By Lisa Beilfuss 

Humana Inc. on Monday cut its earnings outlook because of higher-than-expected medical costs as the company discussed its previously announced $34.1 billion tie-up with Aetna Inc.

Humana Chief Executive Bruce Broussard said the company is performing in a "reasonable fashion," but that hospital admissions in its Medicare Advantage business "have not come down as quickly" as it projected.

As a result, the insurer predicted earnings of $1.60 to $1.65 a share for the quarter ended in June, short of the $2.36 anticipated by analysts polled by Thomson Reuters. For the year, Humana sees per-share earnings excluding certain costs of $7.75, down sharply from its previous estimate of $8.50 to $9.

The reduced outlook comes as Humana recently agreed to be bought by rival Aetna for about $230 a share in cash and stock. On a conference call Monday, Aetna Chief Financial Officer Shawn Guertin said Humana's updated outlook was "consistent with the information we examined during our diligence," adding the companies did "months of thoughtful analysis."

Humana also said it had revised its 2016 bids to reflect the higher costs and was confident in its pricing plans. Aetna noted that it had reached the same conclusion after hiring an independent company to review the bids.

According to analysts at Susquehanna International Group, the guidance cut "is not particularly surprising" after Humana in April warned that it saw signs of an uptick in hospital admissions at the end of the first quarter.

Anna Wilde Mathews contributed to this article

Mr. Broussard at the time cited "respiratory issues" and said the admissions may represent "a longer extension of the flu," noting then that the increase appeared to be "an isolated incident."

Still, Humana's lower earnings forecast adds to the concerns surrounding the deal. Analysts have questioned the deal's high price tag, how regulators may react to the deal, and whether Aetna itself may be a takeover target.

Those concerns are contributing to the roughly 13% spread between the deal's offer price and where Humana is trading. In early afternoon trading, Aetna shares had fallen 7.4% to $116.24. Based on the deal's terms, that price would value Humana at about $222.35. Instead, Humana shares were trading at $191.25, up 2% on the day but still more than $30 below the offer price.

Anna Wilde Mathews contributed to this article.

Write to Lisa Beilfuss at lisa.beilfuss@wsj.com

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