FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

COMPTON JENNIFER BRYNN 		2. Issuer Name and Ticker or Trading Symbol

SIMMONS FIRST NATIONAL CORP [ SFNC ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      _____ 10% Owner
__ X __ Officer (give title below)      _____ Other (specify below)
EVP
(Last)          (First)          (Middle)

C/O SIMMONS FIRST NATIONAL CORP., 501 MAIN STREET 		3. Date of Earliest Transaction (MM/DD/YYYY)

2/26/2019
(Street)

PINE BLUFF, AR 71601
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
SFNC                  19553   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Restricted Stock Unit     (1) 2/26/2019     A      3170         (2)   (2) Common   3170   $0   3170   D    
Performance Stock Unit     (3) 2/26/2019     A      6340         (4)   (4) Common   6340   $0   6340   D    

Explanation of Responses:
(1)  Each Restricted Stock Unit represents a contingent right to receive one share of Simmons First National Corporation common stock.
(2)  1,056 Restricted Stock Units vest on February 26, 2020; 1,057 Restricted Stock Units vest on February 26, 2021 and 1,057 Restricted Stock Units vest on February 26, 2022. SFNC shares will be delivered within 30 days of vesting. Events such as retirement, death, disability and other specified events in the agreement may result in earlier vesting.
(3)  Each Performance Stock Unit represents a contingent right to receive one share of Simmons First National Corporation common stock.
(4)  The shares listed are the maximum number of shares which may vest under this grant. Vesting will occur subsequent to the attainment of performance goals set and verified by the Compensation Committee of the Company's Board of Directors for the performance period ending December 31, 2021, contingent upon the reporting person's continued employment with the registrant.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
COMPTON JENNIFER BRYNN
C/O SIMMONS FIRST NATIONAL CORP.
501 MAIN STREET
PINE BLUFF, AR 71601

EVP

Signatures
/s/ Jennifer Brynn Compton by Natalie Gassiott 2/28/2019
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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