FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

ANSTICE DAVID W
2. Issuer Name and Ticker or Trading Symbol

Alkermes plc. [ ALKS ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
_____ Officer (give title below)    _____ Other (specify below)
(Last)          (First)          (Middle)

CONNAUGHT HOUSE, 1 BURLINGTON ROAD
3. Date of Earliest Transaction (MM/DD/YYYY)

9/28/2020
(Street)

DUBLIN 4 IRELAND 
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares 9/28/2020 (1) M(2)  20000 A$14.92 86213 D  
Ordinary Shares 9/28/2020 (1) S(3)  17832 D$16.785 (4)68381 D  

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Non Qualified Stock Option (Right to Buy) $14.92 9/28/2020 (1) M (2)    20000   (5)10/5/2020 Ordinary Shares 20000 $0 0 D  

Explanation of Responses:
(1) Late filing due to technical error.
(2) This option exercise was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person.
(3) This sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person. This sale was made to cover the option exercise price and related fees.
(4) The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $16.72 to $16.87. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff upon request.
(5) These options are fully vested in accordance with their terms.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
ANSTICE DAVID W
CONNAUGHT HOUSE
1 BURLINGTON ROAD
DUBLIN 4 IRELAND 
X



Signatures
/s/ Shantale Greenson, attorney-in-fact for David W. Anstice10/5/2020
**Signature of Reporting PersonDate

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