InflaRx (Nasdaq: IFRX), a clinical-stage biopharmaceutical company
developing anti-inflammatory therapeutics by targeting the
complement system, announced today financial results for the year
ending December 31, 2019.
“The Company underwent significant changes in
2019 and has selected a compelling set of high unmet medical need
indications for its lead drug candidate IFX-1,” said Prof. Niels C.
Riedemann, Chief Executive Officer and Founder of InflaRx. “The
Company has also provided new evidence supporting the activity of
IFX-1 in neutrophil-driven skin diseases, which continue to be a
clear focus. With our current cash position and future value
inflection points, we believe InflaRx is well positioned to weather
the current global environment.”
Prof. Riedemann continued, “With the recently
initiated trial in severe progressed COVID-19 pneumonia, our
Company is making a strong contribution to help identify potential
treatment options for patients during this global pandemic, which
is based on several years of in-house research on the role of
C5a-driven lung injury and viral pneumonia.”
Corporate and
R&D highlights – 2019 through
early 2020
Corporate
- Entered into a clinical collaboration agreement with Merck
& Co, Inc., Kenilworth, NJ, USA (known as MSD outside the US
and Canada) to evaluate the combination of IFX-1 and Merck’s
anti-PD-1 therapy, KEYTRUDA® (pembrolizumab) in patients with an
undisclosed tumor type. Under the terms of the agreement, InflaRx
will conduct a Phase IIa clinical study with two IFX-1 arms,
including one with KEYTRUDA®. KEYTRUDA® is a registered
trademark of Merck Sharp & Dohme Corp., Whitehouse Station, New
Jersey, U.S.A, a subsidiary of Merck & Co., Inc., Kenilworth,
NJ, USA.
- Hired senior executives for key positions – Jordan Zwick
(formerly of Bausch Health) as Global Head of Business Development
and Corporate Strategy and Dr. Korinna Pilz as Global Head of
Clinical Research and Development (>20 years of clinical
development experience in different pharmaceutical companies,
including Roche, Bayer, Boehringer Ingelheim and others).
- Expanding research and development activities supported by
growth in number of employees to 45 as of December 31, 2019 (up
from 38 in 2018).
Lead product candidate, IFX-1, first-in-class
anti-human complement factor C5a antibody
Hidradenitis Suppurativa (HS)
- On June 5, 2019, the Company announced top-line results of the
international SHINE Phase IIb study, investigating the safety and
efficacy of IFX-1 in patients suffering from moderate to severe
Hidradenitis Suppurativa (HS). The randomized, double-blind,
placebo-controlled, multicenter study enrolled a total of 179
patients in four active dose arms and a placebo arm at over 40
sites in 9 countries in North America and Europe. The primary
endpoint of the trial was not met, which was a dose response
signal, assessed by HiSCR1 at week 16. The primary statistical
analysis by multiple-comparison procedure modelling (MCP-mod)
showed no significant dose response, but the IFX-1 treatment was
well tolerated.
- On July 18, 2019 the Company published a post-hoc analysis
demonstrating additional signals of efficacy for the IFX-1 high
dose group compared to the placebo group within the initial phase
of the SHINE study, including reductions in all combined
inflammatory lesions, on draining fistula and on the International
Hidradenitis Suppurativa Severity Score 4 (IHS4), which scores all
inflammatory lesions. IHS4 was developed by an international
expert group to score severity and track treatment response,
although the score has not been utilized as a primary endpoint in
late stage clinical studies in HS. The IHS4 weighs the most
fluctuating lesions: inflammatory nodules (1 point), less than
abscesses (2 points) or draining fistulas (4 points).
- On November 6, 2019, the Company reported positive results from
the open label extension (OLE) part of the international SHINE
Phase IIb study. The data were from a snapshot analysis at the end
of the overall 9-month study treatment period (week 40). A total of
156 patients entered the 6-month OLE period upon completion of the
16-week initial phase of the SHINE study. Overall, patients
completing the OLE period showed a sustained improvement in
inflammatory lesion count at week 40 compared to baseline counts of
the OLE treatment group on day 1 of the SHINE study.
- In Q1 2020, the Company requested an FDA End of Phase II
meeting to discuss the path forward for a pivotal program with
IFX-1 in HS. The meeting has been scheduled for mid-year.
ANCA-associated vasculitis (AAV)
- Since October 2018, 19 patients have been recruited in the
randomized, triple-blind, placebo-controlled US Phase II IXPLORE
study with IFX-1 in patients with AAV. The main objective of the
study is to evaluate the efficacy and safety of two dose regimens
of IFX-1 in patients with moderate to severe AAV when dosed on top
of standard of care, which includes treatment with high dose
glucocorticoids. The trial originally planned to enroll
approximately 36 patients at centers in the US. Based on a blinded
interim analysis and assessment of the potential impact of the
COVID-19 pandemic, the Company has decided to stop the study and
read out the existing results earlier than initially planned as
part of a strategy to align and streamline the US and EU AAV
development program.
- In May 2019, the Company initiated a randomized, double-blind,
placebo-controlled European Phase II IXCHANGE study with IFX-1 in
patients with AAV. The main objective of the study is to evaluate
the efficacy and safety of IFX-1 in patients with moderate to
severe AAV. The primary endpoint of the study is a 50% reduction in
Birmingham Vasculitis Activity Score (BVAS) at week 16. The study
was originally planned to enroll approximately 80 patients at about
60 sites in up to 12 European countries and Russia. The study is
being conducted in two parts. In Part 1, patients are being
randomized to receive either IFX-1 plus a reduced dose of
glucocorticoids or placebo plus a standard dose of glucocorticoids.
Patients in both arms receive the standard of care dosing of
immunosuppressive therapy (rituximab or cyclophosphamide). In Part
2 of the study, patients will be randomized to receive either IFX-1
plus placebo glucocorticoids or placebo plus a standard dose of
glucocorticoids (both on top of standard of care immunosuppressive
therapy with rituximab or cyclophosphamide). The first part of the
study has been fully enrolled. After analyzing the impact of
COVID-19 on the study, a blinded interim analysis of Part 1 has
been completed. Based on the analysis, the Company intends to
continue with Part 2 of the study but decrease the number of
enrolled patients.
Pyoderma Gangraenosum (PG)
- In February 2019, the Company received approval from Health
Canada to initiate an open label Phase IIa exploratory study with a
plan to enroll 18 patients with moderate to severe PG. The
objectives of this study are to evaluate the safety and efficacy of
IFX-1 in this patient population.
- In February 2020, the Company announced positive initial data
from the first 5 patients dosed in this Phase IIa open label study.
Of these 5 initial patients dosed with IFX-1, 2 patients achieved
complete closure of the target ulcer and complete healing of all
other PG ulcers. The drug was well tolerated and no drug-related
severe adverse events (SAEs) have been recorded to date in the
study. The study continues to enroll patients with the addition of
two higher dose cohorts.
COVID-19 Pneumonia
- In March 2020, the Company initiated a Phase II clinical
development program with IFX-1 in COVID-19 patients with severely
progressed pneumonia and enrolled the first patient at the
Amsterdam University Medical Centers in the Netherlands. Additional
centers have since been opened in the Netherlands. In the study,
patients are being randomized to two treatment arms - either Arm A,
best supportive care and IFX-1, or Arm B, best supportive care
alone. The primary endpoint is the relative percentage change from
baseline to day 5 in the Oxygenation Index (PaO2 / FiO2). After all
patients have been treated in the first part of the trial, an
interim analysis will be performed to assess the clinical benefit
of the treatment using the assessed clinical parameters in order to
potentially adapt the confirmatory second part of the study.
Part 1 is fully enrolled with 30 patients as of April 24,
2020.
2019 financial
highlights
Research and development
expenses increased by €19.6 million to €44.6 million in
2019, from €25.0 million in 2018. This increase was primarily
attributable to a €20.9 million increase in clinical research and
manufacturing organizations (CRO and CMO) costs related to IFX-1 in
connection with the Phase IIb clinical trial in patients with HS,
the Phase II clinical program in patients with AAV, the Phase II
clinical program in patients with PG, the preparation of a Phase II
clinical program in oncology as well as with the ongoing
manufacturing activities for clinical trial-related material. In
addition, there was a €1.8 million decrease in employee-related
costs mainly due to a €2.6 million anticipated decrease in expenses
related to non-cash share-based compensation.
General and administrative
expenses decreased by €0.3 million to €12.5 million in
2019, from €12.8 million in 2018. This decrease was primarily
attributable to a €1.6 million decrease in employee-related costs
associated with a €2.6 million anticipated decrease in non-cash
share-based compensation, partially offset by €1.0 million higher
personnel expense due to new hires. Legal, consulting and audit
fees and other expenses increased by €0.2 million to €2.2 million
in 2019, from €2.0 million in 2018, the increase being mainly
attributable to higher consulting costs. The increase in other
expenses of €1.1 million is primarily related to higher D&O
insurance costs, IT and office expenses.
Net financial result decreased
by €4.2 million to €3.5 million in 2019, from €7.7 million in 2018.
This change was mainly attributable to lower foreign exchange
gains, which decreased by €4.8 million, partially offset by
interest on marketable securities, which increased by €0.6
million.
Net loss for the year 2019 was
€53.3 million or €2.05 per common share, compared to €29.8 million
or €1.19 per common share for the year 2018. On December 31, 2019,
the Company’s total funds available were €115.8
million, mostly composed of cash and cash equivalents (€33.1
million) and marketable securities (€81.9 million).
Net cash used in operating
activities increased to €43.2 million in 2019, from €21.5
million in 2018, mainly due to the increase in research and
development expenditures and higher personnel costs, excluding
stock-based compensation.Additional information regarding these
results is included in the notes to the consolidated financial
statements as of December 31, 2019 and “ITEM 18. Financial
statements,” which will be included in InflaRx’s Annual Report on
Form 20-F as filed with the U.S. Securities and Exchange Commission
on April 29, 2020.
InflaRx N.V. and
subsidiaryConsolidated Statements
of Comprehensive Loss for the Years Ended December 31, 2019,
2018 and 2017
in € |
2019 |
|
2018 |
|
2017 |
|
|
|
|
Operating
Expenses |
|
|
|
Research and development expenses |
(44,582,136 |
) |
|
(25,028,554 |
) |
|
(14,414,628 |
) |
General and administrative
expenses |
(12,501,048 |
) |
|
(12,786,869 |
) |
|
(5,138,498 |
) |
Total Operating
Expenses |
(57,083,184 |
) |
|
(37,815,422 |
) |
|
(19,553,126 |
) |
Other income |
400,253 |
|
|
303,860 |
|
|
115,525 |
|
Other expenses |
(85,242 |
) |
|
(4,802 |
) |
|
(7,644 |
) |
Operating
Result |
(56,768,173 |
) |
|
(37,516,364 |
) |
|
(19,445,245 |
) |
Finance income |
6,220,320 |
|
|
10,432,695 |
|
|
130,032 |
|
Finance expenses |
(2,706,964 |
) |
|
(2,730,964 |
) |
|
(4,922,535 |
) |
Net Financial
Result |
3,513,355 |
|
|
7,701,731 |
|
|
(4,792,503 |
) |
Loss for the
Period |
(53,254,817 |
) |
|
(29,814,634 |
) |
|
(24,237,748 |
) |
|
|
|
|
Share
Information |
|
|
|
Weighted average number of
shares outstanding |
26,004,519 |
|
|
25,095,027 |
|
|
9,410,524 |
|
Loss per share in euro
(basic/diluted) |
(2.05 |
) |
|
(1.19 |
) |
|
(2.58 |
) |
|
|
|
|
|
|
|
|
|
Loss for the
Period |
(53,254,817 |
) |
|
(29,814,634 |
) |
|
(24,237,748 |
) |
Other comprehensive income
that may be reclassified to profit or loss in subsequent
periods: |
|
|
|
Exchange differences on
translation of operations in foreign currency |
2,177,033 |
|
|
50,196 |
|
|
— |
|
Total Comprehensive
Loss |
(51,077,785 |
) |
|
(29,764,438 |
) |
|
(24,237,748 |
) |
|
InflaRx N.V. and
subsidiaryConsolidated Statements
of Financial Position as of December 31, 2019 and
2018
in € |
2019 |
|
2018 |
|
|
|
ASSETS |
|
|
Non-current
assets |
|
|
Property, plant and equipment |
1,413,297 |
|
|
624,668 |
|
Intangible assets |
452,400 |
|
|
222,866 |
|
Non-current other non-financial
assets |
452,217 |
|
|
— |
|
Non-current financial assets |
272,614 |
|
|
207,444 |
|
Total non-current
assets |
2,590,528 |
|
|
1,054,979 |
|
Current
assets |
|
|
Current other non-financial
assets |
3,500,884 |
|
|
1,588,702 |
|
Current financial assets |
82,353,867 |
|
|
101,184,240 |
|
Cash and cash equivalents |
33,131,280 |
|
|
55,386,240 |
|
Total current
assets |
118,986,031 |
|
|
158,159,183 |
|
TOTAL
ASSETS |
121,576,558 |
|
|
159,214,161 |
|
|
|
|
EQUITY AND
LIABILITIES |
|
|
Equity |
|
|
Issued capital |
3,132,631 |
|
|
3,115,725 |
|
Share premium |
211,006,606 |
|
|
211,021,835 |
|
Other capital reserves |
25,142,213 |
|
|
18,310,003 |
|
Accumulated deficit |
(134,362,006 |
) |
|
(81,107,188 |
) |
Other components of
equity |
2,227,228 |
|
|
50,196 |
|
Total
equity |
107,146,673 |
|
|
151,390,571 |
|
Non-current
liabilities |
|
|
Lease liabilities |
330,745 |
|
|
— |
|
Provisions and Government
grants |
39,013 |
|
|
67,945 |
|
Total non-current
liabilities |
369,758 |
|
|
67,945 |
|
Current
liabilities |
|
|
Lease liabilities |
515,203 |
|
|
— |
|
Employee Benefits |
975,629 |
|
|
789,800 |
|
Social securities, other tax and
non-financial liabilities |
105,634 |
|
|
308,533 |
|
Trade and other payables |
12,413,662 |
|
|
6,657,312 |
|
Provisions |
50,000 |
|
|
— |
|
Total current
liabilities |
14,060,128 |
|
|
7,755,645 |
|
Total
Liabilities |
14,429,886 |
|
|
7,823,590 |
|
TOTAL EQUITY AND
LIABILITIES |
121,576,558 |
|
|
159,214,161 |
|
|
InflaRx N.V. and
subsidiaryConsolidated Statements
of Changes in Shareholders’ Equity for the Years Ended December 31,
2019, 2018 and 2017
in € |
Issued capital |
|
Share premium |
|
Other capital reserves |
|
Accumulated deficit |
|
Other components of equity |
|
Total equity |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Balance at January 1, 2017 |
31,428 |
|
— |
|
|
1,325,006 |
|
(27,054,806 |
) |
|
8,839 |
|
|
(25,689,533 |
) |
Loss for the Period |
— |
|
— |
|
|
— |
|
(24,237,748 |
) |
|
— |
|
|
(24,237,748 |
) |
Exchange differences on
translation of operations in foreign currency |
— |
|
— |
|
|
— |
|
— |
|
|
— |
|
|
— |
|
Total Comprehensive
Loss |
— |
|
— |
|
|
— |
|
(24,237,748 |
) |
|
— |
|
|
(24,237,748 |
) |
Transactions with owners
of the Company |
|
|
|
|
|
|
|
Contributions |
|
|
|
|
|
|
|
Issue of common shares |
848,175 |
|
90,055,312 |
|
|
— |
|
— |
|
|
— |
|
|
90,903,488 |
|
Transaction costs |
— |
|
(9,114,770 |
) |
|
— |
|
— |
|
|
— |
|
|
(9,114,770 |
) |
Equity-settled share-based
payment |
— |
|
— |
|
|
4,550,105 |
|
— |
|
|
— |
|
|
4,550,105 |
|
Total
Contributions |
848,175 |
|
80,940,542 |
|
|
4,550,105 |
|
— |
|
|
— |
|
|
86,338,823 |
|
Changes in ownership
interests |
|
|
|
|
|
|
|
Reorganization |
1,977,849 |
|
80,698,025 |
|
|
350,242 |
|
— |
|
|
— |
|
|
83,026,115 |
|
Liquidation of a Subsidiary |
— |
|
— |
|
|
— |
|
— |
|
|
(8,839 |
) |
|
(8,839 |
) |
Total changes in
ownership interests |
1,977,849 |
|
80,698,025 |
|
|
350,242 |
|
— |
|
|
(8,839 |
) |
|
83,017,276 |
|
Total transactions with
owners of the Company |
2,826,024 |
|
161,638,566 |
|
|
4,900,347 |
|
— |
|
|
(8,839 |
) |
|
169,356,099 |
|
Balance at December
31, 2017 |
2,857,452 |
|
161,638,566 |
|
|
6,225,353 |
|
(51,292,555 |
) |
|
— |
|
|
119,428,816 |
|
Loss for the period |
— |
|
— |
|
|
— |
|
(29,814,634 |
) |
|
— |
|
|
(29,814,634 |
) |
Exchange differences on
translation of operations in foreign currency |
— |
|
— |
|
|
— |
|
— |
|
|
50,196 |
|
|
50,196 |
|
Total comprehensive
loss |
— |
|
— |
|
|
— |
|
(29,814,634 |
) |
|
50,196 |
|
|
(29,764,438 |
) |
Transactions with
owners of the Company |
|
|
|
|
|
|
|
Contributions |
|
|
|
|
|
|
|
Issue of common shares |
222,000 |
|
52,768,733 |
|
|
— |
|
— |
|
|
— |
|
|
52,990,733 |
|
Transaction costs |
— |
|
(3,801,265 |
) |
|
— |
|
— |
|
|
— |
|
|
(3,801,265 |
) |
Equity-settled share-based
payment |
— |
|
— |
|
|
12,084,651 |
|
— |
|
|
— |
|
|
12,084,651 |
|
Share options exercised |
36,273 |
|
415,801 |
|
|
— |
|
— |
|
|
— |
|
|
452,074 |
|
Total
Contributions |
258,273 |
|
49,383,269 |
|
|
12,084,651 |
|
— |
|
|
— |
|
|
61,726,193 |
|
Total transactions
with owners of the Company |
258,273 |
|
49,383,269 |
|
|
12,084,651 |
|
— |
|
|
— |
|
|
61,726,193 |
|
Balance at December
31, 2018 |
3,115,725 |
|
211,021,835 |
|
|
18,310,003 |
|
(81,107,188 |
) |
|
50,196 |
|
|
151,390,571 |
|
Loss for the period |
— |
|
— |
|
|
— |
|
(53,254,817 |
) |
|
— |
|
|
(53,254,817 |
) |
Exchange differences on
translation of operations in foreign currency |
— |
|
— |
|
|
— |
|
— |
|
|
2,177,033 |
|
|
2,177,033 |
|
Total comprehensive
loss |
— |
|
— |
|
|
— |
|
(53,254,817 |
) |
|
2,177,033 |
|
|
(51,077,784 |
) |
Transactions with
owners of the Company |
|
|
|
|
|
|
|
Contributions |
|
|
|
|
|
|
|
Equity-settled share-based
payment |
— |
|
— |
|
|
6,832,210 |
|
— |
|
|
— |
|
|
6,832,210 |
|
Share options exercised |
16,905 |
|
(15,229 |
) |
|
— |
|
— |
|
|
— |
|
|
1,676 |
|
Total
Contributions |
16,905 |
|
(15,229 |
) |
|
6,832,210 |
|
— |
|
|
— |
|
|
6,833,886 |
|
Total transactions
with owners of the Company |
16,905 |
|
(15,229 |
) |
|
6,832,210 |
|
— |
|
|
— |
|
|
6,833,886 |
|
Balance at December
31, 2019 |
3,132,631 |
|
211,006,606 |
|
|
25,142,213 |
|
(134,362,006 |
) |
|
2,227,228 |
|
|
107,146,673 |
|
InflaRx N.V. and
subsidiaryConsolidated Statements
of Cash Flows for the Years ended December 31, 2019, 2018 and
2017
in € |
2019 |
|
2018 |
|
2017 |
|
|
|
|
Operating
activities |
|
|
|
Loss for the period |
(53,254,817 |
) |
|
(29,814,634 |
) |
|
(24,237,748 |
) |
Adjustments for: |
|
|
|
Depreciation & Amortization |
663,166 |
|
|
173,630 |
|
|
70,910 |
|
Net Financial Result |
(3,513,355 |
) |
|
(7,701,731 |
) |
|
4,792,503 |
|
Share based payment expense |
6,832,210 |
|
|
12,084,651 |
|
|
4,550,105 |
|
Other non-cash adjustments |
(307,849 |
) |
|
196,699 |
|
|
24,076 |
|
Changes in: |
|
|
|
Other non-financial assets |
(2,364,399 |
) |
|
(893,602 |
) |
|
(522,818 |
) |
Current financial assets |
— |
|
|
(316,112 |
) |
|
89,599 |
|
Employee benefits |
235,500 |
|
|
494,837 |
|
|
132,305 |
|
Social securities, other tax and non-financial liabilities |
(209,948 |
) |
|
304,627 |
|
|
(30,024 |
) |
Trade and other payables |
5,734,795 |
|
|
2,243,137 |
|
|
2,912,740 |
|
Interest received |
3,001,109 |
|
|
1,679,250 |
|
|
66,391 |
|
Interest paid |
(20,903 |
) |
|
— |
|
|
— |
|
Net cash flows from
operating activities |
(43,204,492 |
) |
|
(21,549,248 |
) |
|
(12,151,962 |
) |
Investing
activities |
|
|
|
Cash outflow from the purchase of
intangible assets, laboratory and office equipment |
(594,889 |
) |
|
(806,531 |
) |
|
(148,542 |
) |
Cash outflow for the investment
in non-current other financial assets |
(75,543 |
) |
|
(209,705 |
) |
|
(18,481 |
) |
Proceeds from the disposal of
non-current other financial assets |
— |
|
|
21,811 |
|
|
— |
|
Proceeds from the disposal of
current financial assets or repayment of maturing securities |
103,559,395 |
|
|
7,990,204 |
|
|
— |
|
Purchase of current &
non-current financial assets |
(82,547,409 |
) |
|
(106,445,120 |
) |
|
— |
|
Net cash flows from
investing activities |
20,341,554 |
|
|
(99,451,341 |
) |
|
(167,023 |
) |
Financing
activities |
|
|
|
Proceeds from issuance of share
capital |
— |
|
|
52,990,733 |
|
|
90,903,488 |
|
Transaction cost from issuance of
share capital |
— |
|
|
(3,801,265 |
) |
|
(9,114,770 |
) |
Proceeds from exercise of share
options |
1,676 |
|
|
452,075 |
|
|
— |
|
Proceeds from issuance of
preferred shares |
— |
|
|
— |
|
|
27,012,050 |
|
Repayment of leasing debt |
(296,020 |
) |
|
— |
|
|
— |
|
Net cash flows from
financing activities |
(294,344 |
) |
|
49,641,542 |
|
|
108,800,767 |
|
Effect of exchange rate
changes |
902,321 |
|
|
3,461,399 |
|
|
(2,316,631 |
) |
Net change in cash and
cash equivalents |
(22,254,960 |
) |
|
(71,357,047 |
) |
|
94,165,152 |
|
Cash and cash equivalents at
beginning of period |
55,386,240 |
|
|
123,281,888 |
|
|
29,116,737 |
|
Cash and cash equivalents
at end of period |
33,131,280 |
|
|
55,386,240 |
|
|
123,281,888 |
|
|
|
|
|
About IFX-1:
IFX-1 is a first-in-class monoclonal anti-human
complement factor C5a antibody, which highly and effectively blocks
the biological activity of C5a and demonstrates high selectivity
towards its target in human blood. Thus, IFX-1 leaves the formation
of the membrane attack complex (C5b-9) intact as an important
defense mechanism, which is not the case for molecules blocking the
cleavage of C5. IFX-1 has been demonstrated to control the
inflammatory response driven tissue and organ damage by
specifically blocking C5a as a key “amplifier” of this response in
pre-clinical studies. IFX-1 is believed to be the first monoclonal
anti-C5a antibody introduced into clinical development.
Approximately 300 people have been treated with IFX-1 in clinical
trials, and the antibody has been shown to be well tolerated. IFX-1
is currently being developed for various indications, including
Hidradenitis Suppurativa, ANCA-associated vasculitis, Pyoderma
Gangraenosum and COVID-19 pneumonia.
About InflaRx N.V.:
InflaRx (Nasdaq: IFRX) is a clinical-stage
biopharmaceutical company focused on applying its proprietary
anti-C5a technology to discover and develop first-in-class, potent
and specific inhibitors of C5a. Complement C5a is a powerful
inflammatory mediator involved in the progression of a wide variety
of autoimmune and other inflammatory diseases. InflaRx was founded
in 2007, and the group has offices and subsidiaries in Jena and
Munich, Germany, as well as Ann Arbor, MI, USA. For further
information please visit www.inflarx.com.
Contacts:
InflaRx N.V.Jordan Zwick –
Global Head of Business Development & Corporate StrategyEmail:
jordan.zwick[at]inflarx.deTel: +1 917-338-6523
MC Services AGKatja Arnold,
Laurie Doyle, Andreas Jungfer Email: inflarx[at]mc-services.eu
Europe: +49 89-210 2280US: +1 339-832-0752
FORWARD-LOOKING STATEMENTS
This press release contains forward-looking
statements. All statements other than statements of historical fact
are forward-looking statements, which are often indicated by terms
such as “may,” “will,” “should,” “expect,” “plan,” “anticipate,”
“could,” “intend,” “target,” “project,” “estimate,” “believe,”
“predict,” “potential” or “continue” and similar expressions.
Forward-looking statements appear in a number of places throughout
this release and may include statements regarding our intentions,
beliefs, projections, outlook, analyses and current expectations
concerning, among other things, our ongoing and planned preclinical
development and clinical trials, the impact of the COVID-19
pandemic on the Company, the timing and our ability to commence and
conduct clinical trials, potential results from current or
potential future collaborations, our ability to make regulatory
filings, obtain positive guidance from regulators, and obtain and
maintain regulatory approvals for our product candidates, our
intellectual property position, our ability to develop commercial
functions, expectations regarding clinical trial data, our results
of operations, cash needs, financial condition, liquidity,
prospects, future transactions, growth and strategies, the industry
in which we operate, the trends that may affect the industry or us
and the risks, uncertainties and other factors described under the
heading “Risk Factors” in InflaRx’s periodic filings with the U.S.
Securities and Exchange Commission. These statements speak only as
of the date of this press release and involve known and unknown
risks, uncertainties and other important factors that may cause our
actual results, performance or achievements to be materially
different from any future results, performance or achievements
expressed or implied by the forward-looking statements. Given these
risks, uncertainties and other factors, you should not place undue
reliance on these forward-looking statements, and we assume no
obligation to update these forward-looking statements, even if new
information becomes available in the future, except as required by
law.
1 HiSCR response defined as: At least a 50%
reduction in total AN count (abscesses & inflammatory nodules)
with no increase in the number of abscesses from baseline and no
increase in the number of draining fistulas from baseline
InflaRx NV (NASDAQ:IFRX)
Historical Stock Chart
From Mar 2024 to Apr 2024
InflaRx NV (NASDAQ:IFRX)
Historical Stock Chart
From Apr 2023 to Apr 2024