Agios to Present Clinical Data from its IDH Program at ASCO

Date : 05/15/2019 @ 9:05PM
Source : GlobeNewswire Inc.
Stock : Agios Pharmaceuticals, Inc. (AGIO)
Quote : 47.96  0.0 (0.00%) @ 1:00AM

Agios to Present Clinical Data from its IDH Program at ASCO

AGIOS PHARMACEUTICALS INC (NASDAQ:AGIO)
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Agios Pharmaceuticals, Inc. (NASDAQ:AGIO), a leader in the field of cellular metabolism to treat cancer and rare genetic diseases, today announced that data from its isocitrate dehydrogenase (IDH) programs will be presented at the American Society of Clinical Oncology (ASCO) Annual Meeting being held May 31-June 4, 2019 in Chicago.

The accepted abstracts are listed below and are available online on the ASCO conference website: http://abstracts.asco.org/.

Oral Presentation:

Title: A phase 1, open label, perioperative study of AG-120 and AG-881 in recurrent IDH1 mutant, low-grade glioma: Results from cohort 1Date & Time: Monday, June 3, 2019 from 2:15-2:27 p.m. CTOral Abstract Session: Central Nervous System TumorsAbstract: 2003Location: S102Presenter: Ingo K. Mellinghoff, M.D., Memorial Sloan Kettering Cancer Center

Poster Presentations:

Title: Ivosidenib (IVO; AG-120) in IDH1-mutant newly diagnosed acute myeloid leukemia (ND AML): Updated results from a phase 1 studyPoster Session Date & Time: Monday, June 3, 2019 from 8:00-11:00 a.m. CTPoster Session: Hematologic Malignancies – Leukemia, Myelodysplastic Syndromes, and Allotransplant Abstract: 7028Poster Board: 403Poster Location: Hall AAuthor: Gail J. Roboz, M.D., Weill Medical College of Cornell University

Title: Mutant IDH1 inhibitor ivosidenib (IVO; AG-120) in combination with azacitidine (AZA) for newly diagnosed acute myeloid leukemia (ND AML)Poster Session Date & Time: Monday, June 3, 2019 from 1:15-4:15 p.m. CTPoster Session: Hematologic Malignancies – Leukemia, Myelodysplastic Syndromes, and AllotransplantAbstract: 7011Poster Board: 386Poster Location: Hall AAuthor: Courtney D. DiNardo, M.D., University of Texas MD Anderson Cancer Center

About AgiosAgios is focused on discovering and developing novel investigational medicines to treat cancer and rare genetic diseases through scientific leadership in the field of cellular metabolism and adjacent areas of biology. In addition to an active research and discovery pipeline across both therapeutic areas, Agios has two approved oncology precision medicines and multiple first-in-class investigational therapies in clinical and/or preclinical development. All Agios programs focus on genetically identified patient populations, leveraging our knowledge of metabolism, biology and genomics. For more information, please visit the company's website at www.agios.com.

Cautionary Note Regarding Forward-Looking StatementsThis press release contains forward-looking statements within the meaning of The Private Securities Litigation Reform Act of 1995. Such forward-looking statements include those regarding the potential benefits of Agios' products and product candidates, including TIBSOVO® (ivosidenib) and vorasidenib (AG-881); its plans regarding future data presentations; and the potential benefit of its strategic plans and focus. The words “anticipate,” “expect,” “intend,” “potential,” “upcoming,” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Such statements are subject to numerous important factors, risks and uncertainties that may cause actual events or results to differ materially from Agios' current expectations and beliefs. For example, there can be no guarantee that any product candidate Agios or its collaborators are developing will successfully commence or complete necessary preclinical and clinical development phases, or that development of any of Agios' product candidates will successfully continue. Moreover, there can be no guarantee that the two approved oncology precision medicines being commercialized by Agios and/or its collaborators will receive commercial acceptance. There can be no guarantee that any positive developments in Agios' business will result in stock price appreciation. Management's expectations and, therefore, any forward-looking statements in this press release could also be affected by risks and uncertainties relating to a number of other important factors, including: Agios' results of clinical trials and preclinical studies, including subsequent analysis of existing data and new data received from ongoing and future studies; the content and timing of decisions made by the U.S. FDA and other regulatory authorities, investigational review boards at clinical trial sites and publication review bodies; Agios' ability to obtain and maintain requisite regulatory approvals and to enroll patients in its planned clinical trials; unplanned cash requirements and expenditures; competitive factors; Agios' ability to obtain, maintain and enforce patent and other intellectual property protection for any product candidates it is developing; Agios' ability to maintain key collaborations; and general economic and market conditions. These and other risks are described in greater detail under the caption "Risk Factors" included in Agios’ public filings with the Securities and Exchange Commission. Any forward-looking statements contained in this press release speak only as of the date hereof, and Agios expressly disclaims any obligation to update any forward-looking statements, whether as a result of new information, future events or otherwise, except as required by law.            Contacts

Investor & Media ContactHolly Manning, 617-844-6630Associate Director, Investor RelationsHolly.Manning@agios.com

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