UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

__________________________________

FORM 6-K
 
__________________________________
 
Report of Foreign Private Issuer
Pursuant to Rule 13a-16 or 15d-16 under
the Securities Exchange Act of 1934
For the quarterly period ended June 30, 2022
Commission File Number 001-38332
 __________________________________
QIAGEN N.V.
(Translation of registrant’s name into English)
 __________________________________
Hulsterweg 82
5912 PL Venlo
The Netherlands
__________________________________
 
Indicate by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F.
Form 20-F  ý            Form 40-F  o
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1):  o
Indicate by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7):  o


QIAGEN N.V.
Form 6-K

TABLE OF CONTENTS
 
ItemPage
Other Information
Signatures
Exhibit Index

2
OTHER INFORMATION
On July 26, 2022, QIAGEN N.V. (NYSE: QGEN; Frankfurt, Prime Standard: QIA) issued a press release announcing its unaudited financial results for the period ended June 30, 2022. The press release is furnished herewith as Exhibit 99.1 and is incorporated by reference herein.
QIAGEN has regularly reported adjusted results, which are considered non-GAAP financial measures, to give additional insight into our financial performance as a supplement to understand, manage, and evaluate our business results and make operating decisions. We also use the adjusted results when comparing to our historical operating results, which have consistently been presented on an adjusted basis.
Adjusted results should be considered in addition to the reported results prepared in accordance with U.S. generally accepted accounting principles, but should not be considered as a substitute. Reconciliations of reported results to adjusted results are included in the tables accompanying the press release. We believe certain items should be excluded from adjusted results when they are outside of our ongoing core operations, vary significantly from period to period, or affect the comparability of results with the Company’s competitors and our own prior periods.
The non-GAAP financial measures used in this press release are non-GAAP net sales, gross profit, operating income, pre-tax income, net income, tax rate and diluted earnings per share. These adjusted results exclude costs related to business integration, acquisition and restructuring related items, long-lived asset impairments, amortization of acquired intangible assets, non-cash interest expense charges as well as other special income and expense items. Management views these costs as not indicative of the profitability or cash flows of our ongoing or future operations and therefore considers the adjusted results as a supplement, and to be viewed in conjunction with, the reported GAAP results.
We use a measure of free cash flow to estimate the cash flow remaining after purchases of property, plant and equipment as required to maintain or expand our business. This measure provides us with supplemental information to assess our liquidity needs. We calculate free cash flow as net cash from operating activities less purchases of property, plant and equipment.
We also consider results on a constant currency basis. Our functional currency is the U.S. dollar and our subsidiaries’ functional currencies are the local currency of the respective countries in which they are headquartered. A significant portion of our revenues and expenses is denominated in euros and currencies other than the United States dollar. Management believes that analysis of constant currency period-over-period changes is useful because changes in exchange rates can affect the growth rate of net sales and expenses, potentially to a significant degree. Constant currency figures are calculated by translating the local currency actual results in the current period using the average exchange rates from the previous year’s respective period instead of the current period.
We use non-GAAP and constant currency financial measures internally in our planning, forecasting and reporting, as well as to measure and compensate our employees. We do not reconcile forward-looking non-GAAP financial measures to the corresponding GAAP measures due to the high variability and difficulty in making accurate forecasts and projections that are impacted by future decisions and actions. Accordingly, reconciliations of these forward-looking non-GAAP financial measures to the corresponding GAAP measures are not available without unreasonable effort. However, the actual amounts of these excluded items will have a significant impact on QIAGEN’s GAAP results.




3
SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
 
QIAGEN N.V.
By:/s/ Roland Sackers
 Roland Sackers
 Chief Financial Officer

Date: July 27, 2022

4
EXHIBIT INDEX
 
Exhibit
No.
  Exhibit
99.1  Press Release dated July 26, 2022


5
Exhibit 99.1
Media Release
qiagen_logo.jpg


QIAGEN beats outlook for Q2 2022 and raises full-year 2022 outlook

•Q2 2022: Net sales of $516 million (-9% actual rates, -4% CER); diluted EPS of $0.42 and adjusted diluted EPS of $0.51 over year-ago period

◦Net sales of $544 million at CER vs. outlook for at least $510 million CER, adjusted diluted EPS of $0.53 CER vs. outlook for at least $0.46 CER

◦Non-COVID sales rise 10% CER to $423 million, and up 15% CER excluding Q2 2021 genomics technology sale; COVID-19 sales decline 39% CER

•H1 2022 operating cash flow +33% to $379 million, free cash flow +63% to $318 million

•2022 net sales outlook raised to at least $2.2 billion CER, reaffirmed double-digit CER growth in non-COVID products; adj. diluted EPS outlook raised to at least $2.30 CER

Venlo, the Netherlands, July 26, 2022 - QIAGEN N.V. (NYSE: QGEN; Frankfurt Prime Standard: QIA) announced results for the second quarter of 2022 and increased the outlook for full-year 2022.

Net sales for Q2 2022 declined 9% (-4% at constant exchange rates, CER) to $516 million from Q2 2021. Sales at CER were $544 million, ahead of the outlook for at least $510 million CER. Sales were driven by 10% CER growth in the non-COVID-19 product portfolio to $423 million, but sales of COVID-19 products fell 39% CER to $92 million. Adjusted diluted earnings per share (EPS) were $0.51 ($0.53 CER) compared to $0.67 in Q2 2021, and ahead of the outlook for at least $0.46 CER.

Based on the strong performance in the first half of the year, QIAGEN has raised its full-year 2022 net sales outlook of at least $2.2 billion CER (prior outlook for at least $2.12 billion CER) and for adjusted diluted EPS of at least $2.30 CER (prior outlook for at least $2.14 CER). This update includes a reaffirmation of the goal for double-digit CER sales growth from the non-COVID product groups, which grew 12% CER in the first half of 2022, but for a decline in COVID-19 sales amid volatile pandemic trends. It also reflects a review of macro-economic trends, including inflation and energy supplies.

"QIAGEN continues to deliver in 2022, led by double-digit CER sales growth from our non-COVID product portfolio in the first half of the year as we steadily execute on our goals. These solid results give us renewed confidence to increase our full-year outlook for 2022 and position QIAGEN for solid growth beyond the COVID-19 pandemic," said Thierry Bernard, Chief Executive Officer of QIAGEN N.V. "We are addressing the challenges of the macro-environment with actions that include securing supply chains and energy needs. We are accelerating our focused strategy to enhance our balanced portfolio serving Life Science and Molecular Diagnostics customers worldwide, investing into our Five Pillars of Growth and remaining ready to support COVID-19 testing needs as they develop."

Roland Sackers, Chief Financial Officer of QIAGEN N.V., said: “Our results for the first half of 2022 in our non-COVID business are another confirmation of how QIAGEN is moving ahead from a position of strength to create and sustain our growth opportunities. In light of the strong operating cash flow, we are accelerating investments into our portfolio, especially R&D initiatives to expand the test menu on key automation systems. The acquisition of BLIRT S.A. is a reaffirmation of our disciplined capital deployment strategy as we seek various ways to create greater value for shareholders and our other stakeholders.”





6

Second quarter 2022 results

Key figures
In $ millions
(Except EPS and diluted shares)
Q2H1
20222021Change20222021Change
Net sales516567-9%1,1441,1351%
Net sales - CER544-4%1,1986%
Operating income122161-24%3293251%
Adjusted operating income146196-26%378391-3%
Net income97121-20%2522501%
Adjusted net income118155-24%303308-2%
Diluted EPS$0.42$0.52-19%$1.09$1.081%
Adjusted diluted EPS$0.51$0.67-24%$1.31$1.33-2%
Adjusted diluted EPS - CER$0.53-21%$1.362%
Diluted shares (in millions)230232230232
Please refer to accompanying tables for reconciliation of reported to adjusted figures.
Tables may have rounding differences. Percentage changes are to prior-year periods.


Sales by product type, customer class and non-COVID/COVID-19 product groups


Q2 2022H1 2022
Sales
(In $ m)		%
change		% CER change% of
sales		Sales
(In $ m)		% change% CER change% of
sales
Consumables and related revenues$453-9%-4%88%$1,014+2%+7%89%
Instruments$63-10%-5%12%$130-6%-2%11%
Molecular Diagnostics$255-6%0%49%$611+11%+18%53%
Life Sciences$261-12%-8%51%$533-9%-6%47%
Non-COVID product groups$423+4%+10%82%$823+7%+12%72%
COVID-19 product groups$92-42%-39%18%$321-12%-7%28%

•Sales: Non-COVID product group sales in Q2 2022 rose 10% CER over Q2 2021, and grew 15% CER excluding the $20 million genomics technology sale in the year-ago period. Excluding COVID-19 sales in Q2 2022, Molecular Diagnostics sales rose at a double-digit CER rate, while Life Science sales grew at a single-digit CER rate. Sales at actual rates declined 9% due to about five percentage points of adverse currency movements in Q2 2022 due to the strengthening of the U.S. dollar against the euro and other currencies.

•Operating income: Q2 2022 operating income margin was 23.7% of sales compared to 28.4% in the year-ago period. The adjusted operating income margin also declined to 28.4% from 34.6% in the year-ago period, reflecting lower sales contributions as well as investments into the Five Pillars of Growth. For Q2 2022, the adjusted gross margin was 67.4%, a decline of about 1.3 percentage points from Q2 2021, due mainly to production capacity expansion projects. R&D costs rose to 9.7% of sales from 9.2% in the year-ago period, with key investments into the Five Pillars of Growth. Sales & Marketing expenses rose about 3.6 percentage points to 23.1% of sales, due to a combination of investments into dedicated sales and marketing activities for the Five Pillars of Growth and higher freight costs. General & Administrative expenses rose about one percentage point to about 6.4% of sales, mainly for IT and cybersecurity investments.
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•EPS: Diluted EPS was $0.42 per share in Q2 2022 compared to $0.52 in Q2 2021. Adjusted diluted EPS of $0.52 ($0.53 CER) reflected a higher tax rate of 20% in Q2 2022 compared to 19% in the year-ago period.

Sales by product groups
Q2 2022H1 2022
Sales
(In $ m)		%
change		% CER change% of
sales		Sales
(In $ m)		% change% CER change% of
sales
Sample technologies$178-12%-7%35%$443+3%+8%39%
Diagnostic solutions$157+2%+7%30%$331+9%+14%29%
Of which QuantiFERON$83+15%+19%16%$161+25%+28%14%
Of which QIAstat-Dx$16+4%+11%3%$43+16%+22%4%
Of which NeuMoDx$18-18%-11%4%$45-16%-11%4%
Of which Other$40-11%-4%7%$82-3%+4%7%
PCR / Nucleic acid amplification$105-3%0%20%$221-2%+1%19%
Genomics / NGS$57-28%-23%11%$113-13%-8%10%
Other$19-17%-6%4%$35-22%-11%3%
Tables may have rounding differences. Percentage changes are to prior-year periods.

•Sample technologies: Sales in the non-COVID product groups rose 8% CER in Q2 2022 over the year-ago period and represented over 75% of product group sales over the year-ago period. Overall sales declined 7% CER due to the drop in COVID-19 testing demand. Instrument sales rose at a double-digit CER pace, led by strong sales trends for the EZ2 instrument and higher placements of QIAcube Connect.

•Diagnostic solutions: QuantiFERON-TB led the performance in Q2 2022 with 19% CER growth over the year-ago period, and led by double-digit CER gains in the Americas and Europe / Middle East /Africa regions. QIAstat-Dx sales grew at a double-digit CER pace on growth in consumables and was supported by new placements around the world. NeuMoDx sales remained in line with the full-year goal for about $80 million CER of sales with reduced demand for COVID-19 testing. Revenues from companion diagnostic co-development projects were up 2% CER to $10 million, while sales of Precision Medicine companion diagnostics rose at a low-single-digit CER rate over Q2 2021.

•PCR / Nucleic acid amplification: Sales at CER were largely unchanged as double-digit CER growth in non-COVID products was offset by the decline in COVID-19 product group sales. Sales of the QIAcuity digital PCR system rose at a strong double-digit CER rate, founded on a growing installed base and improvements in consumables utilization rates.

•Genomics / NGS: Sales were up 2% CER in Q2 2022 excluding the year-ago impact of the genomics technology sale. Non-COVID product group sales rose at a single-digit CER rate thanks to solid growth in universal NGS consumables that more than offset a low-single-digit CER decline in sales from the QIAGEN Digital Insights bioinformatics business.

8

Sales by geographic regions
Q2 2022H1 2022
Sales
(In $ m)		%
change		% CER change% of
sales		Sales
(In $ m)		% change% CER change% of
sales
Americas$252-2%-1%49%$505+1%+1%44%
Europe / Middle East / Africa$161-21%-10%31%$410-3%+8%36%
Asia-Pacific / Japan$102-6%0%20%$229+7%+12%20%
Tables may have rounding differences. Percentage changes are to prior-year periods.
Rest of world represented less than 1% of sales.

•Americas: The U.S. had largely unchanged sales compared to Q2 2021, as solid double-digit CER growth in the non-COVID product groups was offset by lower COVID-19 testing demand. Canada provided double-digit CER gains against lower CER sales in Brazil and Mexico.

•Europe / Middle East / Africa: Germany, Spain and the Netherlands maintained solid CER growth trends in Q2 2022, but sales declined in France, Switzerland and the United Kingdom compared to Q2 2021 and led to the overall regional decline.

•Asia-Pacific / Japan: Sales in China rose at a low-single-digit CER rate in Q2 2022 despite the lockdown measures. Australia and South Korea posted CER sales gains against a low-single-digit CER decline in Japan.

Key cash flow data
H1
In $ millions20222021Change
Net cash provided by operating activities37928533%
Purchases of property, plant and equipment(61)(90)-32%
Free cash flow31819563%
Net cash used in investing activities(558)(79)606%
Net cash provided by (used in) financing activities13(43)-129%

•Net cash from operating activities rose 33% in H1 2022 over the prior-year period, driven by the strong business expansion and supported by ongoing disciplined working capital. Free cash flow rose at a faster 63% pace over the same period in 2021, with lower purchases of property, plant and equipment in H1 2022 compared to the year-ago period that included significant investments to expand production capacity. As of June 30, 2022, cash and cash equivalents and short-term investments rose to $1.3 billion from $1.1 billion on December 31, 2021.

•Net cash used in investing activities in H1 2022 rose significantly to $558 million from $79 million in the first half of 2021. Key factors were the increase in net short-term investments to $428 million in H1 2022 compared to net investments of $18 million in H1 2021, along with a payment in Q2 2022 of $64 million for the acquisition of BLIRT S.A.

•Net cash provided by (used in) financing activities swung to proceeds in H1 2022 over net cash used in the year-ago period, which included $43 million of repayments for long-term debt.






9

QIAGEN Sample to Insight portfolio updates

Among recent developments in QIAGEN's Sample to Insight portfolio:

Sample technologies

•QIAxcel Connect was recently launched as an upgrade to the earlier generation of this nucleic acid analysis capillary electrophoresis (CE) instrument. QIAxcel Connect is used by customers to deliver insights into DNA or RNA sample quality or fragment sizes, and is also available with QIAsphere, a software solution that lets users manage instruments via an app.

Diagnostic solutions

•QIAstat-Dx Rise was launched as planned with a CE-marking to process new syndromic panels for respiratory, gastrointestinal and meningitis diseases that can test simultaneously for multiple pathogens from one sample. QIAstat-Dx Rise and its test cartridges are a closed system for hands-off sample preparation and processing. With a random access capacity to hold up to 18 different tests, it can provide diagnostic results for up to 56 tests in eight hours, and up to 160 tests per day by using eight analytical modules.

•A CE-IVD version of the NeuMoDx HSV 1/2 Quant Assay was launched for the quantification and differentiation of herpes simplex virus type 1 (HSV-1) DNA and/or herpes simplex virus type 2 (HSV-2). This new assay supports QIAGEN’s strategy to expand the test menu available for use on the NeuMoDx 96 and 288 Molecular Systems, which offer one of the broadest menus on the market now with 15 CE-IVD tests available.

PCR and nucleic acid amplification

•QIAcuity digital PCR reached a milestone with 1,000 cumulative placements since launch in late 2020. QIAGEN also recently launched 13 new kits and assays for use in the biopharmaceuticals sector that allow quantification of AAV viral titer and residual host cell DNA in cell and gene therapy. This menu expansion now enables biopharma customers to benefit from a turnkey workflow for the development and manufacturing of cell and gene therapies.

QIAGEN acquires BLIRT S.A.

In May 2022, QIAGEN acquired BLIRT S.A., a supplier of standardized and customized solutions for proteins and enzymes as well as molecular biology reagents. Its offering includes proteins and enzymes that are critical to the life sciences industry and diagnostic kit manufacturers. BLIRT was founded in 1994 in Gdansk, Poland, has about 90 employees and reported less than $10 million sales in 2021.

New member elected to the Supervisory Board

Dr. Eva Pisa was elected as a new member of the Supervisory Board at the Annual General Meeting on June 23, 2022, bringing the total number of Supervisory Board members to eight. Dr. Pisa contributes significant leadership experience in the life science and molecular diagnostics industries, and currently serves as an industry consultant. From 2001 to 2007, she served as CEO of Sangtec Molecular Diagnostics AB, a Swedish molecular diagnostic start-up that was acquired by Cepheid. She then worked for Roche Diagnostics International from 2007 to 2020. During her tenure, the Roche cobas 6800 / 8800 System was developed and launched. Dr. Pisa also served as Senior Vice President at Roche Centralized and POC Solutions, where she was responsible for Clinical Chemistry, Endocrinology and Custom Biotech (B2B business). She holds a Ph.D. from the Karolinska Institute in Sweden and an MBA from Heriot-Watt University in Scotland.


10

Supporting the global response to the monkeypox outbreak

QIAGEN teams around the world are working with local healthcare authorities to support testing needs for the monkeypox virus outbreak. QIAGEN's Sample technology kits and instruments are being used in the validated protocols of the U.S. Centers for Disease Control (CDC) for monkeypox testing, building on their use in other CDC-validated protocols, as well as in the emergency protocols of other countries around the world. Additionally, the NeuMoDx clinical PCR system offers the ability to process lab-developed tests (LDTs), and QIAGEN is working on adding the monkeypox virus to its QIAstat-Dx syndromic panel for meningitis diseases. The COVID-19 pandemic has also demonstrated the value of digital PCR through QIAcuity for the detection of disease in wastewater surveillance as a CDC-endorsed technology, and can be used for monkeypox surveillance as well. QIAGEN will continue to closely monitor the development of this outbreak in order to serve countries around the world in their testing needs.

QIAGEN ESG update

The environmentally friendly QIAwave nucleic-acid extraction kits have received the ACT (Accountability, Consistency, and Transparency) Environmental Impact Factor Label from My Green Lab, a non-profit organization dedicated to advancing sustainability in scientific research. QIAGEN launched the first kits in the QIAwave portfolio in January 2022 with the QIAwave RNA Mini Kit, QIAwave DNA Blood & Tissue Kit and QIAwave Plasmid Miniprep Kit. These kits are designed to use up to 63% less plastic and up to 42% less cardboard than other QIAGEN kits.

Outlook

For full-year 2022, QIAGEN has increased the outlook for net sales to at least $2.2 billion CER (prior outlook for at least $2.12 billion CER) and for adjusted diluted EPS to at least $2.30 CER per share (prior outlook for at least $2.14 CER). This update includes a reaffirmation of the goal for double-digit CER sales growth from the non-COVID product groups, which grew 12% CER in the first half of 2022, but for a decline in COVID-19 sales amid volatile pandemic trends. It also reflects an updated review of macro-economic issues, including inflation and energy supplies. Also taken into consideration is the adverse impact on sales resulting from the war in Ukraine, and related decisions to suspend business in Russia and Belarus (which represented about 1% of total QIAGEN sales in 2021). QIAGEN continues to make significant investments into its portfolio, in particular the Five Pillars of Growth, for new products, test menu and applications. The outlook does not take into consideration any future acquisitions.

Based on exchange rates as of July 25, 2022, currency movements against the U.S. dollar are now expected to create for full-year an adverse impact of about five percentage points on net sales and an adverse impact of about $0.10-0.11 per share on adjusted EPS.

For Q3 2022, net sales are expected to be at least $510 million CER compared to $535 million in Q3 2021, while adjusted EPS is expected to be at least $0.48 CER per share compared to $0.58 in the year-ago period.

Based on exchange rates as of July 25, 2022, currency movements against the U.S. dollar are expected to have an adverse impact for Q3 2022 on sales of about six percentage points and an adverse impact of $0.02-0.03 per share on adjusted EPS.
Investor presentation and conference call

A conference call is planned for Thursday, July 28, at 15:30 Frankfurt Time / 14:30 London Time / 9:30 New York Time. A live audio webcast will be made available in the investor relations section of the QIAGEN website, and a replay will also be made available after the event. A presentation is planned to be available shortly before the conference call at https://corporate.qiagen.com/investor-relations/events-and-presentations/default.aspx.

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Use of adjusted results

QIAGEN reports adjusted results, as well as results on a constant exchange rate (CER) basis, and other non-U.S. GAAP figures (generally accepted accounting principles), to provide additional insight into its performance. These results include adjusted net sales, adjusted gross income, adjusted gross profit, adjusted operating income, adjusted operating expenses, adjusted operating income margin, adjusted net income, adjusted net income before taxes, adjusted diluted EPS, adjusted EBITDA, adjusted EPS, adjusted income taxes, adjusted tax rate, and free cash flow. Free cash flow is calculated by deducting capital expenditures for Property, Plant & Equipment from cash flow from operating activities. Adjusted results are non-GAAP financial measures that QIAGEN believes should be considered in addition to reported results prepared in accordance with GAAP but should not be considered as a substitute. QIAGEN believes certain items should be excluded from adjusted results when they are outside of ongoing core operations, vary significantly from period to period, or affect the comparability of results with competitors and its own prior periods. Furthermore, QIAGEN uses non-GAAP and constant currency financial measures internally in planning, forecasting and reporting, as well as to measure and compensate employees. QIAGEN also uses adjusted results when comparing current performance to historical operating results, which have consistently been presented on an adjusted basis.

About QIAGEN

QIAGEN N.V., a Netherlands-based holding company, is the leading global provider of Sample to Insight solutions that enable customers to gain valuable molecular insights from samples containing the building blocks of life. Our sample technologies isolate and process DNA, RNA and proteins from blood, tissue and other materials. Assay technologies make these biomolecules visible and ready for analysis. Bioinformatics software and knowledge bases interpret data to report relevant, actionable insights. Automation solutions tie these together in seamless and cost-effective workflows. QIAGEN provides solutions to more than 500,000 customers around the world in Molecular Diagnostics (human healthcare) and Life Sciences (academia, pharma R&D and industrial applications, primarily forensics). As of June 30, 2022, QIAGEN employed more than 6,100 people in over 35 locations worldwide. Further information can be found at http://www.qiagen.com.

Forward-Looking Statement

Certain statements contained in this press release may be considered forward-looking statements within the meaning of Section 27A of the U.S. Securities Act of 1933, as amended, and Section 21E of the U.S. Securities Exchange Act of 1934, as amended. To the extent that any of the statements contained herein relating to QIAGEN's products, including those products used in the response to the COVID-19 pandemic, timing for launch and development, marketing and/or regulatory approvals, financial and operational outlook, growth and expansion, collaborations, markets, strategy or operating results, including without limitation its expected adjusted net sales and adjusted diluted earnings results, are forward-looking, such statements are based on current expectations and assumptions that involve a number of uncertainties and risks. Such uncertainties and risks include, but are not limited to, risks associated with management of growth and international operations (including the effects of currency fluctuations, regulatory processes and dependence on logistics), variability of operating results and allocations between customer classes, the commercial development of markets for our products to customers in academia, pharma, applied testing and molecular diagnostics; changing relationships with customers, suppliers and strategic partners; competition; rapid or unexpected changes in technologies; fluctuations in demand for QIAGEN's products (including fluctuations due to general economic conditions, the level and timing of customers' funding, budgets and other factors); our ability to obtain regulatory approval of our products; difficulties in successfully adapting QIAGEN's products to integrated solutions and producing such products; the ability of QIAGEN to identify and develop new products and to differentiate and protect our products from competitors' products; market acceptance of QIAGEN's new products and the integration of acquired technologies and businesses; actions of governments, global or regional economic developments, weather or transportation delays, natural disasters, political or public health crises, including the breadth and duration of the COVID-19 pandemic and its impact on the demand for our products and other aspects of our business, or other force majeure events; as well as the possibility that expected benefits related to recent or pending acquisitions may not materialize as expected; and the other factors discussed under the heading “Risk Factors” contained in Item 3 of our most recent Annual Report on Form 20-F. For further information, please
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refer to the discussions in reports that QIAGEN has filed with, or furnished to, the U.S. Securities and Exchange Commission.

Contacts

John Gilardi
Vice President Corporate Communications and Investor Relations
+49 2103 29 1171 and +49 152 018 11711 and +1 240 686 2222 / john.gilardi@qiagen.com

Phoebe Loh
Senior Director Investor Relations
+49 2103 29 11457 / phoebe.loh@qiagen.com

Dr. Thomas Theuringer
Senior Director, Head of External Communications
+49 2103 29 11826 / thomas.theuringer@qiagen.com

13


QIAGEN N.V.
CONDENSED CONSOLIDATED STATEMENTS OF INCOME
(unaudited)
Three monthsSix months
ended June 30,ended June 30,
(In $ thousands, except per share data)2022202120222021
Net sales515,512 567,308 1,143,903 1,134,514 
Cost of sales:
Cost of sales169,381 180,388 367,499 359,362 
Acquisition-related intangible amortization15,113 17,732 30,416 35,373 
Total cost of sales184,494 198,120 397,915 394,735 
Gross profit331,018 369,188 745,988 739,779 
Operating expenses:
Research and development49,896 52,150 96,272 99,583 
Sales and marketing118,890 110,394 237,394 224,154 
General and administrative32,528 31,018 66,878 64,821 
Acquisition-related intangible amortization2,799 5,320 5,716 10,728 
Restructuring, acquisition, integration and other, net4,748 9,035 10,500 15,424 
Total operating expenses208,861 207,917 416,760 414,710 
Income from operations122,157 161,271 329,228 325,069 
Other income (expense):
Interest income4,338 2,093 6,560 3,711 
Interest expense(13,659)(13,907)(27,195)(27,445)
Other income, net2,688 442 2,453 7,664 
Total other expense, net(6,633)(11,372)(18,182)(16,070)
Income before income taxes115,524 149,899 311,046 308,999 
Income tax expense18,863 28,848 59,073 58,725 
Net income96,661 121,051 251,973 250,274 
Diluted net income per common share$0.42 $0.52 $1.09 $1.08 
Diluted net income per common share (adjusted)$0.51 $0.67 $1.31 $1.33 
Shares used in computing diluted net income per common share (adjusted)229,938 231,950 230,229 232,122 













14

QIAGEN N.V.
RECONCILIATION OF REPORTED TO ADJUSTED FIGURES
(In $ millions, except EPS data)
(unaudited)

Three months ended June 30, 2022
Net 
Sales		Gross 
Profit		Operating
Income		Pre-tax
Income		Income 
Tax		Tax RateNet
Income		Diluted EPS*
Reported results515.5 331.0 122.2 115.5 (18.9)16%96.7 $0.42 
Adjustments:
Business integration, acquisition and restructuring related items (a)— 1.4 6.1 5.8 (1.5)4.2 0.02 
Purchased intangibles amortization (b)— 15.1 17.9 17.9 (4.4)13.5 0.06 
Non-cash interest expense charges (d)— — — 8.0 — 8.0 0.03 
Non-cash other income, net (e)— — — 0.2 — 0.2 0.00 
Certain income tax items (f)— — — — (4.4)(4.4)(0.02)
Total adjustments— 16.5 24.0 31.9 (10.3)21.5 0.09 
Adjusted results515.5 347.5 146.2 147.4 (29.2)20%118.2 $0.51 
*Using 229.9 M diluted shares    

 
Three months ended June 30, 2021
Net 
Sales		Gross 
Profit		Operating
Income		Pre-tax
Income		Income 
Tax		Tax RateNet
Income		Diluted EPS*
Reported results567.3 369.2 161.3 149.9 (28.8)19%121.1 $0.52 
Adjustments:
Business integration, acquisition and restructuring related items (a)— 3.0 12.1 11.8 (2.9)8.9 0.04 
Purchased intangibles amortization (b)— 17.7 23.1 23.1 (5.8)17.2 0.07 
Investment related gain, net (c)— — — (0.1)0.1 — 0.00 
Non-cash interest expense charges (d)— — — 7.7 — 7.7 0.03 
Non-cash other income, net (e)— — — (0.4)— (0.4)0.00 
Certain income tax items (f)— — — — 0.2 0.2 0.00 
Total adjustments— 20.7 35.1 42.0 (8.4)33.6 0.14 
Adjusted results567.3 389.9 196.4 191.9 (37.2)19%154.7 $0.67 
*Using 231.9 M diluted shares



Please see footnotes for these tables on the following page.



15

QIAGEN N.V.
RECONCILIATION OF REPORTED TO ADJUSTED FIGURES
(In $ millions, except EPS data)
(unaudited)
Six months ended June 30, 2022
Net 
Sales		Gross 
Profit		Operating
Income		Pre-tax
Income		Income 
Tax		Tax RateNet 
Income		Diluted EPS*
Reported results1,143.9 746.0 329.2 311.0 (59.1)19%252.0 $1.09 
Adjustments:
Business integration, acquisition and restructuring related items (a)— 2.0 12.5 12.2 (3.2)9.0 0.04 
Purchased intangibles amortization (b)— 30.4 36.1 36.1 (8.9)27.2 0.12 
Non-cash interest expense charges (d)— — — 15.9 — 15.9 0.07 
Non-cash other income, net (e)— — — 0.2 — 0.2 0.00 
Certain income tax items (f)— — — — (1.8)(1.8)(0.01)
Total adjustments— 32.4 48.6 64.5 (13.9)50.6 0.22 
Adjusted results1,143.9 778.4 377.8 375.5 (73.0)19%302.6 $1.31 
*Using 230.2 M diluted shares
Six months ended June 30, 2021
Net 
Sales		Gross 
Profit		Operating
Income		Pre-tax
Income		Income 
Tax		Tax RateNet
Income		Diluted EPS*
Reported results1,134.5 739.8 325.1 309.0 (58.7)19%250.3 $1.08 
Adjustments:
Business integration, acquisition and restructuring related items (a)— 4.5 19.9 20.0 (4.6)15.4 0.07 
Purchased intangible amortization (b)— 35.4 46.1 46.1 (11.7)34.4 0.15 
Investment related gain, net (c)— — — (6.6)1.6 (5.0)(0.02)
Non-cash interest expense charges (d)— — — 15.3 — 15.3 0.07 
Non-cash other income, net (e)— — — (1.0)— (1.0)0.00 
Certain income tax items (f)— — — — (0.8)(0.8)0.00 
Total adjustments— 39.9 66.0 73.7 (15.5)58.2 0.25 
Adjusted results1,134.5 779.6 391.1 382.7 (74.3)19%308.5 $1.33
*Using 232.1 M diluted shares

(a) Results for 2022 include costs for acquisition projects, including continued integration activities at NeuMoDx, as well as costs and impairments related to our business in Russia, Ukraine and Belarus, and the Q2 2022 acquisition of BLIRT S.A. Results for 2021 include integration costs for the NeuMoDx acquisition completed in September 2020. A restructuring program was initiated in late 2019, and charges were incurred through the end of 2021.
(b) The net decrease reflects the full amortization during 2021 of certain assets previously acquired, but partially offset by amortization related to the acquisition of BLIRT S.A. in Q2 2022.
(c) Amounts include mark-to-market adjustments and gains or losses recognized upon the sale or impairment of investments. Results for 2021 include the Q1 2021 gain on the sale of shares held in Invitae Corporation received from Invitae's acquisition of ArcherDX, in which QIAGEN held a minority interest, and settlement of the related hedge.
(d) Cash Convertible Notes were recorded at an original issue discount that is recognized as incremental non-cash interest expense over the expected life of the notes.
(e) Adjustment for the net impact of changes in fair value of the Call Options and the Embedded Cash Conversion Options related to the Cash Convertible Notes.
(f) This includes the impact of the estimated annual effective tax rate applied to the pretax amount in order to calculate the non-GAAP provision for income taxes. Additionally, certain income tax items were excluded from adjusted results since these represent updates in QIAGEN's assessment of ongoing examinations or other tax items that are not indicative of the Company's normal or future income tax expense. QIAGEN does not believe the impact of these events reflects the performance of ongoing operations for the periods in which the impact of such events were recorded.


Tables may contain rounding differences.

16

QIAGEN N.V.
CONDENSED CONSOLIDATED BALANCE SHEETS

(In $ thousands, except par value)June 30, 2022December 31, 2021
Assets(unaudited)
Current assets:
Cash and cash equivalents706,534 880,516 
Short-term investments604,429 184,785 
Accounts receivable, net334,573 362,131 
Inventories, net322,831 327,525 
Prepaid expenses and other current assets176,730 354,645 
Total current assets2,145,097 2,109,602 
Long-term assets:
Property, plant and equipment, net619,192 638,183 
Goodwill2,341,123 2,350,763 
Intangible assets, net594,439 627,436 
Fair value of derivative instruments235,315 190,430 
Other long-term assets148,277 157,644 
Deferred income tax assets70,242 72,896 
Total long-term assets4,008,588 4,037,352 
Total assets6,153,685 6,146,954 
Liabilities and Equity
Current liabilities:
Current portion of long-term debt460,267 847,626 
Accrued and other current liabilities417,442 568,620 
Accounts payable85,195 101,224 
Total current liabilities962,904 1,517,470 
Long-term liabilities:
Long-term debt, net of current portion1,475,255 1,094,144 
Fair value of derivative instruments223,168 191,879 
Other long-term liabilities175,354 209,320 
Deferred income tax liabilities34,593 37,591 
Total long-term liabilities1,908,370 1,532,934 
Equity:
Common shares, EUR .01 par value: Authorized - 410,000 shares, issued - 230,829 shares 2,702 2,702 
Additional paid-in capital1,841,757 1,818,508 
Retained earnings1,990,596 1,791,740 
Accumulated other comprehensive loss(391,421)(326,670)
       Less treasury stock, at cost — 3,135 and 3,755 shares in 2022 and 2021, respectively
(161,223)(189,730)
Total equity3,282,411 3,096,550 
Total liabilities and equity6,153,685 6,146,954 

17


QIAGEN N.V.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(unaudited)
 Six months ended June 30,
(In $ thousands)
20222021
Cash flows from operating activities:
Net income251,973 250,274 
Adjustments to reconcile net income to net cash provided by operating activities, net of effects of businesses acquired:
Depreciation and amortization103,408 110,669 
Non-cash impairments153 — 
Deferred income taxes(3,950)(30,993)
Amortization of debt discount and issuance costs16,650 15,986 
Share-based compensation expense23,249 19,297 
Other items, net including fair value changes in derivatives7,467 4,913 
Change in operating assets, net(13,299)(62,749)
Change in operating liabilities, net(6,288)(22,371)
Net cash provided by operating activities379,363 285,026 
Cash flows from investing activities:
Purchases of property, plant and equipment(61,367)(90,001)
Purchases of intangible assets(14,657)(11,253)
Purchases of investments, net(958)(1,645)
Cash paid for acquisitions, net of cash acquired(63,651)— 
Purchases of short-term investments(653,114)(136,683)
Proceeds from sales of short-term investments224,751 117,967 
Cash received for collateral asset11,100 42,890 
Other investing activities107 43 
Net cash used in investing activities(557,789)(78,682)
Cash flows from financing activities:
Repayment of long-term debt— (41,345)
Proceeds from issuance of common shares106 2,714 
Tax withholding related to vesting of stock awards(16,684)(13,291)
Cash paid for contingent consideration(4,572)— 
Cash received for collateral liability33,699 10,100 
Other financing activities— (1,656)
Net cash provided by (used in) financing activities12,549 (43,478)
Effect of exchange rate changes on cash and cash equivalents(8,105)(1,803)
Net (decrease) increase in cash and cash equivalents(173,982)161,063 
Cash and cash equivalents, beginning of period880,516 597,984 
Cash and cash equivalents, end of period706,534 759,047 
Reconciliation of Free Cash Flow(1)
Net cash provided by operating activities379,363 285,026 
Purchases of property, plant and equipment(61,367)(90,001)
Free Cash Flow317,996 195,025 
(1) Free cash flow is a non-GAAP financial measure and is calculated from cash provided by operations reduced by purchases of property, plant and equipment. QIAGEN believes this is a common financial measure useful to further evaluate the results of operations.
18
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