Statement of Changes in Beneficial Ownership (4)

FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^* McDonough John	2. Issuer Name and Ticker or Trading Symbol T2 Biosystems, Inc. [ TTOO ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below)
(Last) (First) (Middle) 101 HARTWELL AVE	3. Date of Earliest Transaction (MM/DD/YYYY) 1/8/2020
(Street) LEXINGTON, MA 02421 (City) (State) (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) _X _ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Common Stock	1/8/2020		M		16666	A	⁽¹⁾	470285 ⁽²⁾	D
Common Stock	1/8/2020		M		100000	A	⁽¹⁾	570285	D

*Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)*
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)			11. Nature of Indirect Beneficial Ownership (Instr. 4)
Performance Restricted Stock Units	⁽¹⁾	1/8/2020		D			326087	⁽³⁾	⁽³⁾	Common Stock	326087	$0.00	0	D
Restricted Stock Units	⁽¹⁾	1/8/2020		M			16666	⁽⁴⁾	⁽⁴⁾	Common Stock	16666	$0.00	0	D
Restricted Stock Units	⁽¹⁾	1/8/2020		M			100000	⁽⁴⁾	⁽⁴⁾	Common Stock	100000	$0.00	0	D

Explanation of Responses:
(1)	Each restricted stock unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.
(2)	Includes 5,399 shares acquired under the Issuer's employee stock purchase plan on May 15, 2019.
(3)	On March 15, 2018, the reporting person was granted Performance Restricted Stock Units that vest in the form of common stock based upon the achievement of certain pre-established 90-day average daily closing prices per share goals over a three year performance period. On January 8, 2020, the reporting person incurred a termination of service and forfeited the remaining unvested RSU's subject to this grant.
(4)	Pursuant to the terms of that certain Employment Agreement by and between the reporting person and Issuer, dated March 4, 2008, as amended by that certain First Amendment to Employment Agreement, dated July 7, 2014 and that certain Second Amendment to Employment Agreement, dated July 30, 2019, upon the reporting person's resignation as Chief Executive Officer, these RSUs automatically vested on January 8, 2020.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
McDonough John 101 HARTWELL AVE LEXINGTON, MA 02421	X