Can I access these proxy materials on the Internet? Yes. Commencing on or about April 27,
2021, the proxy materials, including the Notice of Annual Meeting, this proxy statement and our Annual Report, will be made available for viewing, printing, and downloading at www.proxyvote.com. The proxy materials will also be available, on
or around April 27, 2021, at http://www.sec.gov. On our website at www.catalystbiosciences.com in the Investor Relations section, we provide links to our filings with the SEC, including this proxy statement, as a courtesy. All
proxy materials will remain posted on www.proxyvote.com at least until the conclusion of the Annual Meeting. Please note that, while our proxy materials will be made available at certain websites, no other information contained on those
websites is incorporated by reference in or considered to be a part of this proxy statement or our future filings with the SEC.
Why is the Annual
Meeting being held only online? We have been closely monitoring developments with the COVID-19 pandemic and the related recommendations, protocols and restrictions issued by public health authorities
and federal, state, and local governments. In light of these ongoing concerns and in order to support the health and well-being of our stockholders, business partners, employees and board of directors, we will be conducting the Annual Meeting solely
online.
What does it mean if I receive multiple proxy cards? If you receive more than one proxy card, it means that your shares are
registered in more than one name or are registered in different accounts. Please sign and return all proxy cards to ensure that all of your shares are voted.
What happens when two stockholders share the same address? We may satisfy the SEC rules regarding delivery of proxy materials by delivering a
single copy of the Notice of Internet Availability and, if applicable, the proxy materials to an address shared by two or more of our stockholders unless we receive contrary instructions from one or more of the stockholders prior to the mailing
date. This delivery method is known as householding and can result in meaningful cost savings for us. To take advantage of this opportunity, we may deliver only a single copy of the Notice of Internet Availability and, if applicable, the
proxy materials to multiple stockholders who share an address, unless contrary instructions are received prior to the mailing date. Similarly, if you share an address with another stockholder and have received multiple copies of the Notice of
Internet Availability and, if applicable, the proxy materials, you may write us at the address above or call us at (650) 266-8657 to request delivery of a single copy of the Notice of Internet Availability
and, if applicable, the proxy materials in the future. We undertake to deliver promptly upon written or oral request a separate copy of the Notice of Internet Availability and, if applicable, the proxy materials to a stockholder at a shared address
to which a single copy of these documents was delivered. If you hold stock as a record stockholder and prefer to receive separate copies of a proxy statement either now or in the future, please contact us.
Voting Information
Who may vote? You are
entitled to vote if our records show that you held one or more shares of the Companys common stock as of the close of business on April 12, 2021, the Record Date for the Annual Meeting. At that time, there were 31,349,740 shares of common
stock outstanding and entitled to vote, and approximately 64 holders of record. Each share entitles you to one vote at the Annual Meeting.
What is
the difference between holding shares as a stockholder of record and as a beneficial owner? If your shares are registered directly in your name with our transfer agent, American Stock Transfer & Trust Company (the Transfer
Agent), you are considered, with respect to those shares, the stockholder of record. As a stockholder of record, you have the right to vote virtually in person at the Annual Meeting and the Notice of Internet Availability was
sent directly to you by the Transfer Agent. If you are a stockholder of record and you requested to receive printed proxy materials, these proxy materials will be mailed to you directly starting on or about April 27, 2021.
If your shares are held in an account at a brokerage firm, bank, broker-dealer, trust, or other similar organization or other holder of record, you are a
considered a beneficial owner of shares held in street name. If you are a
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