By Anora Mahmudova and Barbara Kollmeyer, MarketWatch

NEW YORK (MarketWatch) -- U.S. stock investors continued their selling ways this week, pushing prices lower in early trading. Wednesday's slide stemmed from upbeat employment and manufacturing data for September, which although points to positive momentum for the U.S. economy, continued to fuel worries that the Federal Reserve may raise interest rates sooner than later.

Private employers added 213,000 new jobs in September and many view the report as a proxy for the non-farm payrolls data due on Friday. Manufacturing in the U.S. is still expanding, albeit slightly slower. Both PMI and ISM indexes ticked down, however indicated growth.

The upbeat economic data should be a positive, but ironically, has markets fretting that they may need to retool their holdings.

The S&P 500 (SPX) fell 17 points, or 0.9%, to 1,955.21, with industrials and materials leading the losses. Nine of 10 main sectors are trading lower. The Dow Jones Industrial Average (DJI) dropped 157 points, or 0.9%, to 16,885.42. The Nasdaq Composite (RIXF) shed 50 points, or 1.1%, to 4,442.43.

Wall Street stocks on Tuesday limped through the last day of trading for the month and third quarter after a mixed bag of economic data. The S&P 500 lost 1.6% last month, but eked out a 0.6% gain over the third quarter.

A rising dollar (USDJPY) could propel U.S. stocks to fresh gains, a report in The Wall Street Journal forecast. Investors will be looking for companies that could benefit from a stronger dollar, such as consumer-focused companies like airlines or retailers, Scott Migliori, chief investment officer for U.S. stocks at Allianz Global Investors, told the WSJ.

The dollar (USDJPY) tapped the 110-yen level for the first time since 2008 in Asia, after weak retail sales in Australia pushed that country's currency lower against the dollar, causing a ripple effect and the dollar/yen jump.

Eyes on ADP, manufacturing: Private-sector hiring picked up slightly in September, marking the sixth consecutive month of above-200,000 job gains, according to data released Wednesday. Economists will use this data as a guide leading up to Friday's nonfarm-payrolls report, where expectations are for a gain of 220,000 jobs.

U.S. manufacturing companies grew at slower but still rapid pace in September, a survey of executives found. The final Markit reading of U.S. manufacturing conditions in September fell slightly, but still, the index is just a hair below the highest level in more than four years. Separately, outlays for U.S. construction projects unexpectedly fell in August, the U.S. Commerce Department reported.

Autos and biotechs: Monthly sales reports from auto makers are trickling in. Expectations are for sales to slow to an annual 16.5 million last month, from 17.5 million in August. Ford Motor Co. (F) September sales dropped 3% and shares fell 1%. General Motors (GM.XX) sales rose 19.4%, but shares were flat.

Tekmira Pharmaceuticals Corp. (TKMR) surged 18% after the Center for Disease Control and Prevention confirmed the first known Ebola case diagnosed in the U.S.

Other companies working on treatments for the deadly virus also were active in early trading: BioCryst Pharmaceuticals (BCRX) rose 2.7%, Sarepta Therapeutics Inc. (SRPT) rose 3.4%. Also read: U.S. Ebola case boosts drug makers working on treatments

Other markets: Oil prices(CLX4) staged a moderate recovery, after a selloff on Tuesday that pushed prices to their lowest in more than a year. Gold prices(GCZ4) rose $5 to 1,216.8.

Supermarkets were under pressure on the FTSE 100 after sales fell at Sainsbury PLC and U.K. regulators announced a probe into Tesco PLC over its accounting practices. The Stoxx Europe 600 index was slightly lower.

The Nikkei 225 index eased, while Hong Kong and Chinese markets were closed for a holiday. Pro-democracy rallies spread further across Hong Kong on Wednesday, which had some worried about the demonstration escalating.

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