LJPC La Jolla Pharmaceutical Company

La Jolla Pharmaceutical Company (NASDAQ: LJPC) (the Company or La Jolla), a leader in the development of innovative therapies intended to significantly improve outcomes in patients suffering from life-threatening diseases, today reported financial results for the three and six months ended June 30, 2016.

Results of Operations

As of June 30, 2016, La Jolla had $100.6 million in cash and cash equivalents, compared to $126.5 million as of December 31, 2015. The decrease in cash and cash equivalents was primarily due to net cash used for operating activities. Based on current operating plans and projections, La Jolla believes that its current cash and cash equivalents are sufficient to fund operations into 2018.

La Jolla’s net cash used for operating activities for the six months ended June 30, 2016 was $25.1 million, compared to net cash used for operating activities of $11.2 million for the same period in 2015. La Jolla’s net loss for the three and six months ended June 30, 2016 was $15.6 million and $32.0 million, or $0.90 per share and $1.86 per share, respectively, compared to a net loss of $10.7 million and $19.6 million, or $0.70 per share and $1.29 per share, respectively, for the same periods in 2015. During the three and six months ended June 30, 2016, La Jolla recognized contract revenue of approximately $0.3 million and $0.5 million, respectively. The net loss includes non-cash, share-based compensation expense of $3.3 million and $7.0 for the three and six months ended June 30, 2016, respectively, compared to $3.9 million and $7.3 million, respectively, for the same periods in 2015.

The increases in net cash used for operating activities and net loss in the 2016 periods as compared to the 2015 periods were primarily due to increased development costs associated with our ATHOS 3 Phase 3 trial of LJPC-501 in patients with catecholamine-resistant hypotension and our Phase 1 trial of LJPC-401 in patients with iron overload. There also were increases in personnel and facility costs associated with the support of these increased development activities.

“The first half of 2016 was a productive period for La Jolla, highlighted by the continued enrollment of our ATHOS 3 Phase 3 trial of LJPC-501 and encouraging interim data from our Phase 1 trial of LJPC-401,” said George Tidmarsh, M.D., Ph.D., La Jolla’s President and Chief Executive Officer. “Catecholamine-resistant hypotension and iron overload remain significant unmet medical needs, and we remain dedicated to bringing our potentially important therapies to patients as expeditiously as possible. We plan to report results from our Phase 1 trial of LJPC-401 in September 2016 and from our ATHOS 3 Phase 3 trial of LJPC-501 in the first quarter of 2017.”

About La Jolla Pharmaceutical Company

La Jolla Pharmaceutical Company is a biopharmaceutical company focused on the discovery, development and commercialization of innovative therapies intended to significantly improve outcomes in patients suffering from life-threatening diseases. The Company has several product candidates in development. LJPC-501 is La Jolla’s proprietary formulation of angiotensin II for the potential treatment of catecholamine-resistant hypotension. LJPC-401 is La Jolla’s novel formulation of hepcidin for the potential treatment of conditions characterized by iron overload, such as hereditary hemochromatosis, beta thalassemia, sickle cell disease and myelodysplastic syndrome. LJPC-30S is our next-generation gentamicin derivative program that is focused on therapeutics for the potential treatment of serious bacterial infections as well as rare genetic disorders, such as cystic fibrosis and Duchenne muscular dystrophy. For more information on La Jolla, please visit www.ljpc.com.

Forward Looking Statement Safe Harbor

This document contains forward-looking statements as that term is defined in the Private Securities Litigation Reform Act of 1995. These statements relate to future events or the Company’s future results of operations. These statements are only predictions and involve known and unknown risks, uncertainties and other factors, which may cause actual results to be materially different from these forward-looking statements. The Company cautions readers not to place undue reliance on any such forward-looking statements, which speak only as of the date they were made. Certain of these risks, uncertainties, and other factors are described in greater detail in the Company’s filings with the U.S. Securities and Exchange Commission (SEC), all of which are available free of charge on the SEC’s web site www.sec.gov. These risks include, but are not limited to, risks relating to: the timing for commencement of clinical studies, the anticipated timing for completion of such studies, and the anticipated timing for regulatory actions; the success of future development activities; potential indications for which the Company’s product candidates may be developed; and the expected duration over which the Company’s cash balances will fund its operations. Subsequent written and oral forward-looking statements attributable to the Company or to persons acting on its behalf are expressly qualified in their entirety by the cautionary statements set forth in the Company's reports filed with the SEC. The Company expressly disclaims any intent to update any forward-looking statements.

    LA JOLLA PHARMACEUTICAL COMPANY   Unaudited Condensed Consolidated Statements of Operations

(in thousands, except per share amounts)

  Three Months Ended June 30, Six Months Ended June 30, 2016   2015 2016   2015 Revenue Contract revenue - related party $ 253   $ —   $ 487   $ —   Total revenue 253   —   487   —   Expenses Research and development 12,404 6,686 25,119 11,856 General and administrative 3,466   3,972   7,519   7,769   Total expenses 15,870   10,658   32,638   19,625   Loss from operations (15,617 ) (10,658 ) (32,151 ) (19,625 ) Other income, net 51   8   104   20   Net loss $ (15,566 ) $ (10,650 ) $ (32,047 ) $ (19,605 ) Basic and diluted net loss per share $ (0.90 ) $ (0.70 ) $ (1.86 ) $ (1.29 ) Shares used in computing basic and diluted net loss per share 17,211   15,251   17,211   15,246       LA JOLLA PHARMACEUTICAL COMPANY   Condensed Consolidated Balance Sheets

(in thousands, except share and par value amounts)

    June 30, 2016 December 31, 2015 (Unaudited) ASSETS Current assets: Cash and cash equivalents $ 100,557 $ 126,467 Restricted cash 200 237 Prepaid clinical expenses 187 223 Prepaid expenses and other current assets 1,356   618   Total current assets 102,300 127,545 Property and equipment, net 2,257 1,732 Other assets 217   70   Total assets $ 104,774   $ 129,347     LIABILITIES AND SHAREHOLDERS’ EQUITY Current liabilities: Accounts payable $ 2,256 $ 2,506 Accrued expenses 2,112 1,224 Accrued payroll and related expenses 795   1,090   Total current liabilities 5,163   4,820   Shareholders’ equity: Common Stock, $0.0001 par value; 100,000,000 shares authorized, 18,254,009 and 18,244,009 shares issued and outstanding at June 30, 2016 and December 31, 2015, respectively 2 2 Series C-12 Convertible Preferred Stock, $0.0001 par value; 11,000 shares authorized, 3,906 shares issued and outstanding at June 30, 2016 and December 31, 2015, and liquidation preference of $3,906 at June 30, 2016 and December 31, 2015 3,906 3,906 Series F Convertible Preferred Stock, $0.0001 par value; 10,000 shares authorized, 2,737 shares issued and outstanding at June 30, 2016 and December 31, 2015, and liquidation preference of $2,737 at June 30, 2016 and December 31, 2015 2,737 2,737 Additional paid-in capital 653,539 646,408 Accumulated deficit (560,573 ) (528,526 ) Total shareholders’ equity 99,611   124,527   Total liabilities and shareholders’ equity $ 104,774   $ 129,347  

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La Jolla Pharmaceutical CompanyGeorge F. Tidmarsh, M.D., Ph.D.President & Chief Executive Officer858-207-4264gtidmarsh@ljpc.comorDennis M. MulroyChief Financial Officer858-433-6839dmulroy@ljpc.com