LIFE aTyr Pharma Inc

Item 1.  Security and Issuer.

 This statement on Schedule 13D relates to the Common Stock of the Issuer.  The Issuer’s principal executive offices are located at 3545 John Hopkins Court, Suite #250, San Diego, CA 92121.

Item 2.  Identity and Background.

Prototype PSP is a profit sharing plan for the benefit of Dr. Schimmel.  Dr. Schimmel is the trustee of Prototype PSP.

Item 3.  Source or Amount of Funds or Other Consideration.

The share and dollar amounts reported below for transactions prior to August 7, 2007 do not give effect to the one-for-three stock split of Issuer’s Common Stock, Series A Preferred Stock and Series B Preferred Stock effected on August 7, 2007.  The share and dollar amounts reported below for transactions prior to May 5, 2015 do not give effect to the one-for-7.95413 reverse stock of Issuer’s Common Stock effected on May 5, 2015.  

On September 8, 2005, the Dr. Schimmel purchased 325,000 shares of restricted Common Stock (the “Common Shares”) at a purchase price of $0.01. per share which was the price per share paid by other founders in a private placement transaction.  On December 16, 2005, 32,000 of the Common Shares were gifted to certain individuals.  On July 17, 2006, 15,000 of the Common Shares were gifted to an individual.  On May 20, 2013, the remaining 278,000 Common Shares were transferred to the Schimmel Revocable Trust U/A Dtd 9/6/2000 (the “Schimmel Trust”).  

On September 8, 2005, Prototype PSP purchased 175,000 shares of Series A Convertible Preferred Stock (the “Series A Shares”) at a purchase price of $0.75 per share which was the price per share paid by other investors in a private placement transaction.  On May 20, 2013, the Series A Shares were transferred to the Schimmel Trust.  Upon completion of Issuer’s initial public offering (the “Offering”), the Series A Shares converted to 66,003 shares of Common Stock.

On November 30, 2006, Prototype PSP purchased 400,000 shares of Series B-1 convertible preferred stock (the “Series B-1 Shares”) at a purchase price of $2.50 per share which was the price per share paid by other investors in a private placement transaction.  On May 20, 2013, the Series B-1 Shares were transferred to the Schimmel Trust.  Upon completion of the Offering, the Series B-1 Shares converted to 150,865 shares of Common Stock.

On June 30, 2009, the Prototype PSP purchased 1,440,058 shares of Series B-2 convertible preferred stock (the “Series B-2 Shares”) at a purchase price of $0.8333 per share which was the price per share paid by other investors in a private placement transaction.  On May 20, 2013, the Series B-2 Shares were transferred to the Schimmel Trust.  Upon completion of the Offering, the Series B-2 Shares converted to 181,045 shares of Common Stock.  

On October 6, 2010, Prototype PSP purchased 239,361 shares of Series C convertible preferred stock (the “Prototype Series C Shares”) at a purchase price of $0.94 per share which was the price per share paid by other investors in a private placement transaction.  On May 20, 2013, the Prototype Series C Shares were transferred to the Schimmel Trust.  Upon completion of the Offering, the Prototype Series C shares converted to 30,093 shares of Common Stock.

On October 6, 2010, the Schimmel Trust purchased 212,765 shares of Series C convertible preferred stock (the “Series C Shares”) at a purchase price of $0.94 per share which was the price per share paid by other investors in a private placement transaction.  Upon completion of the Offering, the Series C Shares converted to 26,749 shares of Common Stock.

On December 21, 2011, Prototype PSP purchased 106,382 shares of Series C convertible preferred stock (the “Prototype Second Closing Series C Shares”) at a purchase price of $0.94 per share.  On May 20, 2013, the Prototype Second Closing Series C Shares were transferred to the Schimmel Trust. Upon completion of the Offering, the Prototype Second Closing Series C shares converted to 13,374 shares of Common Stock.

On September 13, 2012, Dr. Schimmel was granted an option to purchase 200,000 shares of Common Stock of the Issuer at a purchase price of $0.11 per share pursuant to the Company’s 2007 Stock Plan, as amended (subsequently amended and restated as the Issuer’s 2014 Stock Plan).  

On February 15, 2013, Dr. Schimmel exercised stock options for 200,000 shares of Common Stock (the “Option Shares”).  On March 1, 2013, the Option Shares were transferred to the Schimmel Trust.

On April 8, 2013, Prototype PSP purchased 248,024 shares of Series D redeemable convertible preferred stock (the “Prototype Series D Shares”) at a purchase price of $2.529 per share (payable with cash and cancellation of indebtedness) which was the price per share paid by other investors in a private placement transaction.  Upon completion of the Offering, the Prototype Series D shares converted to 31,181 shares of Common Stock.

On April 8, 2013, the Schimmel Trust purchased 15,031 shares of Series D redeemable convertible preferred stock (the “Series D Shares”) at a purchase price of $2.529 per share (payable with cash and cancellation of indebtedness) which was the price per share paid by other investors in a private placement transaction.  Upon completion of the Offering, the Series D Shares converted to 1,889 shares of Common Stock.

On July 10, 2014, Dr. Schimmel was granted an option to purchase 100,000 shares of Common Stock at a purchase price of $0.51 per share pursuant to the Issuer’s 2014 Stock Plan.  

On March 31, 2015 the Schimmel Trust purchased 446,827 shares of Series E redeemable convertible preferred stock (the “Series E Shares”) at a purchase price of $1.119 per share which was the price per paid by other investors in a private placement transaction.  Upon completion of the Offering, the Series E Shares converted to 46,154 shares of Common Stock.  

On April 2, 2015, Dr. Schimmel exercised stock options for 100,000 shares of Common Stock (the “O ption Shares”).  The Option Shares were subsequently transferred to the Schimmel Trust.

On April 25, 2015, Dr. Schimmel was granted an option to purchase 56,000 shares of Common Stock at a purchase price of $1.15 per share pursuant to the Issuer’s 2014 Stock Plan.

On July 8, 2015, Dr. Schimmel was granted an option to purchase 6,286 shares of Common Stock at a purchase price of $14.96 per share pursuant to the Issuer’s 2015 Stock Option and Incentive Plan (the “2015 Stock Plan”).

On September 25, 2015, the Schimmel Trust gifted 11,925 shares to an individual.

On April 5, 2016, Prototype PSP purchased on the open market 25,000 shares of Common Stock at a weighted average purchase price of $3.527 per share.  

On January 27, 2016, Dr. Schimmel was granted an option to purchase 19,428 shares of Common Stock at a purchase price of $6.14 per share pursuant to the Issuer’s 2015 Stock Plan.

On April 6, 2016, Prototype PSP purchased on the open market 25,000 shares of Common Stock at a $3.20 per share.

On April 7, 2016, Prototype PSP purchased on the open market 40,000 shares of Common Stock at a weighted average purchase price of $3.1896 per share.

On April 8, 2016, Prototype PSP purchased on the open market 85,000 shares of Common Stock at a weighted average purchase price of $3.2194 per share.

On April 11, 2016, Dr. Schimmel purchased 5,259 shares of Common Stock at a weighted average purchase price of $3.5921 per share and Prototype PSP purchased on the open market 22,100 shares of Common Stock at a weighted average purchase price of $3.5913 per share and 5,300 shares of Common Stock at a purchase a weighted average purchase price of $3.4481 per share.

On April 12, 2016, Dr. Schimmel purchased on the open market 2,581 shares of Common Stock at a weighted average purchase price of $3.7521 per share and Prototype PSP purchased on the open market 6,546 shares of Common Stock at a weighted average purchase price of $3.6999 per share.

On April 13, 2016, Prototype PSP purchased on the open market 9,835 shares of Common Stock at a purchase price of $3.85 per share.

On April 14, 2016, Dr. Schimmel purchased on the open market 32,600 shares of Common Stock at a weighted average purchase price of $4.4134 per share and Prototype PSP purchased on the open market 33,619 shares of Common Stock at a weighted average purchase price of $4.2196 per share.

On May 24, 2016, Dr. Schimmel was granted an option to purchase 18,000 shares of Common Stock at a purchase price of $3.33 per share pursuant to the Issuer’s 2015 Stock Plan.

On December 15, 2016, the Schimmel Trust purchased on the open market 40,000 shares of Common Stock at a weighted average purchase price of $2.4978 per share.  

On December 16, 2016, the Schimmel Trust purchased on the open market 10,000 shares of Common Stock at a weighted average purchase price of $2.3973 per share.  

On December 20, 2016, the Schimmel Trust purchased on the open market 15,000 shares of Common Stock at a weighted average purchase price of $2.274 per share.  

On December 21, 2016, the Schimmel Trust purchased on the open market 10,000 shares of Common Stock at a weighted average purchase price of $2.2818 per share.  

On May 9, 2017, Dr. Schimmel was granted an option to purchase 20,000 shares of Common Stock at a purchase price of $3.15 per share pursuant to the Issuer’s 2015 Stock Plan.

On August 31, 2017, Prototype PSP purchased 94,336 shares of Common Stock and warrants to purchase 35,376 shares of Common Stock at a price per unit of $2.65, which was the price per unit paid by other investors in a private placement transaction.

On May 15, 2018, Prototype PSP purchased on the open market 150,000 shares of Common Stock at a weighted average purchase price of $0.9963 per share.  

On May 15, 2018, Dr. Schimmel was granted an option to purchase 20,000 shares of Common Stock at a purchase price of $1.35 per share pursuant to the Issuer’s 2015 Stock Plan.

 On August 29, 2018, Prototype PSP purchased on the open market 75,136 shares of Common Stock at a weighted average purchase price of $0.7199 per share.  

 On August 30, 2018, Prototype PSP purchased on the open market 89,275 shares of Common Stock at a weighted average purchase price of $0.7559 per share.  

 On August 31, 2018, Prototype PSP purchased on the open market 22,000 shares of Common Stock at a weighted average purchase price of $0.716 per share.  

 On September 4, 2018, Prototype PSP purchased on the open market 20,749 shares of Common Stock at a weighted average purchase price of $0.7571 per share.  

The source of the funds for all purchases and acquisitions by Dr. Schimmel and the Schimmel Trust was from personal funds.  The source of the funds for all purchases and acquisitions by Prototype PSP was working capital of Prototype PSP.  No part of the purchase price was borrowed by Reporting Persons for the purpose of acquiring any securities discussed in this Item 3.  

Item 4.  Purpose of Transaction.

The Reporting Persons acquired the shares of Common Stock for investment in the ordinary course of business, as they believed that such shares represented an attractive investment opportunity.   

In connection with the Reporting Persons’ investment in the Issuer, and as may be appropriate from time to time, each of the Reporting Persons may also consider the feasibility and advisability of various alternative courses of action with respect to such investment, including, without limitation: (a) the acquisition or disposition by the Reporting Persons of its shares of Common Stock, including through derivative transactions which may include security-based swaps and short sales; (b) an extraordinary corporate transaction, such as a merger, reorganization or liquidation, involving the Issuer or any of its subsidiaries; (c) a sale or transfer of a material amount of assets of the Issuer or any of its subsidiaries; (d) changes in the present board of directors or management of the Issuer; (e) a material change in the present capitalization or dividend policy of the Issuer; (f) other material changes in the Issuer’s business or corporate structure; (g) changes in the Issuer’s certificate of incorporation or bylaws or other actions that may impede the acquisition of control of the Issuer by any person; (h) causing any class of the Issuer’s securities to be delisted from a national securities exchange or to cease to be authorized to be quoted in an inter-dealer quotation system of a registered national securities association; (i) causing a class of equity securities of the Issuer to become eligible for termination of registration pursuant to Section 12 of the Exchange Act; or (j) any action similar to those enumerated above. The Reporting Persons may communicate with the Board, members of management and/or other stockholders from time to time with respect to operational, strategic, financial or governance matters or otherwise work with management and the Board. Except as described in Item 6 and this Item 4 and any plans or proposals that may from time to time be discussed or considered by the directors of the Issuer, including Dr. Schimmel, in his fiduciary capacity as a director of the Issuer, the Reporting Persons do not currently have any plans or proposals that relate to or would result in any of the actions specified in clause (a) through (j) of this paragraph.

The Reporting Persons reserve the right, based on all relevant factors and subject to applicable law or other restrictions, at any time and from time to time, to acquire additional securities of the Issuer, dispose of some or all of the shares of Common Stock or such other securities, in each case in open market or private transactions, block sales or otherwise, and review or reconsider their position, change their purpose, take other actions (including actions that could involve one or more of the types of transactions or have one or more of the results described in clauses (a) through (j) of the foregoing paragraph of this Item 4) or formulate and implement plans or proposals with respect to any of the foregoing.

Item 5.  Interest in Securities of the Issuer.

Item 6.  Contracts, Arrangements, Understandings or Relationships with Respect to Securities of the Issuer.

The Reporting Persons are party to a Registration Rights and Voting Agreement among the Issuer, the Reporting Persons and other stockholders.  Subject to the terms of such Registration and Voting Rights Agreement, holders of Common Stock having registratio n rights can demand that Issuer file a registration statement or request that their shares be covered by a registration statement that the Issuer is otherwise filing.  Such Registration and Voting Rights Agreement dated as of March 31, 2015 described in th is Item 6, was filed on April 27, 2015 as Exhibit 10.11 to Amendment No. 1 to the Issuer’s Registration Statement on Form S-1 (File No. 333-203272), and is incorporated herein by reference.  

Prototype PSP holds warrants to purchase 33,376 shares of Common Stock.  The form of warrant was filed on August 28, 2017 as an Exhibit to the Issuer’s Form 8-K (File No. 001-37378), and is incorporated herein by reference.

Dr. Schimmel holds options to purchase shares of Common Stock under the Company’s 2014 Stock Plan and 2015 Stock Plan, (collectively, the “Stock Plans”).  The Stock Plans and forms of agreements thereunder were filed on April 27, 2015 as Exhibits 10.1 and 10.2 to Amendment No. 1 to the Issuer’s Registration Statement on Form S-1 (File No. 333-203272), and are incorporated herein by reference.

Item 7.  Material to Be Filed as Exhibits.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.