Passage Bio to Present Updated Imagine-1 Study Clinical and Biomarker Data at the American Society of Gene and Cell Therapy 25th Annual Meeting
May 02 2022 - 4:01PM
Passage Bio, Inc. (NASDAQ: PASG), a clinical-stage genetic
medicines company focused on developing transformative therapies
for central nervous system (CNS) disorders, today announced that
additional clinical and biomarker data from Cohort 1 in the
Imagine-1 study for GM1 gangliosidosis will be presented at the
upcoming American Society of Gene and Cell Therapy (ASGCT) 25th
Annual Meeting, which is being held in Washington D.C. and
virtually from May 16 to 19, 2022.
Late-breaker oral presentation details:
Title: Interim Safety, Biomarker, and Efficacy
Data From Imagine-1: A Phase 1/2 Open-label, Multicenter Study to
Assess the Safety, Tolerability, and Efficacy of a Single Dose, ICM
Administration of PBGM01 in Subjects with Type I (Early Onset) and
Type IIa (Late Onset) Infantile GM1
GangliosidosisDate/Time: Wednesday, May 18, 2022
from 8:30 a.m. to 8:45 a.m. ETRoom: Ballroom
CPresenter: Weinstein DAAbstract
Number: 2257
Additionally, scientists at the Gene Therapy Program (GTP) at
the University of Pennsylvania will present several abstract
presentations containing additional preclinical data across
multiple earlier-stage Passage Bio programs. The data to be
presented in the following poster supported Passage Bio’s
Investigational New Drug submission for MLD to the U.S. Food and
Drug Administration.
Title: Long-term evaluation of the efficacy of
intracerebroventricularly injected AAVhu68 encoding human codon
optimized ARSA (hARSA) transgene in a mouse model of Metachromatic
leukodystrophy (MLD)Date/Time: Wednesday, May 18,
2022 from 5:30 p.m. to 6:30 p.m. ETPresenter:
Choudhury GRAbstract Number: 1024
About Passage BioAt Passage Bio (Nasdaq: PASG),
we are on a mission to provide life-transforming genetic medicines
for patients with CNS diseases that replace their suffering with
boundless possibility, all while building lasting relationships
with the communities we serve. Based in Philadelphia, PA, our
company has established a strategic collaboration and licensing
agreement with the renowned University of Pennsylvania’s Gene
Therapy Program to conduct our discovery and IND-enabling
preclinical work. This provides our team with enhanced access to a
broad portfolio of gene therapy candidates and future gene therapy
innovations that we then pair with our deep clinical, regulatory,
manufacturing and commercial expertise to rapidly advance our
robust pipeline of optimized gene therapies into clinical testing.
As we work with speed and tenacity, we are always mindful of
patients who may be able to benefit from our therapies. More
information is available at www.passagebio.com.
For further information, please contact:
Investors:Stuart HendersonPassage
Bio267.866.0114shenderson@passagebio.com
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