Eli Lilly Says Taltz Met Endpoints in Axial Spondyloarthritis Study

Date : 11/12/2019 @ 1:28PM
Source : Dow Jones News
Stock : Eli Lilly and Co (LLY)
Quote : 119.77  0.0 (0.00%) @ 8:59AM

Eli Lilly Says Taltz Met Endpoints in Axial Spondyloarthritis Study

Eli Lilly (NYSE:LLY)
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By Michael Dabaie

 

Eli Lilly and Co. (LLY) said Taltz met the primary and all major secondary endpoints in the COAST-X placebo-controlled Phase 3 study in non-radiographic axial spondyloarthritis.

In the study, Taltz improved the signs and symptoms of non-radiographic axSpA as measured by ASAS40, as well as reduced inflammation on MRI, the company said.

Axial spondyloarthritis is a chronic inflammatory disease affecting predominantly the sacroiliac joints and the spine skeleton and is estimated to affect 4.5 million adults worldwide.

A total of 303 adult patients with active nr-axSpA were randomized to receive Taltz 80 mg subcutaneously every four weeks or every two weeks, or placebo. At week 16, 35% of patients treated every four weeks and 40% of patients treated every two weeks achieved ASAS40 response, compared with 19% with placebo. At week 52, 30% treated every four weeks and 31% treated every two weeks achieved ASAS40 response, compared with 13% with placebo.

 

Write to Michael Dabaie at michael.dabaie@wsj.com

 

(END) Dow Jones Newswires

November 12, 2019 08:13 ET (13:13 GMT)

Copyright (c) 2019 Dow Jones & Company, Inc.

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