APTO Aptose Biosciences Inc

      CUSIP No.                   03835T200

          1.Names of Reporting Persons.

             Laurence W.Lytton

2. Check the Appropriate Box if a Member of a Group (See Instructions)

a)..........................................................................

(b)..........................................................................

      3.SEC Use Only

      4.Citizenship or Place of Organization

                USA

      5.Sole Voting Power        1,193,481

      6.Shared Voting Power       0

      7.Sole Dispositive Power    1,193,481

      8.Shared Dispositive Power    0


      9.Aggregate Amount Beneficially Owned by Each Reporting
      Person
                        1,193,481

      10.Check if the Aggregate Amount in Row (9) Excludes Certain Shares
(See Instructions).................................


      11.Percent of Class Represented by Amount in Row (9)

                  5.5%  (1)

     (1) Based on 21,753,851 common shares issued and outstanding as of
         May 11, 2017 as reported in the May 12, 2107 6-K.

      12.Type of Reporting Person (See Instructions)

                        IN

            Item 1.

      (a)Name of Issuer         APTOSE BIOSCIENCES INC.


      (b)Address of Issuer's Principal Executive Offices

                        5955 Airport Road, Suite #228
                        Mississauga, Ontario
                        L4V 1R9 Canada


              Item 2.

      (a)Name of Person Filing  Laurence W. Lytton

      (b)Address of Principal Business Office or, if none, Residence

                467 CPW
                N.Y., NY  10025

      (c)Citizenship                    USA

      (d)Title of Class of Securities   Common

      (e)CUSIP Number                    03835T200


      Item 3.   not applicable


      Item 4.Ownership.

      (a)Amount beneficially owned:      1,193,481 consisting of
        1,169,172 shares held by the reporting person and 24,309 held in
        the AWL Family LLC.

      (b)Percent of class:   5.5%

      (c)Number of shares as to which the person has:

      (i)Sole power to vote or to direct the vote       1,193,481

      (ii)Shared power to vote or to direct the vote

      (iii)Sole power to dispose or to direct the disposition of    1,193,481

      (iv)Shared power to dispose or to direct the disposition of


      Item 5.Ownership of Five Percent or Less of a Class:
        If this statement is being filed to report the fact that as of the
        date hereof the reporting person has ceased to be the beneficial
        owner of more than 5 percent of the class of securities, check the
        following ( ).


      Item 6.Ownership of More than Five Percent on Behalf of Another Person.

                        Not applicable

      Item 7.Identification and Classification of the Subsidiary Which
Acquired the Security Being Reported on By the Parent Holding Company

                        Not applicable

      Item 8.Identification and Classification of Members of the Group

                        Not applicable

      Item 9.Notice of Dissolution of Group

                        Not applicable

      Item 10.Certification

      By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were not acquired and are not held
for the purpose of or with the effect of changing or influencing the control
of the issuer of the securities and were not acquired and are not held
in connection with or as a participant in any transaction having that
purpose or effect.


SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete
and correct.
      ___6/8/17____________________________
      Date
      ____s/ Laurence W. Lytton____________________________
      Signature
      _____Laurence W. Lytton___________________________
      Name/Title