Amgen: Phase 3 Study of Kyprolis, Darzalex Meets Primary Endpoint

Date : 09/13/2019 @ 2:51PM
Source : Dow Jones News
Stock : Johnson and Johnson (JNJ)
Quote : 132.84  0.0 (0.00%) @ 2:03PM

Amgen: Phase 3 Study of Kyprolis, Darzalex Meets Primary Endpoint

Amgen (NASDAQ:AMGN)
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By Colin Kellaher

 

Amgen Inc. (AMGN) on Friday said a phase 3 study evaluating its cancer drug Kyprolis in combination with dexamethasone and Johnson & Johnson's (JNJ) Darzalex compared with Kyprolis and dexamethasone alone met its primary endpoint of progression-free survival.

The Thousand Oaks, Calif., biotechnology company said the regimen resulted in a 37% reduction in the risk of progression or death in patients with relapsed or refractory multiple myeloma, a cancer that forms in a type of white blood cells called plasma cells and causes cancer cells to accumulate in the bone marrow.

Amgen said the phase 3 study confirms the benefit for patients shown in an earlier phase 1 study using the same combination, adding that it plans to discuss the data with health authorities in preparation for regulatory submissions.

 

Write to Colin Kellaher at colin.kellaher@wsj.com

 

(END) Dow Jones Newswires

September 13, 2019 09:36 ET (13:36 GMT)

Copyright (c) 2019 Dow Jones & Company, Inc.

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