FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

RALLIS CHRIS A

2. Date of Event Requiring Statement (MM/DD/YYYY)
9/11/2017 

3. Issuer Name and Ticker or Trading Symbol

FENNEC PHARMACEUTICALS INC. [FENC]

(Last)        (First)        (Middle)

68 TW ALEXANDER DRIVE, PO BOX 13628

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                            _____ 10% Owner
_____ Officer (give title below)          _____ Other (specify below)

(Street)

DURHAM, NC 27709       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4) 		2. Amount of Securities Beneficially Owned
(Instr. 4) 		3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5) 		4. Nature of Indirect Beneficial Ownership
(Instr. 5)

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4) 		2. Date Exercisable and Expiration Date
(MM/DD/YYYY) 		3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4) 		4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5) 		6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy)   11/18/2011   11/18/2019   Common Shares   3333   $1.50   D    
Stock Option (right to buy)   4/4/2012   4/4/2020   Common Shares   8333   $0.60   D    
Stock Option (right to buy)   5/17/2012   5/17/2020   Common Shares   9259   $0.54   D    
Stock Option (right to buy)   8/17/2012   8/17/2019   Common Shares   11111   $0.45   D    
Stock Option (right to buy)   11/20/2012   11/20/2020   Common Shares   4792   $1.05   D    
Stock Option (right to buy)   4/3/2013   4/3/2020   Common Shares   4166   $2.40   D    
Stock Option (right to buy)   5/17/2013   5/17/2020   Common Shares   1700   $2.94   D    
Stock Option (right to buy)   8/6/2013   8/6/2020   Common Shares   5208   $0.96   D    
Stock Option (right to buy)   8/23/2013   8/23/2020   Common Shares   16666   $0.72   D    
Stock Option (right to buy)   1/24/2014   1/24/2021   Common Shares   3144   $1.59   D    
Stock Option (right to buy)   4/25/2014   4/25/2021   Common Shares   4329   $2.31   D    
Stock Option (right to buy)   5/15/2014   5/15/2021   Common Shares   1389   $3.60   D    
Stock Option (right to buy)   8/4/2014   8/4/2021   Common Shares   1792   $2.79   D    
Stock Option (right to buy)   11/7/2014   11/7/2021   Common Shares   1960   $2.55   D    
Stock Option (right to buy)   12/31/2014   12/31/2021   Common Shares   10000   $2.69   D    
Stock Option (right to buy)   3/16/2015   3/16/2022   Common Shares   1992   $2.51   D    
Stock Option (right to buy)   5/11/2015   5/11/2022   Common Shares   2173   $2.30   D    
Stock Option (right to buy)   8/3/2015   8/3/2022   Common Shares   2127   $2.35   D    
Stock Option (right to buy)   11/10/2015   11/10/2022   Common Shares   4062   $1.23   D    
Stock Option (right to buy)   6/9/2016   6/9/2023   Common Shares   4098   $2.44   D    
Stock Option (right to buy)   6/9/2016   6/9/2023   Common Shares   10246   $2.44   D    
Stock Option (right to buy)   6/27/2017   6/27/2024   Common Shares   20000   $5.10   D    

Explanation of Responses:

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
RALLIS CHRIS A
68 TW ALEXANDER DRIVE, PO BOX 13628
DURHAM, NC 27709 		X



Signatures
/s/ Chris A. Rallis 9/20/2017
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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