International stocks trading in New York closed lower on Wednesday.

The S&P/BNY Mellon index of American depositary receipts ticked down 0.5% to 142.29. The European index edged down 0.3% to 138.01. The Asian index retreated 0.7% to 163.69. The Latin American index lost 0.4% to 185.22, while the emerging-markets index shed 1.1% to 277.99.

Amarin Corp. was among those whose ADRs traded actively.

The Dublin biopharmaceutical company slipped 1.7% after it said Switzerland's Swissmedic has granted approval for Amarin's fish-oil-derived drug Vazkepa.

Steelmaker ArcelorMittal SA edged down 0.6% after Itochu Corp. agreed to buy a 49.6% stake in a company that holds a 15% stake in a ArcelorMittal Canadian subsidiary.

 

Write to Denny Jacob at denny.jacob@wsj.com

 

(END) Dow Jones Newswires

December 07, 2022 18:07 ET (23:07 GMT)

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