AMSTERDAM—ING Groep NV said Wednesday that its profit rose in the second quarter as the Dutch lender expanded its loan book, booked a gain from an asset sale and reduced its loan-loss provisions.

The Netherlands' largest bank by assets said net profit rose 27% to €1.36 billion ($1.49 billion), lifted by a €376 million gain tied to the sale of its stake in Vysya Bank, an Indian lender. Underlying pretax profit, which strips out divestments and other special items, rose 25% to €1.6 billion.

The results, which were slightly below analysts' expectations, were boosted by continued growth of ING's lending book, which led to an increase in net interest income of 4% to €3.1 billion, while loan-loss provisions dropped 13% to €353 million. This was partly offset by a decline in commission income, which fell 2% to €584 million.

Write to Maarten van Tartwijk at maarten.vantartwijk@wsj.com

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