Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^*

Zaccarin Denis

2. Date of Event Requiring Statement (MM/DD/YYYY) 4/1/2020

3. Issuer Name and Ticker or Trading Symbol

PACIFIC BIOSCIENCES OF CALIFORNIA, INC. [PACB]

(Last) (First) (Middle)

PACIFIC BIOSCIENCES OF CALIFORNIA, INC., 1305 O'BRIEN DRIVE

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director _____ 10% Owner
___X___ Officer (give title below) _____ Other (specify below)
SVP, Research & Development /

(Street)

MENLO PARK, CA 94025

(City) (State) (Zip)

5. If Amendment, Date Original Filed(MM/DD/YYYY)

6. Individual or Joint/Group Filing(Check Applicable Line)

_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	81281 ⁽¹⁾	D

*Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)*
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivate Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security		6. Nature of Indirect Beneficial Ownership (Instr. 5)
Stock Option (right to buy)	⁽²⁾	7/29/2020	Common Stock	5001	$12.74	D
Stock Option (right to buy)	⁽²⁾	6/15/2021	Common Stock	5000	$11.64	D
Stock Option (right to buy)	⁽²⁾	2/15/2022	Common Stock	28000	$4.79	D
Stock Option (right to buy)	⁽²⁾	2/15/2023	Common Stock	20000	$2.18	D
Stock Option (right to buy)	⁽²⁾	2/18/2024	Common Stock	50000	$7.05	D
Stock Option (right to buy)	⁽²⁾	2/17/2025	Common Stock	50000	$6.91	D
Stock Option (right to buy)	⁽²⁾	2/16/2026	Common Stock	60000	$8.90	D
Stock Option (right to buy)	3/15/2017 ⁽³⁾	2/15/2027	Common Stock	65000	$5.27	D
Stock Option (right to buy)	3/15/2018 ⁽³⁾	2/15/2028	Common Stock	45000	$2.54	D

Explanation of Responses:
(1)	Includes 65,000 shares represented by restricted stock units ("RSUs"). Each RSU represents the Reporting Person's right to receive one share of Common Stock of the Issuer subject to the applicable vesting schedule, provided that the Reporting Person is a service provider through each vesting date.
(2)	The shares subject to the option are fully vested and exercisable.
(3)	One forty-eighth (1/48) of the shares subject to the option vests monthly over a four year period, provided that the Reporting Person is a service provider through each vesting date.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
Zaccarin Denis PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 1305 O'BRIEN DRIVE MENLO PARK, CA 94025			SVP, Research & Development