FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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OMB Number: 3235-0287
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Rosellini William 		2. Issuer Name and Ticker or Trading Symbol

NEXEON MEDSYSTEMS INC [ NXNN ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      __ X __ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
CHIEF EXECUTIVE OFFICER
(Last)          (First)          (Middle)

C/O NEXEON MEDSYSTEMS INC, 1910 PACIFIC AVENUE, SUITE 20000 		3. Date of Earliest Transaction (MM/DD/YYYY)

1/8/2019
(Street)

DALLAS, TX 75201
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   1/8/2019     G (1)    26500   (1) D   (1) 644527   I   Held by Rosellini Scientific Holdings, LLC  
Common Stock   1/8/2019     G (1)    19000   (1) D   (1) 625527   I   Held by Rosellini Scientific Holdings, LLC  
Common Stock   1/8/2019     G (1)    35000   (1) D   (1) 590527   I   Held by Rosellini Scientific Holdings, LLC  
Common Stock   1/8/2019     G (1)    402785   (1) D   (1) 187742   I   Held by Rosellini Scientific Holdings, LLC  

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
(1)  On January 8, 2019, Rosellini Scientific Holdings, LLC respectively gifted 26,500 shares of common stock of the Issuer to Elizabeth Rosellini, 19,000 shares to Michael Rosellini, 35,000 shares to Rosellini Family Irrevocable Trust UA Dated 09/24/2018, and 402,785 shares to Rosellini Family Irrv Tr 2.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Rosellini William
C/O NEXEON MEDSYSTEMS INC
1910 PACIFIC AVENUE, SUITE 20000
DALLAS, TX 75201 		X X CHIEF EXECUTIVE OFFICER
Rosellini Scientific Holdings, LLC
CORNER OF JEWS AND MARION
CHARLESTON, U7 
X


Signatures
/s/ William Rosellini 1/9/2019
** Signature of Reporting Person Date

/s/ William Rosellini, Sole Member / Manager of Rosellini Scientific Holdings, LLC 1/9/2019
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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