The Indian rupee firmed against the U.S. dollar in afternoon deals on Tuesday, as regional shares rose following positive global cues and encouraging fourth-quarter earnings results from Reliance Industries.

The benchmark BSE Sensex was up 226 points or 0.76 percent at 29,882 in afternoon trading, while the broader Nifty index was up 69 points or 0.75 percent at 9,287.

The rupee advanced to 64.22 against the greenback, its strongest since April 7. Continuation of the rupee's uptrend may see it challenging resistance around the 63.00 region. The pair ended Monday's trading at 64.52.

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