FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

PORTNOY DAVID		 2. Issuer Name and Ticker or Trading Symbol

CRYO CELL INTERNATIONAL INC [ CCEL ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__X__ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Chairman, Co-CEO
(Last)          (First)          (Middle)

700 BROOKER CREEK BLVD, SUITE 1800		 3. Date of Earliest Transaction (MM/DD/YYYY)

1/8/2021
(Street)

OLDSMAR, FL 34677
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
 6. Individual or Joint/Group Filing (Check Applicable Line)

_X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock         91790 I By Spouse 
Common Stock         94426 I By 401K 
Common Stock 1/8/2021  P  1000 A$7.50 479272 D  
Common Stock         152724 I By Corporation (1)
Common Stock         15061 I as Custodian for Daughter 
Common Stock         9974 I As Custodian for Son 
Common Stock         59027 I By LLC (2)
Common Stock         199080 I By IRA 
Common Stock         55219 I By Corporation (3)
Common Stock         10783 I As Custodian for Son 
Common Stock         10783 I As Custodian for Son 
Common Stock         10783 I As Custodian for Son 
Common Stock         9122 I As Custodian for Daughter 

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)		2. Conversion or Exercise Price of Derivative Security3. Trans. Date3A. Deemed Execution Date, if any4. Trans. Code
(Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)		8. Price of Derivative Security
(Instr. 5)		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option $1.72           12/1/2011 12/1/2021 Common Stock 200000  200000 D  
Stock Option $2.90           8/31/2011 8/31/2021 Common Stock 100000  100000 D  
Stock Option $3.14           4/15/2016 (4)4/15/2026 Common Stock 70270  70270 D  
Stock Option $7.92           3/8/2013 (5)3/8/2023 Common Stock 23636  23636 D  
Stock Option $7.53           8/30/2019 (6)8/30/2029 Common Stock 26243  26243 D  
Stock Option $7.28           12/20/2019 (7)12/20/2029 Common Stock 23636  23636 D  
Explanation of Responses:
(1) Shares of Common Stock held by Partner Community, as to which David I. Portnoy may be deemed beneficial owner as the Chairman of the Board and Secretary and as the managing member of Mayim Management, LLC, which may exercise investment and voting discretion over such shares of Common Stock in accordance with the Investment Advisory Agreement.
(2) Shares of Common Stock held by Mayim Investment Limited Partnership as is David I. Portnoy my be deemed the beneficial owner as the managing member and owner of Mayim Management, LLC, which is the general partner of Mayim Management Limited Partnership, which is the general partner of Mayim Investment Limited Partnership.
(3) Shares of Common Stock held by uTIPu, Inc., as to which David I. Portnoy may be deemed the beneficial owner as the Chairman of the Board and Secretary.
(4) Stock options vest 1/3 on the date of grant, 1/3 on December 1, 2016 and 1/3 on December 1, 2017.
(5) Stock Options will vest 1/3 on the date of grant, 1/3 on December 1, 2018 and 1/3 on December 1, 2019.
(6) Stock options will vest 1/3 on the date of grant, 1/3 on December 1, 2019 and 1/3 on December 1, 2020.
(7) Stock options will vest 1/3 on the date of grant, 1/3 on December 1, 2020 and 1/3 on December 1, 2021.
Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
PORTNOY DAVID
700 BROOKER CREEK BLVD
SUITE 1800
OLDSMAR, FL 34677		X
Chairman, Co-CEO
Signatures
/s/ David Portnoy1/12/2021
**Signature of Reporting PersonDate