By Colin Kellaher 
 

Eli Lilly & Co. (LLY) on Tuesday said patients in a Phase 2 study of mirikizumab in moderate-to-severe ulcerative colitis achieved significantly greater rates of clinical remission at 12 weeks compared with placebo.

The Indianapolis drug maker said the results mark the first safety and efficacy data for an IL-23p19 monoclonal antibody for the treatment of moderate-to-severe ulcerative colitis, a chronic, inflammatory bowel disease affecting the colon.

Eli Lilly said it will initiate a Phase 3 trial of mirikizumab in moderate-to-severe ulcerative colitis this year. The drug is already in a Phase 3 trial in moderate-to-severe plaque psoriasis.

 

Write to Colin Kellaher at colin.kellaher@wsj.com

 

(END) Dow Jones Newswires

June 05, 2018 10:59 ET (14:59 GMT)

Copyright (c) 2018 Dow Jones & Company, Inc.
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