Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^*

Meyer Christian

2. Date of Event Requiring Statement (MM/DD/YYYY) 1/1/2017

3. Issuer Name and Ticker or Trading Symbol

uniQure N.V. [QURE]

(Last) (First) (Middle)

C/O UNIQURE N.V., MEIBERGDREFF 61

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director _____ 10% Owner
___ X ___ Officer (give title below) _____ Other (specify below)
Chief Medical Officer /

(Street)

AMSTERDAM, P7 1005 BA

(City) (State) (Zip)

5. If Amendment, Date Original Filed (MM/DD/YYYY)

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

*Table II - Derivative Securities Beneficially Owned ( e.g.* , puts, calls, warrants, options, convertible securities)**
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivate Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security		6. Nature of Indirect Beneficial Ownership (Instr. 5)
Performance Share Units	⁽¹⁾	⁽²⁾	Ordinary Shares	12000	$0	D
Stock Option (right to buy)	⁽³⁾	1/28/2026	Ordinary Shares	20000	$18.21	D
Stock Option (right to buy)	⁽⁴⁾	5/27/2024	Ordinary Shares	50000	$9.35	D
Stock Option (right to buy)	⁽⁵⁾	1/9/2023	Ordinary Shares	140652	⁽⁶⁾	D

Explanation of Responses:
( 1)	Performance Share Units of a maximum of 12,000 shares of the Company's Ordinary Shares were granted on January 28, 2016. The Board of Directors shall determine how many Performance Share Units are to be granted in conjunction with a review of certain performance goals associated with the grant. Any such Performance Share Units granted by the Board of Directors shall vest 100% on January 27, 2019.
( 2)	Expiration date is not applicable.
( 3)	The Stock Option vests 25% on January 28, 2017 and 6.25% quarterly thereafter until fully vested.
( 4)	The Stock Option vests 25% on May 27, 2015 and 6.25% quarterly thereafter until fully vested.
( 5)	The Stock Option is fully vested.
( 6)	The Stock Option is exercisable at a price of ?3.07 per share ($3.23, as converted.) The conversion from Euro (?) into U.S. dollars ($) applied the exchange rate as of December 30, 2016 of ?1 to $1.0541.

Remarks:
See Exhibit 24 - Power of Attorney

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
Meyer Christian C/O UNIQURE N.V. MEIBERGDREFF 61 AMSTERDAM, P7 1005 BA			Chief Medical Officer

Signatures
/s/Lauren M. Watson, Attorney-in-Fact		1/6/2017
^** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
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