SAN DIEGO, June 17, 2019 /PRNewswire/ -- NuVasive, Inc.
(NASDAQ: NUVA), the leader in spine technology innovation, focused
on transforming spine surgery with minimally disruptive,
procedurally integrated solutions, today announced the commercial
launch of Modulus® TLIF-O, a porous titanium spine implant
engineered for the transforaminal lumbar interbody fusion (TLIF)
procedure. This further expands the application of the Company's
Advanced Materials Science™ (AMS) portfolio to more of its
procedural offerings and the most commonly performed procedure in
the spine industry.
Modulus TLIF-O features porous surface technology that, based on
pre-clinical data, provides a favorable environment for bone
in-growth and bone on-growth, and consistently achieves stronger
osseointegration than solid implants with smooth or rough
surfaces.1-4 The porous and roughened endplate design
promotes new bone on-growth at four weeks and demonstrates the
greatest integration strength by 12 weeks compared to alternative
implant materials.5 Modulus TLIF-O's lattice structure
is optimized for each implant size through NuVasive's proprietary
algorithm that balances strength and radiolucency, while also
mimicking the stiffness of bone.5 This optimized lattice
structure enables enhanced imaging for visualization of spinal
fusion compared to solid titanium interbody implants. Modulus
TLIF-O's lordosis cut in the oblique plane, along with the ability
to insert and rotate or impact the implant using the same
instrumentation, enables surgeons to restore sagittal
alignment of the spine while avoiding introduction of an undesired
coronal misalignment.
"Modulus TLIF-O offers multiple lordotic options allowing even
the most hyperlordotic cages to be delivered through a minimally
invasive surgical approach due to the implant design and customized
instrumentation," said Ronjon Paul,
MD, an orthopedic surgeon at The Spine Center of DuPage Medical
Group in Illinois. "Modulus'
uniquely optimized lattice structure and porous surface technology
pair well with biologic components to aid in the fusion
process."
Adhering to the AMS core principles of surface, structure and
imaging, NuVasive continues to pioneer design and manufacturing
methods that combine the inherent benefits of porosity with the
advantageous material properties of polyetheretherketone (PEEK) and
titanium. This provides surgeons with a portfolio of advanced
material implant options that best fit their patient's needs.
"The Modulus implant location and orientation can clearly be
visualized in the disc space. This is extremely helpful in the OR
to educate my trainees, in the clinic to inform my patients
and staff, and in the database for our research and hospital
outcomes administrators. Modulus is a winning situation for all,"
said Adam S. Kanter, MD,
neurosurgeon at University of
Pittsburgh Medical Center.
Later this summer, the Company plans to launch the Modulus
TLIF-A spine implant. This integrates the Modulus surface
technology with a specific design for anterior implant positioning
for the TLIF procedure.
"Modulus TLIF-O represents our continued commitment to
delivering best-in-class implants that enable our surgeon partners
to overcome common challenges faced in traditional posterior
procedures," said Matt Link,
president of NuVasive. "The proprietary engineering behind Modulus
is advancing the science of spine implant surface technology and
helping improve a patient's fusion rates and overall clinical
outcomes."
About NuVasive
NuVasive, Inc. (NASDAQ:
NUVA) is the leader in spine technology innovation, focused on
transforming spine surgery and beyond with minimally disruptive,
procedurally integrated solutions designed to deliver reproducible
and clinically-proven surgical outcomes. The Company's portfolio
includes access instruments, implantable hardware, biologics,
software systems for surgical planning, navigation and imaging
solutions, magnetically adjustable implant systems for spine and
orthopedics, and intraoperative monitoring service offerings. With
more than $1 billion in revenues,
NuVasive has approximately 2,600 employees and operates in more
than 50 countries serving surgeons, hospitals and patients. For
more information, please visit www.nuvasive.com.
Forward-Looking Statements
NuVasive cautions
you that statements included in this news release that are not a
description of historical facts are forward-looking statements that
involve risks, uncertainties, assumptions and other factors which,
if they do not materialize or prove correct, could cause NuVasive's
results to differ materially from historical results or those
expressed or implied by such forward-looking statements. The
potential risks and uncertainties which contribute to the uncertain
nature of these statements include, among others, risks associated
with acceptance of the Company's surgical products and procedures
by spine surgeons, development and acceptance of new products or
product enhancements, clinical and statistical verification of the
benefits achieved via the use of NuVasive's products (including the
iGA® platform), the Company's ability to effectually manage
inventory as it continues to release new products, its ability to
recruit and retain management and key personnel, and the other
risks and uncertainties described in NuVasive's news releases and
periodic filings with the Securities and Exchange Commission.
NuVasive's public filings with the Securities and Exchange
Commission are available at www.sec.gov. NuVasive assumes no
obligation to update any forward-looking statement to reflect
events or circumstances arising after the date on which it was
made.
1Cheng A, Cohen DJ, Kahn A, et al. Laser sintered
porous Ti-6Al-4V implants stimulate vertical bone growth. Ann
Biomed Eng 2017;45(8):2025-35.
2Guyer RD, Abitbol JJ, Ohnmeiss DD, et al. Evaluating
osseointegration into a deeply porous titanium scaffold: A
biomechanical comparison with PEEK and allograft. Spine
2016;41(19):E1146-50.
3Svehla M, Morberg P, Zicat B, et al. Morphometric and
mechanical evaluation of titanium implant integration: comparison
of five surface structures. J Biomed Mater Res
2000;51(1):15-22.
4Torstrick FB, Safranski DL, Burkus JK, et al. Getting
PEEK to stick to bone: The development of porous PEEK for interbody
devices. Tech Orthop 2017;32(3):9.
5Preclinical data on file. Data may not be
representative of clinical results. TR 9604787
View original content to download
multimedia:http://www.prnewswire.com/news-releases/nuvasive-expands-advanced-materials-science-portfolio-with-launch-of-porous-titanium-spine-implant-for-transforaminal-lumbar-interbody-fusion-300868077.html
SOURCE NuVasive, Inc.