UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

NOTICE OF EFFECTIVENESS

Effective Date: September 16, 2019
Form: S-1
CIK: 0001417926
Company Name: INVO Bioscience, Inc.
File Number: 333-228928
INVO BioScience (QB) (USOTC:IVOB)
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