FORM 4 [ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      
1. Name and Address of Reporting Person * THOMPSON JAMES H 2. Issuer Name and Ticker or Trading Symbol QUALCOMM INC/DE [ QCOM ] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable)_____ Director                    _____ 10% Owner
__X__ Officer (give title below)    _____ Other (specify below)
Chief Technology Officer
(Last)         (First)         (Middle)
5775 MOREHOUSE DR.
3. Date of Earliest Transaction (MM/DD/YYYY)
10/1/2021
(Street)
SAN DIEGO, CA 92121-1714
(City)       (State)       (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)
 
6. Individual or Joint/Group Filing (Check Applicable Line) _X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock  10/1/2021    M    15686  A $0.0  153119 (1) D   
Common Stock  10/1/2021    M    18949  A $0.0  172068  D   
Common Stock  10/1/2021    M    11065  A $0.0  183133  D   
Common Stock  10/1/2021    F    6006  D $128.71  177127  D   
Common Stock  10/1/2021    F    6243  D $128.71  170884  D   
Common Stock  10/1/2021    F    8950  D $128.71  161934  D   
Common Stock                 4539  I  Childrens' Trust (2)
Common Stock                 45453  I  by Spouse's Trust (3)
Common Stock                 45453  I  by Trust (3)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Restricted Stock Unit   (4) 10/1/2021    M        15686.6301    (5) 10/1/2021 (5) Common Stock  15686.6301  $0.0  0  D   
Restricted Stock Unit   (4) 10/1/2021    M        18949.3421    (6) 10/1/2022 (6) Common Stock  18949.3421  $0.0  18949.3421  D   
Restricted Stock Unit   (4) 10/1/2021    M        11065.7681    (7) 10/1/2023 (7) Common Stock  11065.7681  $0.0  22131.5362  D   

Explanation of Responses:
(1)  Includes 114 and 77 shares acquired under the Company's Employee Stock Purchase Plan on January 31, 2021 and July 31, 2021, respectively.
(2)  Shares are held in individual trusts for the benefit of Dr. Thompson's children. Dr. Thompson disclaims all beneficial ownership for the shares held in trusts for the benefit of his children.
(3)  Securities held by Premier Trust, as trustee.
(4)  Each Restricted Stock Unit is the economic equivalent of one share of Qualcomm common stock and is converted into common stock upon vesting.
(5)  The Restricted Stock Units (and allocable dividend equivalents) vested in equal one-third amounts on October 1, 2019, 2020 and 2021.
(6)  These Restricted Stock Units (and allocable dividend equivalents) vest in equal one-third amounts on October 1, 2020, 2021 and 2022.
(7)  These Restricted Stock Units (and allocable dividend equivalents) vest in equal one-third amounts on October 1, 2021, 2022 and 2023.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
THOMPSON JAMES H
5775 MOREHOUSE DR.
SAN DIEGO, CA 92121-1714


Chief Technology Officer

Signatures
By: David Zuckerman, Attorney-in-Fact For: James H. Thompson 10/4/2021
**Signature of Reporting Person Date
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