEs, emergency department visits, and hospitalizations
in previous studies.
To better understand if the increase in the MedWise Risk Score
extends to increased mortality risk, researchers compared them with
incidents of electronic health record (EHR) recorded death. After
adjusting for common multi-morbidities and other conditions,
the study showed that patients with EHR-recorded deaths had
significantly higher MRS than others.
In addition, it was found that the risk varies by age group and
by MRS category where the highest risk was seen among patients in
the 30-49 year-age group that had an MRS of ≥20.
"This is a unique risk stratification model using drugs, not
disease, to identify patients at increased risk of adverse drug
effects, including death," said TRHC Precision Pharmacotherapy
Research and Development Institute Chief Operating Officer
Veronique Michaud. "The
results suggest that clinical pharmacy interventions among those
with elevated scores could improve medication safety for patients
taking multiple medications."
"The Tabula Rasa medication algorithms are highly correlated
with death and offer a remarkable opportunity to advance mediation
safety. This study showed that they can be effectively used with
electronic health record data. As they spread in clinical care
ongoing evaluation of the impact of these advanced algorithms on
clinical outcomes will be exciting next steps," said Wilson Pace, MD, FAAFP, Professor of Family
Medicine at the University of Colorado,
the Geen-Edelman Chair for Practiced-based Research, Director of
the American Academy of Family Physicians National Research Network
and a co-author of the Institute of Medicine Crossing the Quality
Chasm monograph on Preventing Medication Errors.
About Tabula Rasa HealthCare
Tabula Rasa HealthCare
(NASDAQ: TRHC) provides medication safety solutions that empower
healthcare professionals to optimize medication regimens and reduce
medication-related risk, specifically targeting adverse drug
events. TRHC's technology solutions, including DoseMeRx™ and
MedWise™, improve patient outcomes, reduce hospitalizations, and
lower healthcare costs. TRHC's extensive clinical tele-pharmacy
network improves care for patients nationwide. Its solutions are
trusted by health plans and pharmacies to help drive value-based
payment results. For more information, visit TRHC.com.
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SOURCE Tabula Rasa HealthCare, Inc.