VectorVision®, a wholly-owned subsidiary of Guardion Health Sciences, Inc. (“Guardion” or the “Company”) (Nasdaq: GHSI), a specialty health sciences company that develops medical foods and medical devices in the ocular health marketplace and which is developing nutraceuticals it believes will provide medicinal and health benefits to consumers, announced that it has received approval from the Korean Intellectual Property Office in accordance with the Korean Trademark Act to trademark the CSV-2000. The Korean Intellectual Property Office is the national patent and intellectual property office of South Korea. VectorVision’s CSV-2000 is the first and only computer vision testing device that provides for standardized contrast sensitivity testing, along with the full range of visual acuity, color, astigmatism, fixation and other vision tests.

The VectorVision CSV-2000 is also the only device that contains the AcQviz patented technology for automatically calibrating the monitor light source. AcQviz continuously measures the monitor light level and adjusts the level to 85 cd/m2 – the light level recommended for vision testing by the U.S. National Academy of Science Working Group on Vision Standards, the U.S. Food and Drug Administration and the American National Standards Institute. The AcQviz device is housed in the upper left-hand corner of the screen and communicates via specialized software and miniaturized hardware with the luminance control of the monitor. By incorporating the AcQviz standardization technology with the VectorVision contrast sensitivity test, the CSV-2000 brings true next generation technology to ophthalmic examinations.

“We are pleased to announce that we have received approval from the Korean Intellectual Property Office for the VectorVision CSV-2000, the first and only device that provides standardized contrast sensitivity testing along with the full range of visual acuity, color, astigmatism, fixation and other standard vision tests,” said Dr. David Evans, Ph.D., Guardion’s Interim President and Chief Executive Officer, as well as the founder of VectorVision prior to its acquisition by Guardion in 2017. “This approval is another milestone for Guardion as we continue our efforts to establish meaningful legal protection for our proprietary products and technologies, while we are also continuing to focus on increasing market share, both domestically and internationally.”

About Guardion Health Sciences, Inc.

Guardion is a specialty health sciences company (i) that develops medical foods and medical devices in the ocular health marketplace and (ii) that is developing nutraceuticals that the Company believes will provide medicinal and health benefits to consumers. Information and risk factors with respect to Guardion and its business, including its ability to successfully develop and commercialize its proprietary products and technologies, may be obtained in the Company’s filings with the SEC at www.sec.gov.

About VectorVision®

VectorVision® specializes in the standardization of contrast sensitivity, glare sensitivity, low contrast acuity, and ETDRS acuity vision testing. Its patented standardization system provides the practitioner or researcher the ability to delineate very small changes in visual capability, either as compared to the population or from visit to visit. VectorVision’s® patented technology is considered the standard of care for clinical trials. VectorVision® is a wholly owned subsidiary of Guardion.

About NutriGuard™

NutriGuard™ formulates high-quality nutraceuticals which are designed to supplement consumers’ diets. NutriGuard uses industry standards to establish the safety and efficacy of the products it develops and markets, maintains that commitment through prudent manufacturing and quality assurance programs, and only uses manufacturers who comply with FDA current Good Manufacturing Practices (cGMP) requirements. Guardion plans to increase NutriGuard’s existing customer base and build on its product platform by making NutriGuard products available to patients directly and through recommendations by their physicians.

Forward-Looking Statement Disclaimer

With the exception of the historical information contained in this news release, the matters described herein may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Statements preceded by, followed by or that otherwise include the words “believes,” “expects,” “anticipates,” “intends,” “projects,” “estimates,” “plans” and similar expressions or future or conditional verbs such as “will,” “should,” “would,” “may” and “could” are generally forward-looking in nature and not historical facts, although not all forward-looking statements include the foregoing. These statements involve unknown risks and uncertainties that may individually or materially impact the matters discussed herein for a variety of reasons that are outside the control of the Company, including, but not limited to, the Company’s ability to raise sufficient financing to implement its business plan, the impact of the COVID-19 pandemic on the Company’s business, operations and the economy in general, and the Company’s ability to successfully develop and commercialize its proprietary products and technologies. Readers are cautioned not to place undue reliance on these forward- looking statements, as actual results could differ materially from those described in the forward-looking statements contained herein. Readers are urged to read the risk factors set forth in the Company’s filings with the SEC, which are available at the SEC’s website (www.sec.gov). The Company disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Investor Relations Contact:

Porter, LeVay & Rose, Inc.

Michael PorterTelephone: (212) 564-4700 E-mail: mike@plrinvest.com

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