Initial Statement of Beneficial Ownership (3)

FORM 3	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES	OMB APPROVAL OMB Number: 3235-0104 Estimated average burden hours per response... 0.5
	Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940

1. Name and Address of Reporting Person ^*

Rolke James

2. Date of Event Requiring Statement (MM/DD/YYYY) 1/1/2017

3. Issuer Name and Ticker or Trading Symbol

LA JOLLA PHARMACEUTICAL CO [LJPC]

(Last) (First) (Middle)

C/O LA JOLLA PHARMACEUTICAL COMPANY, 10182 TELESIS COURT, 6TH FLOOR

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

_____ Director _____ 10% Owner
___ X ___ Officer (give title below) _____ Other (specify below)
Chief Scientific Officer /

(Street)

SAN DIEGO, CA 92121

(City) (State) (Zip)

5. If Amendment, Date Original Filed (MM/DD/YYYY)

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)
Common Stock	73328	D

*Table II - Derivative Securities Beneficially Owned ( e.g.* , puts, calls, warrants, options, convertible securities)**
1. Title of Derivate Security (Instr. 4)	2. Date Exercisable and Expiration Date (MM/DD/YYYY)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivate Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security		6. Nature of Indirect Beneficial Ownership (Instr. 5)
Stock Option (Right to Buy)	⁽¹⁾	4/3/2024	Common Stock	21800	$10.83	D
Stock Option (Right to Buy)	⁽²⁾	2/23/2025	Common Stock	23500	$19.69	D
Stock Option (Right to Buy)	⁽³⁾	12/21/2025	Common Stock	34000	$28.24	D

Explanation of Responses:
( 1)	This option represents a right to purchase a total of 21,800 shares of the Issuer's Common Stock one quarter of which shall be fully vested and exercisable on April 3, 2015, with the remaining 16,350 shares vesting quarterly thereafter over the next three years.
( 2)	This option represents a right to purchase a total of 23,500 shares of the Issuer's Common Stock one quarter of which shall be fully vested and exercisable on February 23, 2016, with the remaining 17,625 shares vesting monthly thereafter over the next three years.
( 3)	This option represents a right to purchase a total of 34,000 shares of the Issuer's Common Stock one quarter of which shall be fully vested and exercisable on December 21, 2016, with the remaining 25,500 shares vesting monthly thereafter over the next three years.

Remarks:
Exhibit List: Exhibit 24 - Power of Attorney.

Reporting Owners
Reporting Owner Name / Address	Relationships
Reporting Owner Name / Address	Director	10% Owner	Officer	Other
Rolke James C/O LA JOLLA PHARMACEUTICAL COMPANY 10182 TELESIS COURT, 6TH FLOOR SAN DIEGO, CA 92121			Chief Scientific Officer

Signatures
/s/ Ryan Murr, as attorney-in-fact for James Rolke		1/6/2017
^** Signature of Reporting Person		Date

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note:	File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.