Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^*

Sapiro Vadim M.

2. Date of Event Requiring Statement (MM/DD/YYYY) 11/9/2017

3. Issuer Name and Ticker or Trading Symbol

OPGEN INC [OPGEN,OPGN]

(Last) (First) (Middle)

C/O OPGEN, INC. 708 QUINCE ORCHARD ROAD, SUITE 205

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director _____ 10% Owner
___ X ___ Officer (give title below) _____ Other (specify below)
Chief Information Officer /

(Street)

GAITHERSBURG, MD 20878

(City) (State) (Zip)

5. If Amendment, Date Original Filed (MM/DD/YYYY)

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	40115	D

*Table II - Derivative Securities Beneficially Owned ( e.g.* , puts, calls, warrants, options, convertible securities)**
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivate Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security		6. Nature of Indirect Beneficial Ownership (Instr. 5)
Stock Options	3/23/2012	3/23/2022	Common Stock	64	$7.91	D
Stock Options	3/23/2015	3/23/2022	Common Stock	918	$7.91	D
Stock Options	2/12/2017	2/12/2023	Common Stock	253	$7.91	D
Stock Options	2/12/2014	2/12/2023	Common Stock	127	$7.91	D
Stock Options	7/25/2017	2/25/2023	Common Stock	633	$7.91	D
Stock Options	⁽¹⁾	4/24/2024	Common Stock	3589	$0.05	D
Stock Options	⁽²⁾	10/23/2024	Common Stock	50000	$0.61	D
Stock Options	5/4/2016	5/4/2025	Common Stock	25000	$6.00	D
Stock Options	⁽²⁾	6/13/2026	Common Stock	40000	$1.55	D
Stock Options	⁽³⁾	2/23/2027	Common Stock	55000	$1.03	D
Stock Options	8/9/2018	8/9/2027	Common Stock	60000	$0.295	D
Warrants	5/19/2016	5/19/2021	Common Stock	9837	$1.31	D
Warrants	7/18/2017	7/18/2022	Common Stock	25000	$0.425	D
Restricted Stock Units	⁽⁴⁾	⁽⁴⁾	Common Stock	35000	$0.00	D

Explanation of Responses:
(1)	Vests 25% on December 31, 2014 and 6.25% quarterly thereafter in equal proportions over a three-year period.
(2)	Vests 25% on first anniversary of the Date of Grant and 6.25% at the end of each quarterly period thereafter starting with the first full calendar quarter, in equal proportions, over a three-year period with the full remaining amount vesting four years from the Date of Grant.
(3)	Vests 25% on first anniversary of the Date of Grant and 6.25% quarterly thereafter on the first business day of each quarter for a period of three years.
(4)	The restricted stock units vest upon the successful launch of OpGen, Inc's cUTI RUO mAST.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
Sapiro Vadim M. C/O OPGEN, INC. 708 QUINCE ORCHARD ROAD SUITE 205 GAITHERSBURG, MD 20878			Chief Information Officer

Signatures
/s/ Vadim M. Sapiro		11/17/2017
^** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.