FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Vogt Frederick G

2. Date of Event Requiring Statement (MM/DD/YYYY)
10/20/2017 

3. Issuer Name and Ticker or Trading Symbol

IOVANCE BIOTHERAPEUTICS, INC. [IOVA]

(Last)        (First)        (Middle)

2120 HEMLOCK RD.

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director                            _____ 10% Owner
___ X ___ Officer (give title below)          _____ Other (specify below)
General Counsel /

(Street)

WEST NORRITON, PA 19403       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy)     (1) 11/13/2026   Common Stock   200000   $7.55   D    
Stock Option (right to buy)     (2) 3/15/2027   Common Stock   12600   $7.45   D    

Explanation of Responses:
(1)  The option vested as to 66,666 shares on September 30, 2017 and the remaining 133,334 shares will vest quarterly over the next two years after September 30, 2017, provided the Reporting Person is still providing services to the Issuer on the respective dates.
(2)  The option vests as to 4,200 shares on February 1, 2018 and the remaining 8,400 shares will vest quarterly over the next two years after February 1, 2018, provided the Reporting Person is still providing services to the Issuer on the respective dates.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Vogt Frederick G
2120 HEMLOCK RD.
WEST NORRITON, PA 19403


General Counsel

Signatures
/s/ Frederick G. Vogt 10/20/2017
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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