FORM 3
        
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

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Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
                      

1. Name and Address of Reporting Person *

Sisitsky Todd Benjamin

2. Date of Event Requiring Statement (MM/DD/YYYY)
10/3/2016 

3. Issuer Name and Ticker or Trading Symbol

Quintiles IMS Holdings, Inc. [Q]

(Last)        (First)        (Middle)

C/O TPG GLOBAL, LLC, 301 COMMERCE STREET, SUITE 3300

4. Relationship of Reporting Person(s) to Issuer (Check all applicable)

__ X __ Director                            _____ 10% Owner
_____ Officer (give title below)          _____ Other (specify below)

(Street)

FORT WORTH, TX 76102       

(City)              (State)              (Zip)
5. If Amendment, Date Original Filed (MM/DD/YYYY)

 

6. Individual or Joint/Group Filing (Check Applicable Line)

_ X _ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person


Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
No securities beneficially owned   (1) (2) 0   D    

Table II - Derivative Securities Beneficially Owned ( e.g. , puts, calls, warrants, options, convertible securities)
1. Title of Derivate Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(MM/DD/YYYY)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares

Explanation of Responses:
( 1)  Todd Benjamin Sisitsky is a TPG Partner. TPG is affiliated with (i) TPG Partners V, L.P., (ii) TPG FOF V-A, L.P., (iii) TPG FOF V-B, L.P., (iv) TPG Partners VI, L.P., (v) TPG Biotechnology Partners III, L.P., (vi) TPG FOF VI SPV, L.P., (vii) TPG Iceberg Co-Invest LLC, (viii) TPG Quintiles Holdco II, L.P. and (ix) TPG Quintiles Holdco III, L.P. (collectively, the "TPG Funds"), which directly hold 49,651,557 shares of Common Stock of Quintiles IMS Holdings, Inc. (the "Issuer").
( 2)  Mr. Sisitksy disclaims beneficial ownership of all of the securities that are or may be beneficially owned by the TPG Funds or any of their affiliates. Pursuant to Rule 16a-1(a)(4) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), this filing shall not be deemed an admission that Mr. Sisitsky is, for purposes of Section 16 of the Exchange Act or otherwise, the beneficial owner of any equity securities of the Issuer for purposes of Section 16 of the Exchange Act or otherwise.

Remarks:
(3) Michael LaGatta is signing on behalf of Mr. Sisitsky pursuant to the authorization and designation letter dated October 3, 2016, which is attached here as an exhibit.

Reporting Owners
Reporting Owner Name / Address
Relationships
Director 10% Owner Officer Other
Sisitsky Todd Benjamin
C/O TPG GLOBAL, LLC
301 COMMERCE STREET, SUITE 3300
FORT WORTH, TX 76102
X



Signatures
/s/ Michael LaGatta on behalf of Todd Benjamin Sisitsky (3) 10/5/2016
** Signature of Reporting Person Date


Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.
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