Roche Hit by Failure of Cancer Drug Trial 

Roche said a late-stage study of its breast cancer drug Kadcyla failed to yield superior results to an existing treatment, damaging the outlook for stronger sales in one of its key drug markets.

 
Alstom CEO Says Talks With DOJ to Conclude Soon 

Alstom Chief Executive Patrick Kron said that he expects talks with the U.S. Department of Justice will reach a settlement "very soon."

 
BlackBerry's Loss Narrows 

BlackBerry posted a small fiscal 3Q operating profit and achieved positive cash flow earlier than it had targeted. Revenue, however, came in at $793 million, down about 34% from a year ago and coming in below analyst views. Shares down 2% premarket.

 
American Reaches Deal With Flight Attendants 

American Airlines Group said it had reached a joint collective-bargaining deal with the union representing 24,000 flight attendants, clearing up one big area of uncertainty as it continues its integration with US Airways.

 
Atos to Buy Xerox's IT Outsourcing Unit 

Computer-services company Atos will buy Xerox's information technology outsourcing business for $1.05 billion in cash, a deal that would bolster the French company's position in the U.S.

 
BASF, Gazprom Call Off Asset Swap 

Germany's BASF, the world's largest chemical company by revenue, and Russia's OAO Gazprom have called off an asset-swap deal amid mounting political tensions between Russia and the West.