NEOT Neothetics, Inc. (delisted)

(a) Alta Partners VIII, L.P. (“AP VIII”) has sole voting and dispositive control over 213,017 shares of common stock (“Common Stock”) of Neothetics, Inc. (the “Issuer”), except that Alta Partners Management VIII, LLC (“APM VIII”), the general partner of AP VIII, and Farah Champsi (“Champsi”), Daniel Janney (“Janney”) and Guy Nohra (“Nohra”), managing directors of AP VIII, may be deemed to share dispositive and voting power over such stock. Additional information about AP VIII is set forth in Attachment A hereto.

(b) The percentage set forth in row (11) is based on the 13,828,496 outstanding shares of Common Stock as reported in the Issuer’s 10-Q for the quarter ended September 30, 2016 as filed with the Securities and Exchange Commission on November 10, 2016. The information with respect to the shares of Common Stock beneficially owned by the Reporting Person is provided as of December 31, 2016.

(e) Champsi is a managing director of APM VIII and may be deemed to share voting and dispositive control over the 213,017 shares of Common Stock held by AP VIII.

(g) Janney is a managing director of APM VIII and may be deemed to share voting and dispositive control over the 213,017 shares of Common Stock held by AP VIII.

(i) Nohra is a managing director of APM VIII and may be deemed to share voting and dispositive control over the 213,017 shares of Common Stock held by AP VIII.

The following beneficial ownership information is provided as of December 31, 2016.

Please see Attachment A

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than 5 percent of the class of securities, check the following ý

Not applicable.

Not applicable.

No reporting person is a member of a group as defined in Section 240.13d-1(b)(1)(ii)(J) of the Act.

Not applicable.

Not applicable.

EXHIBITS

A: Joint Filing Statement

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

EXHIBIT A

AGREEMENT OF JOINT FILING

We, the undersigned, hereby express our agreement that the attached Schedule 13G is filed on behalf of us.

Attachment A

Alta Partners VIII, L.P. beneficially owns 213,017 shares of Common Stock and exercises sole voting and dispositive control over such shares, except to the extent set forth below.

Alta Partners Management VIII, LLC is the general partner of Alta Partners VIII, L.P. and may be deemed to share the right to direct the voting and dispositive control over the shares held by such fund. Alta Partners Management VIII, LLC disclaims beneficial ownership of all such shares, except to the extent of its pecuniary interest therein.

Mr. Daniel Janney is a managing director of Alta Partners Management VIII, LLC and may be deemed to share the right to direct the voting and dispositive control over the shares held by such fund. Mr. Janney disclaims beneficial ownership of all such shares, except to the extent of his pecuniary interest therein.

Mr. Guy Nohra is a managing director of Alta Partners Management VIII, LLC and may be deemed to share the right to direct the voting and dispositive control over the shares held by such fund. Mr. Nohra disclaims beneficial ownership of all such shares, except to the extent of his pecuniary interest therein.

Ms. Farah Champsi is a managing director of Alta Partners Management VIII, LLC and may be deemed to share the right to direct the voting and dispositive control over the shares held by such fund. Ms. Champsi disclaims beneficial ownership of all such shares, except to the extent of her pecuniary interest therein.