TBRA Tobira Therapeutics, Inc.

CUSIP No. 88883P101

1.

Name of Reporting Person:
Montreux Equity Partners IV, L.P.

2.

Check the Appropriate Box if a Member of Group (See Instructions):

(a)

x

(b)

o

3.

SEC Use Only:

4.

Citizenship or Place of Organization:
California

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With:

5.

Sole Voting Power:
0

6.

Shared Voting Power :
0

7.

Sole Dispositive Power :
0

8.

Shared Dispositive Power:
0

9.

Aggregate Amount Beneficially Owned by Each Reporting Person:
0

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares: o

11.

Percent of Class Represented by Amount in Row (9):
0%

12.

Type of Reporting Person:
PN

CUSIP No. 88883P101

1.

Name of Reporting Person:
Montreux Equity Partners V, L.P.

2.

Check the Appropriate Box if a Member of Group (See Instructions):

(a)

x

(b)

o

3.

SEC Use Only:

4.

Citizenship or Place of Organization:
Delaware

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With:

5.

Sole Voting Power:
0

6.

Shared Voting Power :
0

7.

Sole Dispositive Power :
0

8.

Shared Dispositive Power:
0

9.

Aggregate Amount Beneficially Owned by Each Reporting Person:
0

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares: o

11.

Percent of Class Represented by Amount in Row (9):
0%

12.

Type of Reporting Person:
PN

CUSIP No. 88883P101

1.

Name of Reporting Person:
Montreux IV Associates, L.L.C.

2.

Check the Appropriate Box if a Member of Group (See Instructions):

(a)

x

(b)

o

3.

SEC Use Only:

4.

Citizenship or Place of Organization:
California

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With:

5.

Sole Voting Power:
0

6.

Shared Voting Power :
0

7.

Sole Dispositive Power :
0

8.

Shared Dispositive Power:
0

9.

Aggregate Amount Beneficially Owned by Each Reporting Person:
0

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares: o

11.

Percent of Class Represented by Amount in Row (9):
0%

12.

Type of Reporting Person:
CO

CUSIP No. 88883P101

1.

Name of Reporting Person:
Montreux Equity Management IV, LLC

2.

Check the Appropriate Box if a Member of Group (See Instructions):

(a)

o

(b)

o

3.

SEC Use Only:

4.

Citizenship or Place of Organization:
California

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With:

5.

Sole Voting Power:
0

6.

Shared Voting Power :
0

7.

Sole Dispositive Power :
0

8.

Shared Dispositive Power:
0

9.

Aggregate Amount Beneficially Owned by Each Reporting Person:
0

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares: o

11.

Percent of Class Represented by Amount in Row (9):
0%

12.

Type of Reporting Person:
CO

CUSIP No. 88883P101

1.

Name of Reporting Person:
Montreux Equity Management V, LLC

2.

Check the Appropriate Box if a Member of Group (See Instructions):

(a)

o

(b)

o

3.

SEC Use Only:

4.

Citizenship or Place of Organization:
Delaware

Number of
Shares
Beneficially
Owned by
Each
Reporting
Person With:

5.

Sole Voting Power:
0

6.

Shared Voting Power :
0

7.

Sole Dispositive Power :
0

8.

Shared Dispositive Power:
0

9.

Aggregate Amount Beneficially Owned by Each Reporting Person:
0

10.

Check if the Aggregate Amount in Row (9) Excludes Certain Shares: o

11.

Percent of Class Represented by Amount in Row (9):
0%

12.

Type of Reporting Person:
CO

Item 1.

(a)

Name of Issuer:
Tobira Therapeutics, Inc. (formerly known as Regado Biosciences, Inc.)

(b)

Address of Issuer’s Principal Executive Offices:
701 Gateway Boulevard, Suite 300

South San Francisco, CA 94080

Item 2.

(a)

Name of Person Filing:
Montreux Equity Partners IV, L.P. (“MEP IV”) is a California limited partnership whose principal business is making investments in the securities of other entities. Montreux IV Associates, L.L.C. (“Associates”) is a California limited liability company whose principal business is making investments in the securities of other entities. Montreux Equity Partners V, L.P. (“MEP V”) is a Delaware limited partnership whose principal business is making investments in the securities of other entities. Montreux Equity Management IV, LLC (“MEM IV”) is a California limited liability company, the sole general partner of MEP IV and the manager of Associates. Montreux Equity Management V, LLC (“MEM V”) is a Delaware limited liability company, the sole general partner of MEP V.

(b)

Address or Principal Business Office or, if none, Residence:
One Ferry Building

Suite 255

San Francisco, CA 94111

(c)

Citizenship or Place of Organization:
MEP IV, Associates and MEM IV: California.

MEP V and MEM V: Delaware.

(d)

Title of Class of Securities:
Common Stock

(e)

CUSIP Number:
88883P101

Item 3.

If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

Not applicable.

Item 4.

Ownership:

Provide the following information regarding the aggregate number and percentage of the class of securities of the issuer identified in Item 1.

(a)    Amount Beneficially Owned

(b)    Percent of Class

(c)(i) Number of shares to which the person has sole power to vote or direct the vote

(c)(ii) Number of shares to which the person has shared power to vote or direct the vote

(c)(iii) Number of shares to which the person has sole power to dispose or direct the disposition of

(c)(iv) Number of shares to which the person has shared power to dispose or direct the disposition of

(1)

MEM IV serves as investment manager to and general partner of MEP IV. By reason of such relationships, MEM IV may be deemed to share voting and dispositive power over the Common Stock listed as beneficially owned by MEP IV. Additionally, MEM IV serves as manager of Associates. By reason of this relationship, the MEM IV may also be deemed to share voting and dispositive power over the Common Stock listed as beneficially owned by Associates. MEM IV disclaims beneficial ownership of all of such shares.

(2)

MEM V serves as investment manager to and general partner of MEP V. By reason of such relationships, MEM V may be deemed to share voting and dispositive power over the Common Stock listed as beneficially owned by MEP V. MEM V disclaims beneficial ownership of all of such shares.

Item 5.

Ownership of Five Percent or Less of a Class:

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following x .

Item 6.

Ownership of More than Five Percent on Behalf of Another Person:

Not applicable.

Item 7.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person:

Not applicable.

Item 8.

Identification and Classification of Members of the Group:

Not applicable.

Item 9.

Notice of Dissolution of Group:

Not applicable.

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under §240.14a-11.

MONTREUX EQUITY PARTNERS IV, LP

By:

Montreux Equity Management IV, LLC, its General Partner

By:

/s/ Daniel K. Turner III

Daniel K. Turner III, Managing Member

MONTREUX IV ASSOCIATES, LLC

By:

Montreux Equity Management IV, LLC, its General Partner

By:

/s/ Daniel K. Turner III

Daniel K. Turner III, Managing Member

MONTREUX EQUITY PARTNERS V, LP

By:

Montreux Equity Management V, LLC, its General Partner

By:

/s/ Daniel K. Turner III

Daniel K. Turner III, Managing Member