Statement of Changes in Beneficial Ownership (4)

FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^* ROSE WILLIAM	2. Issuer Name and Ticker or Trading Symbol REATA PHARMACEUTICALS INC [ RETA ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __ X __ Director __ X __ 10% Owner _____ Officer (give title below) __ X __ Other (specify below) Member of 10% owner group
(Last) (First) (Middle) 3963 MAPLE AVENUE, SUITE 200	3. Date of Earliest Transaction (MM/DD/YYYY) 12/7/2017
(Street) DALLAS, TX 75219 (City) (State) (Zip)	4. If Amendment, Date Original Filed (MM/DD/YYYY)	6. Individual or Joint/Group Filing (Check Applicable Line) ___ Form filed by One Reporting Person _ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	3. Trans. Code (Instr. 8)		4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
1.Title of Security (Instr. 3)	2. Trans. Date	2A. Deemed Execution Date, if any	Code	V	Amount	(A) or (D)	Price		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
Class A Common Stock	12/7/2017		W	V	67735	D	$0.00	0	I	See Footnote ⁽¹⁾

*Table II - Derivative Securities Beneficially Owned ( e.g.* , puts, calls, warrants, options, convertible securities)**
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	4. Trans. Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
1. Title of Derivate Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Trans. Date	3A. Deemed Execution Date, if any	Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	8. Price of Derivative Security (Instr. 5)			11. Nature of Indirect Beneficial Ownership (Instr. 4)
Class B Common Stock	⁽²⁾	12/7/2017		W	V		1877998	⁽²⁾	⁽²⁾	Class A Common Stock	1877998	$0.00	0	I	See Footnote ⁽³⁾

Explanation of Responses:
(1)	These shares were owned directly by the Estate of Edward W. Rose III, a ten percent owner of the issuer, for which Charles E. Gale serves as executor. On 12/7/17, these shares were transferred to the Evelyn Potter Rose Survivor's Trust, for which Charles E. Gale and Evelyn P. Rose serve as co-trustees.
(2)	The Class B common stock is convertible into Class A common stock on a one-for-one basis at the holder's election. The conversion right of the Class B common stock has no expiration date.
(3)	These shares were owned directly by the Estate of Edward W. Rose III, a ten percent owner of the issuer, for which Charles E. Gale serves as the executor. These shares were transferred to the Evelyn Potter Rose Survivor's Trust, for which Charles E. Gale and Evelyn P. Rose serve as co-trustees.

Remarks:
The reporting persons may be deemed to be members of a group with other affiliated entities that collectively are 10% owners, which group includes William E. Rose, Evelyn P. Rose, Evelyn P. Rose SEP IRA, Evelyn Potter Rose Survivor's Trust, Charles Henry Rose 2001 Trust, John William Rose 2002 Trust, Charles E. Gale, Charles E. Gale Fidelity Rollover IRA, Puffin Partners, L.P., Puffin GP, LLC, Montrose Investments I, L.P. and Montrose Investments GP, LLC (collectively, the "Affiliated Rose Reporting Persons"). The reporting persons disclaim the existence of a group and disclaim beneficial ownership of any securities held by the other Affiliated Rose Reporting Persons, except to the extent of their respective pecuniary interests therein.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
ROSE WILLIAM 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219	X	X		Member of 10% owner group
Puffin Partners, L.P. 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of a 10% owner group
Puffin GP, LLC 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of a 10% owner group
Montrose Investments I, L.P. 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of a 10% owner group
Montrose Investments GP, LLC 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219				Member of a 10% owner group
Gale Charles E. 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219		X		Member of a 10% owner group
Estate of Edward W. Rose III 3963 MAPLE AVENUE, SUITE 200 DALLAS, TX 75219		X		Member of a 10% owner group

Signatures
/s/ Charles E. Gale, Attorney-In-Fact for William E. Rose		12/7/2017
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, as Co-Manager of Puffin GP, LLC, the General Partner of Puffin Partners, L.P		12/7/2017
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Co-Manager of Puffin GP, LLC		12/7/2017
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Attorney-In-Fact for Montrose Investments I, L.P.		12/7/2017
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Attorney-In-Fact for Montrose Investments GP, LLC		12/7/2017
^** Signature of Reporting Person		Date
/s/ Charles E. Gale		12/7/2017
^** Signature of Reporting Person		Date
/s/ Charles E. Gale, Executor of Estate of Edward W. Rose III		12/7/2017
^** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
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