FORM 4
[ ] Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).         
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES
                                                                                  
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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Index Venture Associates III Ltd 		2. Issuer Name and Ticker or Trading Symbol

Minerva Neurosciences, Inc. [ NERV ] 		5. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                      __ X __ 10% Owner
_____ Officer (give title below)      _____ Other (specify below)
(Last)          (First)          (Middle)

C/O EFG WEALTH SOLUTIONS (JERSEY) LTD., 5TH FLOOR, 44 ESPLANADE 		3. Date of Earliest Transaction (MM/DD/YYYY)

5/17/2019
(Street)

ST. HELIER, Y9 JE1 3FG
(City)        (State)        (Zip)
4. If Amendment, Date Original Filed (MM/DD/YYYY)

 
6. Individual or Joint/Group Filing (Check Applicable Line)

___ Form filed by One Reporting Person
_ X _ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3) 		2. Trans. Date 2A. Deemed Execution Date, if any 3. Trans. Code
(Instr. 8) 		4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4) 		6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock   5/17/2019     S    22718   (1) D $6.0164   (2) 4451643   (3) I   See Footnote   (4)
Common Stock   5/20/2019     S    200   (5) D $6.075   4451443   (6) I   See Footnote   (4)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 3) 		2. Conversion or Exercise Price of Derivative Security 3. Trans. Date 3A. Deemed Execution Date, if any 4. Trans. Code
(Instr. 8) 		5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5) 		6. Date Exercisable and Expiration Date 7. Title and Amount of Securities Underlying Derivative Security
(Instr. 3 and 4) 		8. Price of Derivative Security
(Instr. 5) 		9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
(1)  Represents 3,938 shares sold by Index Ventures III (Jersey), L.P. ("Index III Jersey"), 7,999 shares sold by Index Ventures III (Delaware), L.P. ("Index III Delaware"), 143 shares sold by Index Ventures III Parallel Entrepreneur Fund (Jersey) L.P. ("Index III Parallel" and, together with Index III Jersey and Index III Delaware, the "Index III Funds"), 5,470 shares sold by Index Ventures IV (Jersey) L.P. ("Index IV Jersey"), 519 shares sold by Index Ventures IV Parallel Entrepreneur Fund (Jersey) L.P. ("Index IV Parallel" and, together with Index IV Jersey, the "Index IV Funds"), 4,326 shares sold by Index Ventures V (Jersey), L.P. ("Index V Jersey"), 35 shares sold by Index Ventures V Parallel Entrepreneur Fund (Jersey), L.P. ("Index V Parallel" and, together with Index V Jersey, the "Index V Funds") and 288 shares sold by Yucca (Jersey) SLP ("Yucca Jersey").
(2)  The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.00 to $6.25. The reporting persons undertake to provide to the issuer, any security holder of the issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
(3)  Represents 771,621 shares held directly by Index III Jersey, 1,567,468 shares held directly by Index III Delaware, 27,923 shares held directly by Index III Parallel, 1,071,865 shares held directly by Index IV Jersey, 101,741 shares held directly by Index IV Parallel, 847,641 shares held directly by Index V Jersey, 6,868 shares held directly by Index V Parallel and 56,516 shares held directly by Yucca Jersey.
(4)  Index Venture Associates III Ltd. ("Index III GP") is the general partner of the Index III Funds, Index Venture Associates IV Ltd. ("Index IV GP") is the general partner of the Index IV Funds and Index Venture Associates V Ltd. ("Index V GP") is the general partner of the Index V Funds. Yucca (Jersey) SLP is the Administrator of the Index Co-Investment Scheme acting through Intertrust Employee Benefit Services Limited. Each of Index III GP, Index IV GP and Index V GP disclaims Section 16 beneficial ownership of the securities held by the Index III Funds, Index IV Funds and Index V Funds, respectively, and the shares held by Yucca Jersey, except to the extent of its respective pecuniary interest therein, if any, and this report shall not be deemed an admission that Index III GP, Index IV GP or Index V GP is the beneficial owner of such securities for Section 16 or any other purpose.
(5)  Represents 35 shares sold by Index III Jersey, 70 shares sold by Index III Delaware, 1 share sold by Index III Parallel, 48 shares sold by Index IV Jersey, 5 shares sold by Index IV Parallel, 38 shares sold by Index V Jersey, 0 shares sold by Index V Parallel and 3 shares sold by Yucca Jersey.
(6)  Represents 771,586 shares held directly by Index III Jersey, 1,567,398 shares held directly by Index III Delaware, 27,922 shares held directly by Index III Parallel, 1,071,817 shares held directly by Index IV Jersey, 101,736 shares held directly by Index IV Parallel, 847,603 shares held directly by Index V Jersey, 6,868 shares held directly by Index V Parallel and 56,513 shares held directly by Yucca Jersey.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Index Venture Associates III Ltd
C/O EFG WEALTH SOLUTIONS (JERSEY) LTD.
5TH FLOOR, 44 ESPLANADE
ST. HELIER, Y9 JE1 3FG
X

Index Venture Associates IV Ltd
C/O INTERTRUST FUND SERVICES (JERSEY)
LIMITED, 44 ESPLANADE
ST. HELIER, Y9 JE4 9WG
X

Index Venture Associates V Ltd
C/O INTERTRUST FUND SERVICES (JERSEY)
LIMITED, 44 ESPLANADE
ST. HELIER, Y9 JE4 9WG
X

Yucca (Jersey) SLP
C/O INTERTRUST EMPLOYEE BENEFIT SERVICES
LTD., 44 ESPLANADE
ST. HELIER, Y9 JE4 9WG
X


Signatures
Index Venture Associates III Ltd., By: /s/ Nigel Greenwood, Director 5/21/2019
** Signature of Reporting Person Date

Index Venture Associates IV Ltd., By: /s/ Michael Johnson, Director 5/21/2019
** Signature of Reporting Person Date

Index Venture Associates V Ltd., By: /s/ Michael Johnson, Director 5/21/2019
** Signature of Reporting Person Date

YUCCA (JERSEY) SLP, By Intertrust Employee Benefit Services Limited, as authorized signatory of Yucca (Jersey) SLP in its capacity as Administrator of the Index Co-Investment Scheme, By: /s/ Sarah Earles, /s/ Michael Johnson, Its: Authorized Signatories 5/21/2019
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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