FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      
1. Name and Address of Reporting Person * Weiss Asset Management LP 2. Date of Event Requiring Statement (MM/DD/YYYY)
9/29/2020 

3. Issuer Name and Ticker or Trading Symbol Pfenex Inc. [PFNX]
(Last)       (First)       (Middle)
222 BERKELEY STREET, 16TH FLOOR
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)_____ Director                          ___X___ 10% Owner
_____ Officer (give title below)        _____ Other (specify below)
(Street)
BOSTON, MA 02116      
(City)             (State)             (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
 

6. Individual or Joint/Group Filing(Check Applicable Line)___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock  4320055 (1) I  See Footnote 1 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
(1)  Shares reported herein represent shares beneficially owned by two private investment funds for which Weiss Asset Management LP serves as investment manager. WAM GP LLC is the general partner of Weiss Asset Management LP and Andrew Weiss is the Managing Member of WAM GP LLC. All of Weiss Asset Management LP, WAM GP LLC, and Andrew Weiss disclaim beneficial ownership of the shares reported herein except to the extent of their pecuniary interest therein.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Weiss Asset Management LP
222 BERKELEY STREET, 16TH FLOOR
BOSTON, MA 02116

X

WEISS ANDREW M
222 BERKELEY STREET, 16TH FLOOR
BOSTON, MA 02116

X

WAM GP LLC
222 BERKELEY STREET, 16TH FLOOR
BOSTON, MA 02116

X


Signatures
Georgiy Nikitin, Chief Compliance Officer, Weiss Asset Management LP and WAM GP LLC 9/30/2020
**Signature of Reporting Person Date
Georgiy Nikitin, duly authorized under a power of attorney by Andrew M. Weiss 9/30/2020
**Signature of Reporting Person Date