FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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OMB Number: 3235-0287
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Trieu Vuong 		2. Issuer Name and Ticker or Trading Symbol

Marina Biotech, Inc. [ MRNA ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

C/O AUTOTELIC LLC, 17870 CASTLETON STREET, SUITE 250 		3. Date of Earliest Transaction (MM/DD/YYYY)

10/1/2018
(Street)

CITY OF INDUSTRY, CA 91748
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   10/1/2018     D    500000   D $0.50   612716   D   (1)  
Common Stock                  2312355   I   See footnote   (2)
Common Stock                  525535   I   See footnote   (3)
Common Stock                  86207   I   See footnote   (4)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
(1)  Dr. Trieu also holds warrants to purchase 1,135,425 shares of common stock and 151.39 shares of Series E Convertible Preferred Stock (which shares are initially convertible into 1,513,900 shares of common stock).
(2)  Represents shares held by Autotelic LLC, of which entity the reporting person serves as Chief Executive Officer.
(3)  Represents shares held by Autotelic Inc., of which entity the reporting person serves as Chairman of the Board. Autotelic Inc. also holds warrants to purchase 2,706,965 shares of common stock and 181.59 shares of Series E Convertible Preferred Stock (which shares are initially convertible into 1,815,900 shares of common stock).
(4)  Represents shares held by LipoMedics, Inc., of which entity the reporting person serves as Chairman of the Board and Chief Operating Officer.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Trieu Vuong
C/O AUTOTELIC LLC
17870 CASTLETON STREET, SUITE 250
CITY OF INDUSTRY, CA 91748 		X X


Signatures
/s/ Vuong Trieu 10/4/2018
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.