FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                       
1. Name and Address of Reporting Person * LAU JOHNSON YIU NAM 2. Issuer Name and Ticker or Trading Symbol Athenex, Inc. [ ATNX ] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable)__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
CEO and Chairman of the Board
(Last)          (First)          (Middle)
C/O ATHENEX, INC., 1001 MAIN STREET, SUITE 600		 3. Date of Earliest Transaction (MM/DD/YYYY)
12/16/2022
(Street)
BUFFALO, NY 14203
(City)        (State)        (Zip)
 4. If Amendment, Date Original Filed (MM/DD/YYYY)
 
 6. Individual or Joint/Group Filing (Check Applicable Line) _X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock  12/16/2022    A    96284  A $0.1184 (1) 4029837  D   
Common Stock                 678880  I (2)(3) By Avalon Biomedical (Management) Limited (2)(3)
Common Stock                 164925  I (3) By Spouse (3)
Common Stock                 107181 (4) I (2)(3)(4) By Avalon Polytom (HK) Limited (2)(3)(4)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy)  $4.55                  1/2/2013  1/2/2023  Common Stock  1200000    1200000  D   
Stock Option (Right to Buy)  $7.50                  5/22/2018  5/22/2025  Common Stock  1400000    1400000  D   
Stock Option (Right to Buy)  $11.00                  6/13/2018  6/13/2027  Common Stock  1    1  D   
Stock Option (Right to Buy)  $9.00                  7/17/2019  7/17/2025  Common Stock  54904    54904  I (2)(3) By Avalon Biomedical (Management) Limited (2)(3)
Stock Option (Right to Buy)  $17.30                  3/27/2022  3/27/2028  Common Stock  250000    250000  D   
Stock Option (Right to Buy)  $13.17                   (5) 2/28/2029  Common Stock  250000    250000  D   
Stock Option (Right to Buy)  $7.32                  12/31/2020  3/24/2030  Common Stock  55045    55045  D   
Stock Option (Right to Buy)  $12.45                   (6) 6/5/2030  Common Stock  300000    300000  D   
Stock Option (Right to Buy)  $3.80                   (7) 8/3/2031  Common Stock  150000    150000  D   
Restricted Stock Units   (8)                  (9)  (9) Common Stock  112500    112500  D   
Stock Option (Right to Buy)  $0.6655                   (10) 7/20/2032  Common Stock  250000    250000  D   

Explanation of Responses:
(1)  Shares purchased from the Issuer under a Salary Deduction and Stock Purchase Agreement at the Nasdaq Official Closing Price on the date of purchase.
(2)  Avalon Biomedical (Management) Limited ("Avalon Biomedical") is an indirect wholly-owned subsidiary of Avalon Global Holdings Limited ("Avalon Global"). Dr. Johnson Lau ("Dr. Lau") owns all of the outstanding interests in Creative Decade Global Limited, which owns 34.63% of the outstanding interests in Avalon Global, and Dr. Lau serves on the board of directors of Avalon Global and has shared voting and dispositive power with respect to the shares held by Avalon Biomedical.
(3)  Dr. Lau disclaims beneficial ownership of the reported securities except to the extent, if any, of its or his pecuniary interest therein, and this report shall not be deemed an admission that Dr. Lau is the beneficial owner of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose.
(4)  These shares were acquired pursuant to the terms of a License Agreement dated as of June 29, 2018 by and between Athenex Therapeutics Limited, a wholly-owned subsidiary of Athenex, Inc. ("Athenex") and Avalon Polytom (HK) Limited, a majority-owned affiliate of Avalon Global. The number of shares was determined by dividing $2.0 million by the closing price of Athenex common stock on June 29, 2018.
(5)  This option vests in four equal annual installments beginning on February 28, 2020.
(6)  This option vests in four equal annual installments beginning on June 5, 2021.
(7)  This option vests in four equal annual installments beginning on August 3, 2022.
(8)  Each restricted stock unit represents a contingent right to receive one share of stock.
(9)  The restricted stock units vest in four equal annual installments beginning on August 3, 2022.
(10)  This option vests in four equal annual installments beginning on July 20, 2023.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
LAU JOHNSON YIU NAM
C/O ATHENEX, INC.
1001 MAIN STREET, SUITE 600
BUFFALO, NY 14203		 X
CEO and Chairman of the Board

Signatures
/s/Steven Adams, Attorney-in-Fact 12/20/2022
**Signature of Reporting Person Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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