GBT Global Blood Therapeutics Inc

Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

On March 17, 2021, the Board of Directors (the “Board”) of Global Blood Therapeutics, Inc. (the “Company”) appointed Alexis A. Thompson, M.D., M.P.H., to the Board as a Class I director. Dr. Thompson was appointed to a newly created vacancy resulting from an increase in the size of the Board from nine to ten directors. She will serve on the Board’s research and development (R&D) committee.

A board-certified pediatric hematologist, Dr. Thompson is head of the Hematology Section and director of the Comprehensive Thalassemia Program at the Ann and Robert H. Lurie Children’s Hospital of Chicago, where she also serves as the A. Watson and Sarah Armour Endowed Chair for Childhood Cancer and Blood Disorders. In addition, Dr. Thompson is associate director for equity and minority health at the Robert H. Lurie Cancer Center and Northwestern University Feinberg School of Medicine. She has served on national advisory committees for governmental agencies as well as non-profit organizations focused on improving healthcare access, increasing workforce diversity and reducing health disparities. In 2018, Dr. Thompson served as president of the American Society of Hematology (ASH) and continues to serve on ASH’s Sickle Cell Disease Task Force.

Dr. Thompson is an investigator on multicenter clinical trials as well as her own institutional clinical studies in SCD and thalassemia. She has been a leader in multicenter collaborations, such as the National Heart, Lung, and Blood Institute’s Sickle Cell Disease Implementation Consortium, and has received numerous awards recognizing her expertise in teaching and clinical care. Dr. Thompson received her medical degree from Tulane University, earned her master’s in public health degree from University of California, Los Angeles, and completed her postgraduate training at Children’s Hospital Los Angeles and the Children’s Hospital of Philadelphia (CHOP).

Upon Dr. Thompson’s appointment to the Board, and based on the recommendation of the Board’s Compensation Committee, the Board approved the grant to Dr. Thompson of the following equity awards on March 17, 2021: (i) an option to purchase 11,200 shares of the Company’s common stock at a per share exercise price of $44.28, the closing price of the Company’s common stock on the NASDAQ Global Select Market on the grant date, and (ii) an award of restricted stock units covering 7,200 shares of the Company’s common stock. The option will vest in 36 equal monthly installments over a period of three years from March 17, 2021, and the restricted stock units will vest in three equal annual installments over a period of three years from March 17, 2021, both subject to Dr. Thompson’s continued service on the Board. Dr. Thompson will also be eligible to receive annual equity awards as well as cash retainers in accordance with the Company’s Non-Employee Director Compensation Policy, as in effect from time to time, so long as she continues to serve on the Board. A copy of the Non-Employee Director Compensation Policy is filed as Exhibit 10.16 to the Company’s Annual Report on Form 10-K for the annual period ended December 31, 2020, as filed with the SEC on February 24, 2021.

Dr. Thompson is not a party to any transaction with the Company that would require disclosure under Item 404(a) of Regulation S-K, and there are no arrangements or understandings between Dr. Thompson and any other persons pursuant to which Dr. Thompson was selected as a director.