– Reported Positive Clinical Data from Phase IIb trial of ReJoin® haMPC therapy– Expanded Stem Cell Platform with the Launch of New Allogeneic Clinical Trial– Closed Strategic Investment of $43.13 million in the First Four Months of 2016


Cellular Biomedicine Group, Inc. (Nasdaq:CBMG) ("CBMG" or the "Company"), a clinical-stage biomedicine firm engaged in the development of effective stem cell therapies for degenerative diseases and immunotherapies for cancer, reported financial results for the first quarter ended March 31, 2016 and provided business highlights.

“In the first quarter of 2016, we made several key clinical and business advancements that we expect will promote long-term growth and strengthen our presence in the cancer and osteoarthritis markets,” commented Tony (Bizuo) Liu, CBMG’s Chief Executive Officer.  “We reported encouraging Phase IIb data from our most advanced stem cell program for autologous adipose-derived mesenchymal progenitor cell (haMPC) ReJoin® therapy for Knee Osteoarthritis (KOA), and launched a Phase I clinical trial for an off-the-shelf allogeneic haMPC AlloJoinTM therapy for KOA. The closing of a $43.13 million strategic investment through April 2016 brings us closer to reaching our objectives of launching multi-site clinical trials in immuno-oncology cell therapies in China, to file INDs and launch clinical trials for AlloJoinTM therapy for KOA patients in the US and to further strengthen our pipeline. We are determined to build on the momentum from the first quarter and believe that we can accomplish meaningful progress on our 2016 operating objectives.”

First Quarter 2016 Financial Performance

  1. Cash Position:  Cash and cash equivalents as of March 31, 2016 were $15.7 million compared to $14.9 million as of December 31, 2015. We had an increase in cash generated from financing activities due to a private placement financing in February 2016 for gross proceeds of approximately $5 million.
  2. Net Cash Used in Operating Activities:  Net cash used in operating activities for the first quarter of 2016 was $3.58 million, compared to $2.41 million for the same period in 2015.
  3. Revenue:  Revenues in the first quarter of 2016 were $488,491 compared to $603,390 for the same period in 2015. The revenue in first quarter 2016 is solely comprised of the hospital’s technology services related to cell therapy treatments.
  4. G&A Expenses:  General and administrative expenses for the first quarter of 2016 were $2.8 million compared to $2.7 million for the same period in 2015.
  5. R&D Expenses:  Research and development expenses for the first quarter of 2016 were $2.40 million, compared to $1.46 million for the same period a year ago.  The increase was primarily attributable to the increase of the Company’s immunotherapy research and development team and expenses related to clinical trials.
  6. Net Loss:  Net loss allocable to common stock holders was $4.2 million, compared to $4.3 million for the same period in 2015.  

Business & Technology Highlights of 2016 To Date

  • Announced encouraging 48-week clinical data from the Phase IIb trial of the Company’s ReJoin® haMPC therapy for Knee Osteoarthritis (KOA), revealing increase of patient’s knee cartilage volume and relief of pain;
  • Launched an investigator initiated Phase I clinical trial of an off-the-shelf allogeneic adipose-derived mesenchymal progenitor cell (haMPC) AlloJoinTM therapy for KOA patients in China;
  • Advanced the Company’s cash position following the closing of an agreement with Wuhan Dangdai Science & Technology Industries Group Inc. to invest up to $43.13 million for 2.27 million shares of the Company’s common stock, representing a 16.2% post-money stake investment as of April 15, 2016.

About Cellular Biomedicine Group Cellular Biomedicine Group, Inc. develops proprietary cell therapies for the treatment of certain degenerative and cancerous diseases.  Our developmental stem cell and Immuno-Oncology projects are the result of research and development by scientists and doctors from China and the United States. Our GMP facilities in China, consisting of nine independent cell production lines, are designed, certified and managed according to U.S. standards.  To learn more about CBMG, please visit: www.cellbiomedgroup.com

Forward-Looking Statements Statements in this press release relating to plans, strategies, trends, specific activities or investments, and other statements that are not descriptions of historical facts may be forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking information is inherently subject to risks and uncertainties, and actual results could differ materially from those currently anticipated due to a number of factors, which include risks inherent in doing business, trends affecting the global economy, including the devaluation of the RMB by China in August 2015 and other risks detailed from time to time in CBMG’s reports filed with the Securities and Exchange Commission, quarterly reports on form 10-Q, current reports on form 8-K and annual reports on form 10-K. Forward-looking statements may be identified by terms such as "may," "will," "expects," "plans," "intends," "estimates," "potential," or "continue," or similar terms or the negative of these terms. Although CBMG believes the expectations reflected in the forward-looking statements are reasonable, they cannot guarantee that future results, levels of activity, performance or achievements will be obtained. CBMG does not have any obligation to update these forward-looking statements other than as required by law.

 
CELLULAR BIOMEDICINE GROUP, INC.
CONDENSED CONSOLIDATED STATEMENT OF OPERATIONS AND COMPREHENSIVE LOSS
(UNAUDITED)
         
    For the Three Months Ended
    March 31,
      2016       2015  
         
Net sales and revenue   $  488,491     $  603,390  
         
Operating expenses:        
Cost of sales      503,193        494,062  
General and administrative      2,775,925        2,680,237  
Selling and marketing      178,754        149,022  
Research and development      2,398,362        1,455,420  
Impairment of investments      -         123,428  
Total operating expenses      5,856,234        4,902,169  
Operating loss      (5,367,743 )      (4,298,779 )
         
Other income (expense):        
Interest income      17,050        15,111  
Other income (expense)      16,320        (2,703 )
Total other income      33,370        12,408  
Loss before taxes      (5,334,373 )      (4,286,371 )
         
Income taxes credit (provision)      1,124,260        (800 )
         
         
Net loss   $  (4,210,113 )   $  (4,287,171 )
Other comprehensive income (loss):        
Cumulative translation adjustment      16,073        19,609  
Unrealized gain (loss) on investments, net of tax of $4,514,060 and $nil, for the three months ended March 31, 2016 and 2015, respectively      16,416,517        (2,568,271 )
Total other comprehensive income (loss):      16,432,590        (2,548,662 )
         
Comprehensive gain (loss)   $  12,222,477     $  (6,835,833 )
         
         
Net loss per share :        
Basic   $  (0.35 )   $  (0.39 )
Diluted   $  (0.35 )   $  (0.39 )
         
Weighted average common shares outstanding:        
Basic     11,884,066       11,039,208  
Diluted     11,884,066       11,039,208  
                 
       
CELLULAR BIOMEDICINE GROUP, INC.      
CONDENSED CONSOLIDATED BALANCE SHEETS      
(UNAUDITED)      
         
    March 31,   December 31,
      2016       2015  
         
Assets        
Cash and cash equivalents $  15,667,528     $  14,884,597  
Accounts receivable    582,714        630,332  
Other receivables    316,993        271,344  
Inventory    486,348        390,886  
Prepaid expenses    644,250        367,050  
Taxes recoverable    -         150,082  
Total current assets    17,697,833        16,694,291  
         
Investments    26,309,984        5,379,407  
Property, plant and equipment, net    2,743,466        2,768,900  
Goodwill    7,678,789        7,678,789  
Intangibles, net    15,511,705        15,949,100  
Long-term prepaid expenses and other assets    1,360,679        989,935  
Total assets $  71,302,456     $  49,460,422  
         
Liabilities and Stockholders' Equity      
         
Liabilities:      
Accounts payable $  208,894     $  260,886  
Accrued expenses    902,265        845,087  
Taxes payable    32,450        -   
Other current liabilities    2,026,264        1,913,284  
Total current liabilities    3,169,873        3,019,257  
         
Deferred tax liabilities    3,385,545        -   
Other non-current liabilities    26,311        76,229  
Total liabilities    6,581,729        3,095,486  
         
         
         
Stockholders' equity:      
         
Preferred stock, par value $.001, 50,000,000 shares      
authorized; none issued and outstanding as of      
March 31, 2016 and December 31, 2015, respectively    -         -   
         
Common stock, par value $.001, 300,000,000 shares authorized;      
12,001,188 and 11,711,645 issued and outstanding      
as of March 31, 2016 and December 31, 2015, respectively    12,001        11,711  
Additional paid in capital    109,940,675        103,807,651  
Accumulated deficit    (61,548,424 )      (57,338,311 )
Accumulated other comprehensive income (loss)    16,316,475        (116,115 )
Total stockholders' equity    64,720,727        46,364,936  
         
Total liabilities and stockholders' equity $  71,302,456     $  49,460,422  
               
 
CELLULAR BIOMEDICINE GROUP, INC.
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
         
    For the Three Months Ended
    March 31,
      2016       2015  
     
CASH FLOWS FROM OPERATING ACTIVITIES:        
Net loss   $   (4,210,113 )   $   (4,287,171 )
Adjustments to reconcile net loss to net cash        
used in operating activities:        
Depreciation and amortization       671,649         439,242  
Stock based compensation expense       1,266,063         1,719,458  
Other than temporary impairment on investments       -          123,428  
Realized losses from sale of investments       -          5,178  
Changes in operating assets and liabilities:        
Accounts receivable       50,764         (198,944 )
Other receivables       9,705         (38,463 )
Inventory       (96,083 )       94,381  
Prepaid expenses       (274,829 )       (81,602 )
Taxes recoverable       150,082         -   
Other current assets       -          110,346  
Long-term prepaid expenses and other assets       (38,522 )       (44,340 )
Accounts payable       (51,992 )       (266,744 )
Accrued expenses       57,178         142,276  
Advances  payable to related party       -          (30,216 )
Other current liabilities       29,415         346,585  
Taxes payable       32,450         (226,055 )
Deferred tax liabilities       (1,128,515 )       -   
Other non-current liabilities       (50,049 )       (213,254 )
Net cash used in operating activities       (3,582,797 )       (2,405,895 )
         
CASH FLOWS FROM INVESTING ACTIVITIES:        
Proceed from sale of investments, net of issuance cost paid       -          1,480  
Purchases of intangibles       -          (569,828 )
Purchases of assets       (674,736 )       (179,293 )
Net cash used in investing activities       (674,736 )       (747,641 )
         
CASH FLOWS FROM FINANCING ACTIVITIES:        
Net proceeds from the issuance of common stock       4,970,002         19,564,846  
Proceeds from exercise of stock options       93,249         26,590  
Repayment of advance from affiliate       -          -   
Net cash provided by financing activities       5,063,251         19,591,436  
         
EFFECT OF EXCHANGE RATE CHANGES ON CASH       (22,786 )       (63,817 )
         
INCREASE IN CASH AND CASH EQUIVALENTS       782,932         16,374,083  
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD       14,884,597         14,770,584  
CASH AND CASH EQUIVALENTS, END OF PERIOD   $   15,667,529     $   31,144,667  
         
         
SUPPLEMENTAL CASH FLOW INFORMATION        
         
Cash paid for income taxes   $   (4,255 )   $   (226,855 )
 
Contacts:
Sarah Kelly 
Director of Corporate Communications, CBMG
+1 650 566-5064
sarah.kelly@cellbiomedgroup.com

Vivian Chen
Managing Director Investor Relations, Grayling
+1 347 481-3711
vivian.chen@grayling.com
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