Filed pursuant to Rule 424(b)(5)
Registration Statement No. 333-237542
Prospectus Supplement No. 2
(To Prospectus dated April 10, 2020)
American Depositary Shares Representing Ordinary
This prospectus supplement No. 2 supplements the prospectus
dated April 10, 2020 and the prospectus supplement dated
August 6, 2020 related to the offer and sale of our American
Depositary Shares, or ADSs, each representing 12 ordinary shares,
each with a nominal or par value of $0.0003 per share, pursuant to
an at-the-market offering
agreement, or the Sales Agreement, dated August 6, 2020, with H.C.
Wainwright & Co., LLC, as sales agent, in transactions
that are deemed to be “at-the-market” equity offerings
as defined in Rule 415 under the Securities Act of 1933, as
amended. As of the date of this prospectus supplement, we have
terminated the offer and sale of our ADSs in at-the-market offerings under
the sales agreement prospectus supplement.
As of the date of this prospectus supplement, we had not sold any
ADSs under the Sales Agreement.
Neither the Securities and Exchange Commission nor any state
securities commission has approved or disapproved of these
securities or passed upon the accuracy or adequacy of this
prospectus supplement or the accompanying prospectus. Any
representation to the contrary is a criminal offense.
The date of this prospectus supplement is
November 19, 2020