ITEM 6.
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INDEMNIFICATION OF DIRECTORS AND OFFICERS.
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Pursuant to the Registrants memorandum and articles of association, as amended, subject to the provisions of and so far as may be
permitted by the Irish Companies Act 2014, every director and secretary of the Registrant may be indemnified by the Registrant against all costs, charges, losses, expenses and liabilities incurred by him or her in the execution and discharge of his
or her duties or in relation thereto, including any liability incurred by him or her in defending civil or criminal proceedings which relate to anything done or omitted or alleged to have been done or omitted by him or her as a director, secretary,
executive or employee of the Registrant and in which judgment is given in his or her favor (or the proceedings are otherwise disposed of without any finding or admission of any material breach of duty on his part) or in which he or she is acquitted
or in connection with any application under any statute for relief from liability in respect of any such act or omission in which relief is granted to him or her by the Irish High Court.
Pursuant to the Registrants memorandum and articles of association, as amended, subject to the provisions of, and so far as may be
permitted by the Irish Companies Act 2014, the Registrant shall indemnify any current or former executive officer of the Registrant (excluding any directors or secretary) or any person who is serving or has served at the request of the Registrant as
a director, executive or trustee of another company, joint venture, trust or other enterprise against expenses, including attorneys fees, judgments, fines and amounts paid in settlement actually and reasonably incurred by him or her in
connection with any threatened, pending or completed action, suit or proceeding, whether civil, criminal, administrative or investigative, other than an action by or in the right of the Registrant, to which she or he was, is, or is threatened to be
made a party by reason of the fact that she or he is or was such a director, executive or trustee, provided that the indemnity shall not extend to any matter which would render it void pursuant to the Irish Companies Act 2014. Under the
Registrants memorandum and articles of association, as amended, the Registrants current or former executive officers, however, will not be entitled to indemnification by the Registrant if they have been adjudged to be liable for their
own fraud or dishonesty in the performance of duties to the Registrant.
The Registrant has entered into indemnity agreements with each of
its directors, its secretary and persons designated as executive officers that require it to indemnify such persons against any and all expenses (including attorneys fees), witness fees, judgments, fines, penalties, settlements and other
amounts incurred (including expenses of a derivative action) in connection with any action, suit or proceeding or alternative dispute resolution mechanism, inquiry, hearing or investigation, whether threatened, pending or completed and whether
conducted by the Registrant or any other party, to which any such person may be made a party by reason of the fact that such person is or was a director, officer, employee, consultant, agent or fiduciary of the Registrant or any of its subsidiaries
or other affiliated enterprises, provided that such persons conduct did not constitute a breach of his or her duty of loyalty or other fiduciary duty to the Registrant or its shareholders, and was not an act or omission not in good faith or
which involved intentional misconduct or a knowing violation of laws. The indemnity agreements also set forth certain procedures that will apply in the event of a claim for indemnification thereunder. The indemnity agreements with certain of the
Registrants directors further provide that, with respect to a director that is serving on the Registrants board of directors at the direction of a venture or other investment fund or entity, with respect to such indemnitees service
as a director, officer, employee, agent and/or fiduciary of the Registrant, the Registrants obligations under the indemnity agreement are the primary source of indemnification and advancement, the Registrant is required to make all expense
advances, and the Registrant is liable for all of such indemnitees expenses, to the extent required by the indemnity agreement and the Registrants memorandum and articles of association, without regard to any rights the indemnitee may
have against the applicable venture or other investment fund or entity, and the Registrant irrevocably waives, relinquishes and releases any and all claims against the applicable venture or other investment fund or entity for contribution,
subrogation or any other recovery of any kind in connection with the Registrants obligations under the indemnity agreement.
The
Registrant maintains directors and officers liability insurance. The policy insures the Registrants directors, secretary and executives against unindemnified losses arising from certain wrongful acts in their capacities as
directors, secretary and executives, and reimburses the Registrant for those losses for which the Registrant has lawfully indemnified the directors, secretary and executives. The policy contains various exclusions, none of which will apply to any
offerings pursuant to this registration statement.
The Registrant is a party to an investor rights agreement that provides for
cross-indemnification in connection with registration of the Registrants ordinary shares on behalf of parties to such agreements, including selling shareholders that may be named in one or more supplements to the prospectus included in any
such registration statement.
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