FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

EPIQ Capital Group, LLC
2. Date of Event Requiring Statement (MM/DD/YYYY)
5/9/2019 

3. Issuer Name and Ticker or Trading Symbol

Cortexyme, Inc. [CTRX]
(Last)        (First)        (Middle)

ONE LOMBARD STREET, SUITE 200
4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                          _____ 10% Owner
_____ Officer (give title below)        ___X___ Other (specify below)
/ IA/Managing Member 10% owner
(Street)

SAN FRANCISCO, CA 94111      

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed(MM/DD/YYYY)
6/14/2019 

6. Individual or Joint/Group Filing(Check Applicable Line)

___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 4338 I (1)By Mr. Boeding as Trustee of the Erin Dominy 2019 Irrevocable Trust (2)
Common Stock 4338 I (1)By Mr. Boeding as Trustee of the Mitsuo Peterson-Cushing 2019 Irrevocable Trust (2)
Common Stock 4338 I (1)By Mr. Boeding as Trustee for the Spencer Dominy 2019 Irrevocable Trust (2)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date ExercisableExpiration DateTitleAmount or Number of Shares

Explanation of Responses:
(1) The reporting persons are EPIQ Capital Group, LLC ("EPIQ") and Chad Boeding. EPIQ is the investment adviser and managing member of EPQ LLC, CTYM PS ("CTYM") and CTEPQ Partners LLC ("CTEPQ"). Together CTYM and CTEPQ beneficially own +10% of the common stock of the issuer. Mr. Boeding is the Managing Member of EPIQ. EPIQ is filing this Form 3 on behalf of itself and Mr. Boeding jointly, but not as a group, and each reporting person expressly disclaims membership in a group, within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended.
(2) Form 3 filed 6/14/2019 is being amended to include ownership information relating to the three trusts reported herein.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director10% OwnerOfficerOther
EPIQ Capital Group, LLC
ONE LOMBARD STREET, SUITE 200
SAN FRANCISCO, CA 94111



IA/Managing Member 10% owner
Boeding Chad
ONE LOMBARD STREET, SUITE 200
SAN FRANCISCO, CA 94111



Managing Member of Managing Me

Signatures
Chad Boeding11/29/2019
**Signature of Reporting PersonDate

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