Physicians Wish More Women Understood They Are Not To
Blame
DUBLIN, June 17, 2020 /PRNewswire/ -- Sixty percent (60%)
of women surveyed feel it's their fault they have cellulite and 57%
feel judged for their cellulite,i according to new
Harris Poll survey results released today by Endo Aesthetics LLC,
an affiliate of Endo International plc (NASDAQ: ENDP). Conversely,
92% of physicians surveyed wish more women understood having
cellulite is not their fault. Although celluliteii
is common, many women are unsure about its root causes, lack
knowledge about treatment options and feel a sense of blame and
judgment for having cellulite.
The Harris Poll survey was conducted online among 2,006 U.S.
women and captured feedback from those ages 18-59 who have
cellulite, as well as 302 board certified dermatologists and
plastic surgeons. Harris polled the women and physicians about
their experience with cellulite and current treatment
options.
Of aesthetic physicians surveyed, 93% said most women want to
know how to improve their cellulite. Additionally, one-third of
women surveyed (34%) feel that having information on what does and
does not cause cellulite would make it easier to have conversations
with their physician about this topic.
"It doesn't surprise me that 60% of women surveyed feel it's
their fault they have cellulite," says Lisa
Donofrio, MD, a New Orleans
based board-certified dermatologist, past president and board
member of the American Society for Dermatologic Surgery, and a
fellow of the American Academy of Dermatology. "I've consulted with
patients who are embarrassed and frustrated with having cellulite;
however, I want them to know that they are not alone. In fact, 80%
of women surveyed said they have cellulite and over three-quarters
of them noted they spend time or effort focused on it. It's a very
common issue that can stem from a variety of factors, including but
not limited to hormones, genetics, skin structure and skin
texture."
Cellulite can have a negative impact on how women perceive
themselves. Nearly half of women surveyed (49%) say they are
bothered "a great deal" or "a lot" by their cellulite. Women most
commonly think about their cellulite at certain times, including
when looking in the mirror (65%), at the beach or pool (54%) and
during warmer weather (46%).iii
"The Harris Poll survey results reinforce that many women are
looking for trusted information and resources from their healthcare
professionals," says Robert Catlin,
Vice President of Aesthetic Sales and Marketing at Endo. "We
undertook this survey to understand how women feel about their
cellulite and to help remove the blame and replace it with data and
information."
Additional highlights from the Harris Poll survey
include:iv
- 67% of women surveyed are frustrated that no amount of exercise
seems to get rid of their cellulite;
- 57% of women surveyed have given up on trying to improve their
cellulite because nothing has worked;
- 92% of physicians surveyed wish women better understood the
root causes of cellulite; and
- 77% of women wish their physician would tell them more about
treatment options that target root causes for cellulite.
Scientists continue to explore treatments that target the root
causes of cellulite in minimally invasive
ways.i Currently, surgical and invasive options get
to the bands under the skin's surface that can cause
cellulite.ii The Harris Poll survey showed
many of the women surveyed tried to improve their cellulite using
various methods, including exercise (71%), diet (58%), topical
treatments (36%), massages (25%) and in-office procedures
(12%). By releasing the Harris Poll survey results, Endo
Aesthetics is seeking to clear up the misinformation that exists
around the etiology of cellulite, which may be one of the
reasons 74% of women surveyed said that "no matter what I do, I
will always have cellulite."v
Research Method
This survey was conducted online
within the U.S. by The Harris Poll between January 2, 2020 and January 26, 2020 on behalf of Endo
Pharmaceuticals among two groups: 2,006 women, ages 18-59 who have
cellulite; and 302 licensed U.S. healthcare professionals,
including 151 dermatologists and 151 plastic surgeons.
Patient data were weighted by age, education, race/ethnicity,
region, income, household size, marital status, and employment
status to be representative of the broader population. Propensity
score weighting was also used to adjust for respondents' propensity
to be online. Dermatologist and plastic surgeon data were weighted
by gender, years in practice, and region, and a post-weight was
applied to the total data to reflect the proportions of
dermatologists and plastic surgeons within the U.S. population.
About Cellulite
Cellulite is a localized alteration in
the contour of the skin that has been reported in over 90 percent
of post-pubertal females and affects women of all races and
ethnicities.vi,vii The presence of cellulite is
associated with changes in dermal thickness, and in the fat cells
and connective tissue below the skin. A primary factor in the cause
of the condition is the collagen containing septae which attach the
skin to the underlying fascia layers. The septae tether the skin
which, with additional contributing protrusions of subcutaneous
fat, causes the surface dimpling characteristic of
cellulite.viii,ix These fibrous septae are
oriented differently with varying thickness in females than in
males, which helps our understanding of cellulite as a
gender-related condition.xi Cellulite clinically
presents on the buttocks, thighs, lower abdomen and arms.
It is known that cellulite is different from generalized
obesity. In generalized obesity, adipocytes undergo hypertrophy and
hyperplasia that is not limited to the pelvis, thighs, and
abdomen.x In areas of cellulite, characteristic
large, metabolically stable adipocytes have physiologic and
biochemical properties that differ from adipose tissue located
elsewhere. An anatomical study in 2019 found that women have
increased fat lobule height compared with men, which may also
contribute to the mattress-like appearance seen as a result of the
tension of the fibrous septae.xi Weight gain can
make cellulite more noticeable, but it may be present even in thin
subjects.
About The Harris Poll
The Harris Poll is a global consulting and market research firm
established in 1963 to help support decision making among leaders.
Harris works with clients in three primary areas: crafting
brand strategy, building corporate reputation, and earning organic
media through public relations research. To learn more,
visit www.theharrispoll.com.
About Endo Aesthetics™ LLC
Endo Aesthetics is
embarking on a mission devoted to pushing the boundaries of
aesthetic artistry. Driven by world-class research and development,
Endo Aesthetics is advancing solutions to address unmet needs
beginning with an investigational treatment for cellulite.
Headquartered in Malvern, PA, Endo
Aesthetics is an affiliate of Endo International plc (NASDAQ:
ENDP). Learn more at https://www.endoaesthetics.com.
About Endo International plc
Endo International plc
(NASDAQ: ENDP) is a highly-focused specialty branded and generics
pharmaceutical company delivering quality medicines to patients in
need through excellence in development, manufacturing and
commercialization. Endo has global headquarters in Dublin, Ireland, and U.S. headquarters in
Malvern, PA. Learn more at
www.endo.com.
Forward Looking Statements
This press release may
contain certain forward-looking statements within the meaning of
the Private Securities Litigation Reform Act of 1995 and Canadian
securities legislation, including, but not limited to, the
statements by Dr. Donofrio and Mr. Catlin, and other
statements regarding the purpose and results of the survey.
Statements including words such as "believes," "expects,"
"anticipates," "intends," "estimates," "plan," "will," "may," "look
forward," "intend," "guidance," "future" or similar expressions are
forward-looking statements. Because these statements reflect Endo's
current views, expectations and beliefs concerning future events,
they involve risks and uncertainties. Although Endo believes that
these forward-looking statements and information are based upon
reasonable assumptions and expectations, readers should not place
undue reliance on them, or any other forward-looking statements or
information in this news release. Investors should note that many
factors, as more fully described in the documents filed by Endo
with the Securities and Exchange Commission ("SEC") and with
securities regulators in Canada on
the System for Electronic Document Analysis and Retrieval
("SEDAR"), including under the caption "Risk Factors" in Endo's
Form 10-K, Form 10-Q and Form 8-K filings, and as otherwise
enumerated herein or therein, could affect Endo's future
results and could cause Endo's actual results to differ
materially from those expressed in forward-looking statements
contained in this communication. The forward-looking statements in
this press release are qualified by these risk factors. Endo
assumes no obligation to publicly update any forward-looking
statements, whether as a result of new information, future
developments or otherwise, except as may be required under
applicable securities laws.
References:
i Endo Pharmaceuticals data on file 2020.
Cellulite Survey: Women and HCP Survey Results, The Harris Poll
online survey, 1/2/20 – 1/26/20 of 2,006 U.S. women ages 18-59 who
have cellulite and 302 U.S. licensed physicians aged 18+
ii Zerini I et al. Cellulite treatment: a
comprehensive literature review. J Cosmet Dermatol. 2015 Sep
14(3):224-40
iii Endo Pharmaceuticals data on file 2020.
Cellulite Survey: Women and HCP Survey Results, The Harris Poll
online survey, 1/2/20 – 1/26/20 of 2,006 U.S. women ages 18-59 who
have cellulite and 302 U.S. licensed physicians aged 18+
iv Endo Pharmaceuticals data on file 2020.
Cellulite Survey: Women and HCP Survey Results, The Harris Poll
online survey, 1/2/20 – 1/26/20 of 2,006 U.S. women ages 18-59 who
have cellulite and 302 U.S. licensed physicians aged 18+
v Endo Pharmaceuticals data on file 2020. Cellulite
Survey: Women and HCP Survey Results, The Harris Poll online
survey, 1/2/20 – 1/26/20 of 2,006 U.S. women ages 18-59 who
have cellulite and 302 U.S. licensed physicians aged 18+
vi Hexsel, D., & Mazzuco, R. (2013). Cellulite.
Update in Cosmetic Dermatology, p.2
vii Khan MH et al. Treatment of cellulite: Part I.
Pathophysiology. J Am Acad Dermatol. 2010
Mar;62(3):361-70.
viii Querleux B et al. Anatomy and physiology of
subcutaneous adipose tissue by in vivo MRI and spectroscopy:
Relationship with sex and presence of cellulite, Skin Research
and Technology; 8: 118-124.
ix Querleux B et al. Anatomy and physiology of
subcutaneous adipose tissue by in vivo MRI and spectroscopy:
Relationship with sex and presence of cellulite, Skin Research
and Technology; 8: 118-124.
x Khan MH, Victor F, Rao B, Sadick NS. Treatment of
cellulite: Part I. Pathophysiology. J Am Acad Dermatol
2010;62(3):361-370
xi Rudolph C, Hladik C, Hamade H, Frank K, et al.
Structural gender-dimorphism and the biomechanics of the gluteal
subcutaneous tissue - implications for the pathophysiology of
cellulite. Plast Reconstr Surg 2019; 143: 1077-86.
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SOURCE Endo International plc