FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Quirk Brian Charles
2. Issuer Name and Ticker or Trading Symbol

MKS INSTRUMENTS INC [ MKSI ]
5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
Sr. VP, Global Operations
(Last)          (First)          (Middle)

2 TECH DRIVE, SUITE 201
3. Date of Earliest Transaction (MM/DD/YYYY)

2/15/2018
(Street)

ANDOVER, MA 01810
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   2/15/2018     M    2181.553   A   (1) 14044.436   D    
Common Stock   2/15/2018     M    1773.149   A   (1) 15817.585   D    
Common Stock   2/15/2018     M    2805   A   (1) 18622.585   D    
Common Stock   2/15/2018     M    2157   A   (1) 20779.585   D    
Common Stock   2/15/2018     M    1489   A   (1) 22268.585   D    
Common Stock   2/15/2018     M    1230   A   (1) 23498.585   D    
Common Stock   2/15/2018     F (2)    3858   D $111.10   19640.585   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Restricted Stock Unit     (1) 2/15/2018     A      3375.338         (3)   (3) Common Stock   3375.338     (1) 9159.186   D    
Restricted Stock Unit     (1) 2/15/2018     A      2250.225         (4)   (4) Common Stock   2250.225     (1) 6870.992   D    
Restricted Stock Unit     (1) 2/15/2018     M         2181.553      (5)   (5) Common Stock   2181.553     (1) 10077.848   D    
Restricted Stock Unit     (1) 2/15/2018     M         1773.149      (6)   (6) Common Stock   1773.149     (1) 8007.767   D    
Restricted Stock Unit     (1) 2/15/2018     M         2805      (7)   (7) Common Stock   2805     (1) 7272.848   D    
Restricted Stock Unit     (1) 2/15/2018     M         2157      (8)   (8) Common Stock   2157     (1) 5850.767   D    
Restricted Stock Unit     (1) 2/15/2018     M         1489      (9)   (9) Common Stock   1489     (1) 5783.848   D    
Restricted Stock Unit     (1) 2/15/2018     M         1230      (10)   (10) Common Stock   1230     (1) 4620.767   D    

Explanation of Responses:
(1)  Each restricted stock unit represents the contingent right to receive one share of common stock of MKS Instruments, Inc.
(2)  This transaction was effected pursuant to a Rule 10b5-1 trading plan previously adopted by the reporting person.
(3)  These RSUs are subject to the achievement of performance criteria determined in the first year of grant and thereafter vest in three equal annual installments beginning on February 15, 2019, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.
(4)  These RSUs vest in three equal annual installments commencing on February 15, 2019, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.
(5)  These RSUs are subject to the achievement of performance criteria determined in the first year of grant and thereafter vest in three equal annual installments beginning on February 15, 2016, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.
(6)  These RSUs vest in three equal annual installments commencing on February 15, 2016, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.
(7)  These RSUs are subject to the achievement of performance criteria determined in the first year of grant and thereafter vest in three equal annual installments beginning on February 15, 2017, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.
(8)  These RSUs vest in three equal annual installments commencing on February 15, 2017, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.
(9)  These RSUs are subject to the achievement of performance criteria determined in the first year of grant and thereafter vest in three equal annual installments beginning on February 15, 2018, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.
(10)  These RSUs vest in three equal annual installments commencing on February 15, 2018, provided that if, in any vesting year, February 15th is not a business day, such vesting shall occur on the next business day.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Quirk Brian Charles
2 TECH DRIVE, SUITE 201
ANDOVER, MA 01810


Sr. VP, Global Operations

Signatures
/s/ M. Kathryn Rickards, attorney-in-fact 2/16/2018
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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