Cara Therapeutics, Inc. (Nasdaq: CARA), an early commercial-stage biopharmaceutical company leading a new treatment paradigm to improve the lives of patients suffering from pruritus, today announced biomarker data from the KARE Phase 2 clinical trial evaluating Oral KORSUVA™ (difelikefalin) for the treatment of moderate-to-severe pruritus in atopic dermatitis patients will be presented in a late-breaking oral presentation at the 2022 American Academy of Dermatology (AAD) Annual Meeting, to be held March 25-29, 2022, in Boston, MA.

Details for the late-breaking oral presentation are as follows:

Title: Oral Difelikefalin Improves Itch and Inflammatory Biomarkers in Atopic Dermatitis Subjects With Moderate-to-Severe PruritusSession: S026 Late-Breaking Research: Clinical Trials Date and Time: Saturday, March 26, 2022, 9:40 a.m. ETLocation: Room 210APresenter: Paola Facheris, MD, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy

Virtual R&D Event

As previously announced, Cara Therapeutics will be hosting a virtual R&D event at 1:00 p.m. ET on March 11, 2022, which will focus on the initiation of Oral KORSUVA (difelikefalin) Phase 3 programs for the treatment of pruritus in patients with non-dialysis dependent advanced chronic kidney disease and atopic dermatitis, respectively. An interactive Q&A session will follow the presentation. Presenters will include:

  • Christopher Posner, President & Chief Executive Officer and Director of Cara Therapeutics
  • Joana Goncalves, MD, Chief Medical Officer of Cara Therapeutics
  • Brian Kim, MD, MTR, Icahn School of Medicine at Mount Sinai, NY
  • Jonathan Silverberg, MD, PhD, MPH, George Washington University School of Medicine and Health Sciences

A live audio webcast of the presentation and accompanying slides will be accessible under “Events & Presentations” in the News & Investors section of the Company’s website at www.CaraTherapeutics.com. A replay of the webcast will be archived on the Company’s website following the presentation.  

About Cara Therapeutics

Cara Therapeutics is an early commercial-stage biopharmaceutical company leading a new treatment paradigm to improve the lives of patients suffering from pruritus. The Company’s novel KORSUVA™ (difelikefalin) injection is the first and only FDA-approved treatment for moderate-to-severe pruritus associated with chronic kidney disease in adults undergoing hemodialysis. The Company is developing an oral formulation of difelikefalin and plans to initiate Phase 3 programs in the first quarter of 2022 for the treatment of pruritus in patients with non-dialysis-dependent advanced chronic kidney disease and atopic dermatitis. Phase 2 trials of Oral KORSUVA (difelikefalin) are ongoing in primary biliary cholangitis and notalgia paresthetica patients with moderate-to-severe pruritus. For more information, visit www.CaraTherapeutics.com and follow the company on Twitter, LinkedIn and Instagram.

MEDIA CONTACT:Annie Spinetta6 Degrees973-768-2170aspinetta@6degreespr.com

INVESTOR CONTACT:Iris Francesconi, Ph.D.Cara Therapeutics203-406-3700investor@caratherapeutics.com

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